Acta Optica Sinica, Volume. 43, Issue 2, 0217001(2023)

Blood Clot Ablation Effects Based on Burst-Mode Femtosecond Laser

Xiaozheng Liu1, Younan Li2, Haitao Zhang3、*, Ying Gu1,4、**, Weiwei Wu2, and Tong Zhang2
Author Affiliations
  • 1School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China
  • 2Department of Vascular Surgery, Affiliated Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China
  • 3Key Laboratory of Photonic Control Technology, Ministry of Education, Center for Photonics and Electronics, Department of Precision Instrument, Tsinghua University, Beijing 100084, China
  • 4Department of Laser Medicine, First Medical Center of PLA General Hospital, Beijing 100853, China
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    Figures & Tables(8)
    Overall experimental device diagram
    Schematic diagrams of repetition rates of laser pulses used in experiments. (a) Experimental groups 1-3; (b) experimental groups 4-6; (c) experimental groups 7-9; (d) experimental groups 10-12
    Microscopic images of ablation pits obtained by burst-mode femtosecond laser. (a) Experimental group 1; (b) experimental group 2; (c) experimental group 3; (d) experimental group 4; (e) experimental group 5; (f) experimental group 6
    Morphology data of ablation pits obtained by burst-mode femtosecond laser. (a) Experimental group 1; (b) experimental group 2;(c) experimental group 3; (d) experimental group 4; (e) experimental group 5; (f) experimental group 6
    Microscopic images of ablation pits obtained by traditional mode femtosecond laser. (a) Experimental group 7; (b) experimental group 8; (c) experimental group 9; (d) experimental group 10; (e) experimental group 11; (f) experimental group 12
    Morphology data of ablation pits obtained by traditional mode femtosecond laser. (a) Experimental group 7; (b) experimental group 8; (c) experimental group 9; (d) experimental group 10; (e) experimental group 11; (f) experimental group 12
    Fitting results of ablation experimental data
    • Table 1. Ablation experimental groups

      View table

      Table 1. Ablation experimental groups

      Experimental group No.Pulse/burst energy /μJRepetition rate /kHzScan speed /(mm·s-1Equivalent energy density /(J·cm-2
      15×4011180.0
      21018.0
      31001.8
      421360.0
      51036.0
      61003.6
      74051180.0
      81018.0
      91001.8
      10101360.0
      111036.0
      121003.6
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    Xiaozheng Liu, Younan Li, Haitao Zhang, Ying Gu, Weiwei Wu, Tong Zhang. Blood Clot Ablation Effects Based on Burst-Mode Femtosecond Laser[J]. Acta Optica Sinica, 2023, 43(2): 0217001

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    Paper Information

    Category: Medical optics and biotechnology

    Received: Jun. 27, 2022

    Accepted: Jul. 14, 2022

    Published Online: Feb. 7, 2023

    The Author Email: Zhang Haitao (guyinglaser301@163.com), Gu Ying (zhanghaitao@mail.tsinghua.edu.cn)

    DOI:10.3788/AOS221371

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