Chinese Optics Letters, Volume. 19, Issue 11, 111701(2021)
Review of photoacoustic imaging for microrobots tracking in vivo [Invited] On the Cover
[1] J. Li, B. E.-F. de Ávila, W. Gao, L. Zhang, J. Wang. Micro/nanorobots for biomedicine: delivery, surgery, sensing, and detoxification. Sci. Robot., 2, eaam6431(2017).
[2] B. E.-F. de Ávila, P. Angsantikul, J. Li, M. Angel Lopez-Ramirez, D. E. Ramírez-Herrera, S. Thamphiwatana, C. Chen, J. Delezuk, R. Samakapiruk, V. Ramez, L. Zhang, J. Wang. Micromotor-enabled active drug delivery for in vivo treatment of stomach infection. Nat. Commun., 8, 272(2017).
[3] J. Li, X. Li, T. Luo, R. Wang, C. Liu, S. Chen, D. Li, J. Yue, S. H. Cheng, D. Sun. Development of a magnetic microrobot for carrying and delivering targeted cells. Sci. Robot., 3, eaat8829(2018).
[4] X. Z. Chen, B. Jang, D. Ahmed, C. Hu, C. De Marco, M. Hoop, F. Mushtaq, B. J. Nelson, S. Pané. Small-scale machines driven by external power sources. Adv. Mater., 30, 1705061(2018).
[5] Y. Wu, T. Si, J. Shao, Z. Wu, Q. He. Near-infrared light-driven Janus capsule motors: fabrication, propulsion, and simulation. Nano Res., 9, 3747(2016).
[6] H. Zeng, P. Wasylczyk, C. Parmeggiani, D. Martella, M. Burresi, D. S. Wiersma. Light-fueled microscopic walkers. Adv. Mater., 27, 3883(2015).
[7] S. Tottori, L. Zhang, F. Qiu, K. K. Krawczyk, A. Franco-Obregón, B. J. Nelson. Magnetic helical micromachines: fabrication, controlled swimming, and cargo transport. Adv. Mater., 24, 811(2012).
[8] C. Peters, M. Hoop, S. Pané, B. J. Nelson, C. Hierold. Degradable magnetic composites for minimally invasive interventions: device fabrication, targeted drug delivery, and cytotoxicity tests. Adv. Mater., 28, 533(2016).
[9] W. Gao, R. Dong, S. Thamphiwatana, J. Li, W. Gao, L. Zhang, J. Wang. Artificial micromotors in the mouse’s stomach: a step toward in vivo use of synthetic motors. ACS Nano., 9, 117(2015).
[10] D. Li, Y. Liu, Y. Yang, Y. Shen. A fast and powerful swimming microrobot with a serrated tail enhanced propulsion interface. Nanoscale, 10, 19673(2018).
[11] V. Magdanz, S. Sanchez, O. G. Schmidt. Development of a sperm-flagella driven micro-bio-robot. Adv. Mater., 25, 6581(2013).
[12] B. Esteban-Fernández de Ávila, P. Angsantikul, J. Li, W. Gao, L. Zhang, J. Wang. Micromotors go in vivo: from test tubes to live animals. Adv. Funct. Mater., 28, 1705640(2018).
[13] X. Yan, Q. Zhou, M. Vincent, Y. Deng, J. Yu, J. Xu, T. Xu, T. Tang, L. Bian, Y. X. J. Wang, K. Kostarelos, L. Zhang. Multifunctional biohybrid magnetite microrobots for imaging-guided therapy. Sci. Robot., 2, eaaq1155(2017).
[14] B. Wang, K. F. Chan, K. Yuan, Q. Wang, X. Xia, L. Yang, H. Ko, Y. J. Wang, J. Jao, Y. Sung, P. Wai, Y. Chiu, L. Zhang. Endoscopy-assisted magnetic navigation of biohybrid soft microrobots with rapid endoluminal delivery and imaging. Sci. Robot., 6, eabd2813(2021).
