We present a novel confocal laser method (CLM) for precise testing of the dioptric power of both positive and negative intraocular lens (IOL) implants. The CLM principle is based on a simple fiber-optic confocal laser design inclu

Gold nanoparticles (NPs) have highly efficient multi-photon-induced luminescence. In this paper, we record the two-photon images of gold NPs, lymphoma cell line Karpas 299, and Karpas 299 incubated with 30-nm-diameter gold NPs and

Second-harmonic generation (SHG) microscopy is a recently developed nonlinear optical imaging modality for imaging tissue structures with submicron resolution and is a potent tool for visualizing pathological effects of diseases.

The sensitivity of diffuse optical tomography (DOT) imaging exponentially decreases with the increase of photon penetration depth, which leads to a poor depth resolution for DOT. In this letter, an exponential adjustment method (E

We present a full three-dimensional, featured-data algorithm for time-domain fluorescence diffuse optical tomography that inverts the Laplace-transformed time-domain coupled diffusion equations and employs a pair of appropriate tr

Digital radiography (DR) and whole-body fluorescent optical imaging (WFOI) have been widely applied in the field of molecular imaging, with the advantages in tissues and functional imaging. The integration of them contributes to t

The feasibility of measuring crater geometries by use of optical coherence tomography (OCT) is examined. Bovine shank bone on a motorized translation stage with a motion velocity of 3 mm/s is ablated with a pulsed CO2 laser in vit

We experimentally and theoretically investigated the performance of a fiber-optic based Fourier-domain common-path optical coherence tomography (OCT). The fiber-optic common-path OCT operated at the 840-nm center wavelength. The r

A novel spectral calibration method is developed for spectral domain optical coherence tomography system. The method is based on two measurements of interference spectra from two reference mirror positions. It removes the influenc

Spectral domain polarization-sensitive optical coherence tomography (SDPS-OCT) is a depth-resolved polarization-sensitive interferometry which integrates polarization optics into spectral domain optical coherence tomography (SD-OC

The objective of this study is to demonstrate that tensile stress resulting due to applied force on cornea can be accurately measured by using a time-domain common-path optical coherence tomography (OCT) system with an external co

The emergent light distribution of a new type of contact laser scalpel is measured in three different states using a light sensor. The relationship between the angle and the light intensity is analyzed. The results show that the s

A surface plasmon resonance (SPR) sensing system based on the optical cavity enhanced detection technique is experimentally demonstrated. A fiber-optic laser cavity is built with a SPR sensor inside. By measuring the laser output

Different types of femtosecond optical tweezers have become a powerful tool in the modern biological field. However, how to control the irregular targets, including biological cells, using femtosecond optical tweezers remains to b

A novel structure of fiber optic biosensor and its principle are introduced. The sample is detected in microchannels of several microns diameter in fiber optic biosensors. The relation between the optic fiber tapered angle and the

The ultra-compact biosensor based on the two-dimensional (2D) photonic crystal (PhC) microcavity is investigated. The performances of the sensor are analyzed theoretically using the Fabry-Perot (F-P) cavity model and simulated usi

To confirm the existence and properties of human meridians, the optical transport properties along the pericardium meridian and tissues around the pericardium meridian are studied noninvasively on twenty healthy volunteers in vivo

A spatial distribution of diffuse reflectance produced by obliquely incident light is not centered about the point of light entry. The value of shift in the center of diffuse reflectance is directly related to the absorption coeff

Reconstruction of absorption coefficient \mu_{a} and scattering coefficient \mu~~{s} is very important for applications of diffuse optical tomography and near infrared spectroscopy. Aiming at the early cancer detection of cervix

The Raman spectra from leukemic cell line (HL60) and normal human peripheral blood mononuclear cells (PBMCs) are obtained by confocal micro-Raman spectroscopy using near-infrared laser (785 nm) excitation. The scanning range is fr

A feasible method of combining the concept of fluorescence half-life and the power dependent photobleaching rate for characterizing the practical photostability of fluorescent proteins (FPs) was introduced. Furthermore, by using a

To investigate the effect of photodynamic therapy (PDT) with hematoporphrin monomethyl ether (HMME) on bovine immunodeficiency virus (BIV) can provide the basis theory for photoinactivation of human immunodeficiency virus (HIV). T

We investigated the effect of photodynamic therapy (PDT) with hematoporphyrin monomethyl ether (HMME) on the viability of Streptococcus mutans (S. mutans) cells on biofilms in vitro. Streptococcus mutans is the primary etiological

In landmark-based image registration, estimating the landmark correspondence plays an important role. In this letter, a novel landmark correspondence estimation technique using mean shift algorithm is proposed. Image corner points