Fig. 1. Schematic of photo-uncaging. (a) Increase of cytosolic Ca²⁺ induced by photoactivated caged-Ca²⁺ and caged-IP₃; (b) increase of synaptic Ca²⁺ induced by photoactivated caged-glutamate

Fig. 2. Schematics of photo uncaging by single photon excitation and two-photon excitation. (a) Optical path of uncaging system;

Fig. 3. Optogenetic activation of Ca²⁺ signaling. (a) Experimental steps for optogenetics; (b) schematics of light activation of OptoSTIM1 and Opto-α₁AR

Fig. 4. Mechanism of laser-cell interaction. (a) Single photon damage to cells; (b) mechanism for laser induced intracellular Ca²⁺ increase

Fig. 5. Schematic of femtosecond laser induced Ca²⁺ release

Fig. 6. Schematic of specific SOC modulation by femtosecond laser