[15] Q. Wang, K. F. Chan, K. Schweizer, X. Du, D. Jin, S. C. H. Yu, B. J. Nelson, L. Zhang. Ultrasound Doppler-guided real-time navigation of a magnetic microswarm for active endovascular delivery. Sci. Adv., 7, eabe5914(2021).
[16] Q. Wang, L. Zhang. External power-driven microrobotic swarm: from fundamental understanding to imaging-guided delivery. ACS Nano., 15, 149(2021).
[17] Q. Wang, L. Zhang. Ultrasound imaging and tracking of micro/nanorobots: from individual to collectives. IEEE Open J. Nanotechnol., 1, 6(2020).
[18] Q. Wang, L. Yang, J. Yu, P. W. Y. Chiu, Y. P. Zheng, L. Zhang. Real-time magnetic navigation of a rotating colloidal microswarm under ultrasound guidance. IEEE Trans. Biomed. Eng., 67, 3403(2020).
[19] S. Jeong, H. Choi, C. Lee, G. Go, D. S. Sim, K. S. Lim, M. H. Jeong, S. Y. Ko, J. Park, S. Park. Therapeutic intravascular microrobot through compensation of resistance and mutual inductance in electromagnetic actuation system. Int. J. Control. Autom. Syst., 13, 1465(2015).
[20] S. Pané, J. Puigmartí-Luis, C. Bergeles, X.-Z. Chen, E. Pellicer, J. Sort, V. Počepcová, A. Ferreira, B. J. Nelson. Imaging technologies for biomedical micro- and nanoswimmers. Adv. Mater. Technol., 4, 1800575(2019).
[21] M. Medina-Sánchez, O. G. Schmidt. Medical microbots need better imaging and control. Nature, 545, 406(2017).
[22] D. Li, C. Liu, Y. Yang, L. Wang, Y. Shen. Micro-rocket robot with all-optic actuating and tracking in blood. Light Sci. Appl., 9, 84(2020).
[23] T. Wei, J. Liu, D. Li, S. Chen, Y. Zhang, J. Li, L. Fan, Z. Guan, C. Lo, L. Wang, K. Man, D. Sun. Development of magnet-driven and image-guided degradable microrobots for the precise delivery of engineered stem cells for cancer therapy. Small, 16, 1906908(2020).
[24] L. V. Wang, J. Yao. A practical guide to photoacoustic tomography in the life sciences. Nat. Methods, 13, 627(2016).
[25] S. Manohar, D. Razansky. Photoacoustics: a historical review. Adv. Opt. Photon., 8, 586(2016).
[26] M. Xu, L. V. Wang. Photoacoustic imaging in biomedicine. Rev. Sci. Instrum., 77, 041101(2006).
[27] T. Feng, Y. Zhu, Y. Xie, D. Ta, J. Yuan, Q. Cheng. Feasibility study for bone health assessment based on photoacoustic imaging method. Chin. Opt. Lett., 18, 121704(2020).
[28] A. Danielli, K. I. Maslov, A. Garcia-Uribe, A. M. Winkler, C. Li, L. Wang, Y. Chen, G. W. Dorn, L. V. Wang. Label-free photoacoustic nanoscopy. J. Biomed. Opt., 19, 086006(2014).
[29] C. Liu, Y. Liang, L. Wang. Optical-resolution photoacoustic microscopy of oxygen saturation with nonlinear compensation. Biomed. Opt. Express, 10, 3061(2019).
[30] L. Lin, P. Hu, J. Shi, C. M. Appleton, K. Maslov, L. Li, R. Zhang, L. V. Wang. Single-breath-hold photoacoustic computed tomography of the breast. Nat. Commun., 9, 2352(2018).
[31] Y. Matsumoto, Y. Asao, A. Yoshikawa, H. Sekiguchi, M. Takada, M. Furu, S. Saito, M. Kataoka, H. Abe, T. Yagi, K. Togashi, M. Toi. Label-free photoacoustic imaging of human palmar vessels: a structural morphological analysis. Sci. Rep., 8, 786(2018).
