Laser & Optoelectronics Progress, Volume. 56, Issue 7, 070005(2019)
Research Progress on Label-Free Microscopic Imaging Technology
[5] Huang D, Swanson E A, Lin C P et al. Optical coherence tomography[J]. Science, 254, 1178-1181(1991).
[15] Leitgeb R A, Werkmeister R M, Blatter C et al. Doppler optical coherence tomography[J]. Progress in Retinal and Eye Research, 41, 26-43(2014).
[24] Park K, Kim J Y, Lee C et al. Handheld photoacoustic microscopy probe[J]. Scientific Reports, 7, 13359(2017).
[30] Gauderon R, Lukins P B. Sheppard C J R. Simultaneous multichannel nonlinear imaging: combined two-photon excited fluorescence and second-harmonic generation microscopy[J]. Micron, 32, 685-689(2001).
[34] Eckhardt G, Hellwarth R W. McClung F J, et al. Stimulated Raman scattering from organic liquids[J]. Physical Review Letters, 9, 455-458(1962).
[40] Yang V X D, Gordon M L, Seng-Yue E et al. . High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): imaging in vivo cardiac dynamics of xenopus laevis[J]. Optics Express, 11, 1650-1658(2003).
[41] Sudheendran N, Syed S H, Dickinson M E et al. Speckle variance OCT imaging of the vasculature in live mammalian embryos[J]. Laser Physics Letters, 8, 247-252(2011).
[42] Peterson L M, Jenkins M W, Gu S et al. 4D shear stress maps of the developing heart using Doppler optical coherence tomography[J]. Biomedical Optics Express, 3, 3022-3032(2012).
[43] Wang S, Lopez A L, Larina I V. Functional optical coherence tomography for live dynamic analysis of mouse embryonic cardiogenesis[J]. Proceedings of SPIE, 10493, 104930C(2018).
[44] Kruger R A, Lam R B, Reinecke D R et al. Photoacoustic angiography of the breast[J]. Medical Physics, 37, 6096-6100(2010).
[45] Ku G, Fornage B D, Jin X et al. Thermoacoustic and photoacoustic tomography of thick biological tissues toward breast imaging[J]. Technology in Cancer Research & Treatment, 4, 559-566(2005).
[46] Matsumoto Y, Asao Y, Yoshikawa A et al. Label-free photoacoustic imaging of human palmar vessels: a structural morphological analysis[J]. Scientific Reports, 8, 786(2018).
[47] Ferrari M. Cancer nanotechnology: opportunities and challenges[J]. Nature Reviews Cancer, 5, 161-171(2005).
[48] Yao J J. Wang L H V. Photoacoustic brain imaging: from microscopic to macroscopic scales[J]. Neurophotonics, 1, 011003(2014).
[49] Lui H, Zhao J. McLean D, et al. Real-time Raman spectroscopy for in vivo skin cancer diagnosis[J]. Cancer Research, 72, 2491-2500(2012).
[50] He J P, Wang N, Tsurui H et al. Noninvasive, label-free, three-dimensional imaging of melanoma with confocal photothermal microscopy: differentiate malignant melanoma from benign tumor tissue[J]. Scientific Reports, 6, 30209(2016).
[51] Stummer W. 5-aminolevulinic acid-derived tumor fluorescence: the diagnostic accuracy of visible fluorescence qualities as corroborated by spectrometry and histology and postoperative imaging[J]. Neurosurgery, 76, 230-231(2015).
[52] Kut C, Chaichana K L, Xi J F et al. 7(292): 292ra100[J].
[53] Ji M B, Orringer D A, Freudiger C W et al. 5(201): 201ra119[J]. label-free detection of brain tumors with stimulated Raman scattering microscopy. Science Translational Medicine(2013).
[54] Jermyn M, Mok K, Mercier Jet al. Intraoperative brain cancer detection with Raman spectroscopy in humans[J]. 7(274): 274ra19(2015).
[55] Kuzmin N V. Wesseling P, de Witt Hamer P C, et al. Third harmonic generation imaging for fast, label-free pathology of human brain tumors[J]. Biomedical Optics Express, 7, 1889-1904(2016).
[56] Losick R, Desplan C. Stochasticity and cell fate[J]. Science, 320, 65-68(2008).
[57] Muzzey D, van Oudenaarden A. Quantitative time-lapse fluorescence microscopy in single cells[J]. Annual Review of Cell and Developmental Biology, 25, 301-327(2009).
[58] Wang L D, Maslov K. Wang L H V. Single-cell label-free photoacoustic flowoxigraphy in vivo[J]. Proceedings of the National Academy of Sciences of the United States of America, 110, 5759-5764(2013).
[59] He G, Xu D, Qin H et al. In vivo cell characteristic extraction and identification by photoacoustic flow cytography[J]. Biomedical Optics Express, 6, 3748-3756(2015).
[60] Zhao Y, Yang S H, Chen C G et al. Simultaneous optical absorption and viscoelasticity imaging based on photoacoustic lock-in measurement[J]. Optics Letters, 39, 2565-2568(2014).
[61] Marrison J, Räty L, Marriott P et al. Ptychography-a label free, high-contrast imaging technique for live cells using quantitative phase information[J]. Scientific Reports, 3, 2369(2013).
[62] Lim H, Sharoukhov D, Kassim I et al. Label-free imaging of Schwann cell myelination by third harmonic generation microscopy[J]. Proceedings of the National Academy of Sciences of the United States of America, 111, 18025-18030(2014).
[63] Jüngst C, Klein M, Zumbusch A. Long-term live cell microscopy studies of lipid droplet fusion dynamics in adipocytes[J]. Journal of Lipid Research, 54, 3419-3429(2013).
[64] Kim G, Lee S, Shin S et al. Three-dimensional label-free imaging and analysis of pinus pollen grains using optical diffraction tomography[J]. Scientific Reports, 8, 1782(2018).
[65] Liu X W, Kuang C F, Hao X et al. Fluorescent nanowire ring illumination for wide-field far-field subdiffraction imaging[J]. Physical Review Letters, 118, 076101(2017).
[66] Chen Z J, Yang S H, Xing D. Optically integrated trimodality imaging system: combined all-optical photoacoustic microscopy, optical coherence tomography, and fluorescence imaging[J]. Optics Letters, 41, 1636-1639(2016).
[67] Meng X Q, Yang Y T, Zhou L H et al. Dual-responsive molecular probe for tumor targeted imaging and photodynamic therapy[J]. Theranostics, 7, 1781-1794(2017).
Get Citation
Copy Citation Text
Jia Zhang, Liang Hong, Sheng Ren, Feifan Zhou, Rui Hu, Junle Qu, Liwei Liu. Research Progress on Label-Free Microscopic Imaging Technology[J]. Laser & Optoelectronics Progress, 2019, 56(7): 070005
Category: Reviews
Received: Aug. 6, 2018
Accepted: Nov. 20, 2018
Published Online: Jul. 30, 2019
The Author Email: Liwei Liu (liulw@szu.edu.cn)