Chinese Journal of Lasers, Volume. 47, Issue 2, 207012(2020)

Recent Advances in Nanophotosensitizers for Antibacterial Photodynamic Therapy

Zhang Chang1, Ren En1, Pang Xin2, Li Lei1, and Liu Gang1
Author Affiliations
  • 1Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University,Xiamen, Fujian 361102, China
  • 2Department of Magnetic Resonance, the First Affiliated Hospital of Zhengzhou University,Zhengzhou, Henan 450052, China
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    Figures & Tables(4)
    Schematic illustration of APDT for nanoparticles
    Schematic illustration of nanostructured phthalocyanine self-assembly[10]
    Schematic illustration of nanoliposome system for antibacterial treatment[46]
    • Table 1. Common inorganic nanophotosensitizers

      View table

      Table 1. Common inorganic nanophotosensitizers

      PhotosensitizerAPDT parameterActivity of microbeReference
      Nitrogen-doped graphenequantum dots0.1 W/cm2, 670 nmE. coli was eliminated nearly 100% after 3 min laser irradiation exposure.[19]
      Fullerene monoadductsWhite light: 150 mW/cm2; UV light: 30 mW/cm2When excited by UVA light or white light,fullerene monoadducts can kill three different classes of pathogenic microbial cells, such as MRSA, E.coli, and fungal yeast C. albicans.[20]
      Black phosphorusnanosheetsXenon lamp: 200 W, 1 m highBlack phosphorus nanosheets can kill 98.90% and 99.51% E.coli within 10 min.[21]
      Chitosan-assisted MoS2nanosheets as coatingin titanium implants660 nm, 0.5 W/cm2When irradiated by only 660 nm visible light for 10 min, the nanosheets exhibit antibacterial efficacy of 91.58% and 92.52% against E.coli and S.aureus, respectively.[22]
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    Zhang Chang, Ren En, Pang Xin, Li Lei, Liu Gang. Recent Advances in Nanophotosensitizers for Antibacterial Photodynamic Therapy[J]. Chinese Journal of Lasers, 2020, 47(2): 207012

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    Paper Information

    Category: biomedical photonics and laser medicine

    Received: Sep. 18, 2019

    Accepted: --

    Published Online: Feb. 21, 2020

    The Author Email:

    DOI:10.3788/CJL202047.0207012

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