[32] A. P. Jathoul, J. Laufer, O. Ogunlade, B. Treeby, B. Cox, E. Zhang, P. Johnson, A. R. Pizzey, B. Philip, T. Marafioti, M. F. Lythgoe, R. B. Pedley, M. A. Pule, P. Beard. Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter. Nat. Photon., 9, 239(2015).
[33] J. Chen, Y. Zhang, X. Li, J. Zhu, D. Li, S. Li, C.-S. Lee, L. Wang. Confocal visible/NIR photoacoustic microscopy of tumors with structural, functional, and nanoprobe contrasts. Photon. Res., 8, 1875(2020).
[34] C. Liu, Y. Liang, L. Wang. Single-shot photoacoustic microscopy of hemoglobin concentration, oxygen saturation, and blood flow in sub-microseconds. Photoacoustics, 17, 100156(2020).
[35] C. Liu, J. Chen, Y. Zhang, J. Zhu, L. Wang. Five-wavelength optical-resolution photoacoustic microscopy of blood and lymphatic vessels. Adv. Photon., 3, 016002(2021).
[36] L. Lin, J. Yao, L. Li, L. V. Wang. In vivo photoacoustic tomography of myoglobin oxygen saturation. J. Biomed. Opt., 21, 061002(2015).
[37] B. Wang, J. L. Su, J. Amirian, S. H. Litovsky, R. Smalling, S. Emelianov. Detection of lipid in atherosclerotic vessels using ultrasound-guided spectroscopic intravascular photoacoustic imaging. Opt. Express, 18, 4889(2010).
[38] C. Yin, G. Wen, C. Liu, B. Yang, S. Lin, J. Huang, P. Zhao, S. H. D. Wong, K. Zhang, X. Chen, G. Li, X. Jiang, J. Huang, K. Pu, L. Wang, L. Bian. Organic semiconducting polymer nanoparticles for photoacoustic labeling and tracking of stem cells in the second near-infrared window. ACS Nano., 12, 12201(2018).
[39] Y. Dai, X. Yu, J. Wei, F. Zeng, Y. Li, X. Yang, Q. Luo, Z. Zhang. Metastatic status of sentinel lymph nodes in breast cancer determined with photoacoustic microscopy via dual-targeting nanoparticles. Light Sci. Appl., 9, 164(2020).
[40] H. Fang, K. Maslov, L. V. Wang. Photoacoustic Doppler effect from flowing small light-absorbing particles. Phys. Rev. Lett., 99, 184501(2007).
[41] J. Yao, K. I. Maslov, Y. Shi, L. A. Taber, L. V. Wang. In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth. Opt. Lett., 35, 1419(2010).
[42] L. Xie, X. Pang, X. Yan, Q. Dai, H. Lin, J. Ye, Y. Cheng, Q. Zhao, X. Ma, X. Zhang, G. Liu, X. Chen. Photoacoustic imaging-trackable magnetic microswimmers for pathogenic bacterial infection treatment. ACS Nano., 14, 2880(2020).
[43] L. Li, L. Zhu, C. Ma, L. Lin, J. Yao, L. Wang, K. Maslov, R. Zhang, W. Chen, J. Shi, L. V. Wang. Single-impulse panoramic photoacoustic computed tomography of small-animal whole-body dynamics at high spatiotemporal resolution. Nat. Biomed. Eng., 1, 0071(2017).
[44] P. Zhang, L. Li, L. Lin, J. Shi, L. V. Wang. In vivo superresolution photoacoustic computed tomography by localization of single dyed droplets. Light Sci. Appl., 8, 36(2019).
[45] W. Choi, C. Kim. Toward in vivo translation of super-resolution localization photoacoustic computed tomography using liquid-state dyed droplets. Light Sci. Appl., 8, 57(2019).
