Laser & Optoelectronics Progress, Volume. 61, Issue 10, 1000003(2024)
Research Progress and Application of Confocal Scanning Laser Ophthalmoscope (Invited)
Fig. 1. Schematic diagram of field of view range for fundus imaging. (a) Lateral image of human eye from e-anatomy; (b) indocyanine green angiography image collected with Optos, in which four vortex veins can be seen
Fig. 9. Human eye photoreceptor image obtained from AOSLO. (a) At 1° eccentricity of temporal side of fovea, bright spot in image is cone cells[51]; (b) at 10° eccentricity of fovea shows intact cones (large cells) with rod cells embedded in space[56]; (c) at inner segment of cone cells is shown at 10° eccentricity of temporal side of fovea, image shows inner segment of cone cells, inner segment of rod cells in gap cannot be distinguished due to its small size[51]
Fig. 10. Retinal vascular imaging. (a) AOSLO FA map of central foveal avascular area[96]; (b) contrast vascular perfusion map of central foveal avascular area movement[98]; (c) capillary diagram around retinal nerve papillary fossa obtained by offset pinhole AOSLO[74]; (d) capillary map at 5° eccentricity on nasal side of fovea obtained by dark field AOSLO[98]; (e) capillary map of same region in (d) obtained by split-detector AOSLO[98]
Fig. 11. AOSLO imaging results of various retinal tissue structures. (a) RPE image of healthy human eyes[52]; (b) tilted bundle structure is temporal NFL[106]; (c) vertical fine bundle structure is Henry fibers, while larger transverse inclined bundle structure with larger background is NFL[108]; (d) G-CaMP3 labeled fluorescence images of mouse GCs[111]; (e) G-CaMP5 labeled fluorescence images of GCs in macaques[112]; (f) HRA SLO video disc image developed by Heidelberg is overlaid with LC image obtained by AOSLO, and clear LC structure can be seen at arrow[113]
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Xiadi Ye, Jiangjie Huang, Wen Kong, Lina Xing, Yi He, Guohua Shi. Research Progress and Application of Confocal Scanning Laser Ophthalmoscope (Invited)[J]. Laser & Optoelectronics Progress, 2024, 61(10): 1000003
Category: Reviews
Received: Jan. 3, 2024
Accepted: Jan. 24, 2024
Published Online: May. 9, 2024
The Author Email: He Yi (heyi@sibet.ac.cn)
CSTR:32186.14.LOP240437