The cerebral blood flow (CBF) alterations related to sound-induced opening of the blood–brain barrier (BBB) in adult mice are studied using laser speckle contrast imaging (LSCI) and wavelet analysis of vascular physiology. The res

To visualize the structure and organization of the brain is a fundamental requirement in the research of neuroscience. Here, combining with two-photon excitation fluorescence microscopy and transgenetic mouse GAD67, we demonstrate

In this Letter, we present a high-speed volumetric imaging system based on structured illumination and an electrically tunable lens (ETL), where the ETL performs fast axial scanning at hundreds of Hz. In the system, a digital micr

We report a new application of optical coherence tomography (OCT) to investigate the cranial meninges in an animal model of brain injury in vivo. The injury is induced in a mouse due to skull thinning, in which the repeated and ex

Multiple reference optical coherence tomography (MR-OCT) is a recently developed, low-cost and compact time-domain OCT solution for primary care and consumer level applications. A combination of a voice coil actuator and a partial

The biochemical composition of atherosclerotic plaques is closely related to plaque stability and, therefore, to the associated risk of plaque evolution and rupture. Combinations of current imaging modalities, such as optical cohe

A three-level lambda system driven by multicolor control, pump, and probe fields is investigated. The pump and probe fields are derived from the same laser with opposite propagating directions. Due to the Doppler effect, the zero

The Cramer–Rao lower bound on range error is modeled for pseudo-random ranging systems using Geiger-mode avalanche photodiodes. The theoretical results are shown to agree with the Monte Carlo simulation, satisfying boundary evalua

A 1550 nm Q-switched fiber laser using a carbon platinum saturable absorber deposited on side-polished fiber (SPF) is proposed and demonstrated. The SPF is approximately 2 mm with a polarization-dependent loss (PDL) of 0.4 dB and

We propose a high temperature-sensitive long period fiber grating (LPFG) sensor fabricated by using the femtosecond laser transversal-scanning method. The femtosecond pulses scan over the whole fiber core and some part of the clad

An approach for full duty frequency-doubled triangle shape lightwave generation is proposed and demonstrated. It requires a dual-parallel Mach–Zehnder modulator (DP-MZM) driven by a sinusoidal signal. A stop band filter is coupled

Reflective fiber optic sensors have advantages for surface roughness measurements of some special workpieces, but their measuring precision and efficiency need to be improved further. A least-squares support vector machine (LS-SVM

We experimentally compare the output abilities of lightly and heavily doped Ti:Sapphire (Ti:S) amplifiers with diameters as large as 150 mm. Although a lightly doped Ti:S is more favorable to overcome parasitic lasing (PL) and tra

A high pulse repetition frequency (PRF), high energy Ho:YAG laser directly pumped by a Tm-doped fiber laser and its application to a mid-infrared ZnGeP2 (ZGP) optical parametric oscillator (OPO) is demonstrated. The maximum polari

We propose a nonparallel double-grating structure in a spectral-beam combining technique, where two gratings are placed nonparallel satisfying the Littrow mount in the focal region of the convergent lens. The most attractive advan

Developing natural “free space” frequency upconversion is essential for photonic integrated circuits. In a single-crystal lithium niobate thin film planar waveguide of less than 1 μm thickness, we achieve type I and type II mode p

An injection-seeded single-resonant optical parametric oscillator (SROPO) with single frequency nanosecond pulsed 2.05 μm wavelength output is presented. Based on two potassium titanyl phosphate crystals and pumped by a 1064 nm si

A hollow-core metal-cladding waveguide (HCMW) optofluidic resonator that works based on a free-space coupling technique is designed. An HCMW can excite ultra-high-order modes (UOMs) at the coupled angle, which can be used as an op

As perovskite solar cells show tremendous potential for widespread applications, we find that adding inorganic thermal-stable cesium ions into MAPbI3 results in significantly improves thermal stability. For un-encapsulated perovsk

The authors would like to apologize for an error in the paper Chinese Optics Letters vol. 15, no. 3, page 030010. On page 030010-3, the caption for Figs. 5 (a)–(c) should read “2 μm...

Loss is inevitable for the optical system due to the absorption of materials, scattering caused by the defects, and surface roughness. In quantum optical circuits, the loss can not only reduce the intensity of the signal, but also

A scheme is proposed for tunable all-optical switching based on the double-dark states in a five-level atom-cavity system. In the scheme, the output signal light of the reflection and the transmission channels can be switched on o

Nonclassical optical frequency combs play essential roles in quantum computation in the continuous variable regime. In this work, we generate multimode nonclassical frequency comb states using a degenerate type-I synchronously pum