Journal of Inorganic Materials, Volume. 40, Issue 7, 754(2025)
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4. Biodistributions of CaP NDs and CaP NPs in different tissues after injection for different durations
6. Establishment and optimization of PBPK model for tumor bearing sites
Table 1. Elemental content and molar ratio of Eu:CaP NDs and Eu:CaP NPs
View tableView in ArticleTable 1. Elemental content and molar ratio of Eu:CaP NDs and Eu:CaP NPs
Sample Value Ca/(mg·L-1) P/(mg·L-1) Eu/(mg·L-1) (Eu/(Ca+Eu))/% (Ca+Eu)/P Eu:CaP NDs Actual 8.72 4.53 2.82 7.86 1.61 Theoretical — — — 8.00 1.67 Eu:CaP NPs Actual 22.50 11.85 7.23 7.82 1.59 Theoretical — — — 8.00 1.67
Table 2. Pharmacokinetic parameters of CaP NDs and CaP NPs in organ and tumor site of tumor-bearing mice
View tableView in ArticleTable 2. Pharmacokinetic parameters of CaP NDs and CaP NPs in organ and tumor site of tumor-bearing mice
Sample Parameter Liver Spleen Lung Kidney Tumor CaP NDs AUC(0-t)/(mg·h·L-1) 157.78 71.35 19.34 70.61 20.31 CLz/(L·h-1·kg-1) 0.033 0.091 0.235 0.144 0.146 CaP NPs AUC(0-t)/(mg·h·L-1) 1347.46 578.05 66.74 19.85 6.07 CLz/(L·h-1·kg-1) 0.005 0.022 0.098 0.341 1.796
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Xinli TANG, Ziyou DING, Junrui CHEN, Gang ZHAO, Yingchao HAN.
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Received: Dec. 3, 2024
Accepted: --
Published Online: Sep. 3, 2025
The Author Email: Yingchao HAN (hanyingchao@whut.edu.cn)
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