[46] J. Yao, L. Wang, J. M. Yang, K. I. Maslov, T. T. W. Wong, L. Li, C. H. Huang, J. Zou, L. V. Wang. High-speed label-free functional photoacoustic microscopy of mouse brain in action. Nat. Methods, 12, 407(2015).
[47] Y. Li, T. T. W. Wong, J. Shi, H. C. Hsu, L. V. Wang. Multifocal photoacoustic microscopy using a single-element ultrasonic transducer through an ergodic relay. Light Sci. Appl., 9, 135(2020).
[48] M. Chen, H. J. Knox, Y. Tang, W. Liu, L. Nie, J. Chan, J. Yao. Simultaneous photoacoustic imaging of intravascular and tissue oxygenation. Opt. Lett., 44, 3773(2019).
[49] Y. Liang, L. Jin, B.-O. Guan, L. Wang. 2 MHz multi-wavelength pulsed laser for functional photoacoustic microscopy. Opt. Lett., 42, 1452(2017).
[50] J. Kim, J. Y. Kim, S. Jeon, J. W. Baik, S. H. Cho, C. Kim. Super-resolution localization photoacoustic microscopy using intrinsic red blood cells as contrast absorbers. Light Sci. Appl., 8, 103(2019).
[51] E. Vienneau, W. Liu, J. Yao. Dual-view acoustic-resolution photoacoustic microscopy with enhanced resolution isotropy. Opt. Lett., 43, 4413(2018).
[52] P. K. Upputuri, M. Pramanik. Recent advances toward preclinical and clinical translation of photoacoustic tomography: a review. J. Biomed. Opt., 22, 041006(2016).
[53] L. V. Wang, S. Hu. Photoacoustic tomography: in vivo imaging from organelles to organs. Science, 335, 1458(2012).
[54] J. Yao, A. A. Kaberniuk, L. Li, D. M. Shcherbakova, R. Zhang, L. Wang, G. Li, V. V. Verkhusha, L. V. Wang. Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe. Nat. Methods, 13, 67(2015).
[55] X. Wang, S. Yang. Imaging of human wrist joint by a flexible-transducer-based morphological-adaptive photoacoustic tomography: a feasibility study. Chin. Opt. Lett., 17, 091701(2019).
[56] G. Li, L. Li, L. Zhu, J. Xia, L. V. Wang. Multiview Hilbert transformation for full-view photoacoustic computed tomography using a linear array. J. Biomed. Opt., 20, 066010(2015).
[57] L. Wang, G. Li, J. Xia, L. V. Wang. Ultrasonic-heating-encoded photoacoustic tomography with virtually augmented detection view. Optica, 2, 307(2015).
[58] L. Lin, P. Hu, X. Tong, S. Na, R. Cao, X. Yuan, D. C. Garrett, J. Shi, K. Maslov, L. V. Wang. High-speed three-dimensional photoacoustic computed tomography for preclinical research and clinical translation. Nat. Commun., 12, 882(2021).
[59] K. Huda, C. Wu, J. G. Sider, C. L. Bayer. Spherical-view photoacoustic tomography for monitoring in vivo placental function. Photoacoustics, 20, 100209(2020).
[60] Y. Zhang, L. Wang. Video-rate ring-array ultrasound and photoacoustic tomography. IEEE Trans. Med. Imaging., 39, 4369(2020).
[61] H. Estrada, A. Ozbek, J. Robin, S. Shoham, D. Razansky. Spherical array system for high-precision transcranial ultrasound stimulation and optoacoustic imaging in rodents. IEEE Trans. Ultrason. Ferroelectr. Freq. Control., 68, 107(2021).
[62] M. Heijblom, W. Steenbergen, S. Manohar. Clinical photoacoustic breast imaging: the Twente experience. IEEE Pulse, 6, 42(2015).
[63] F. Zheng, X. Zhang, C. T. Chiu, B. L. Zhou, K. K. Shung, H. F. Zhang, S. Jiao. Laser-scanning photoacoustic microscopy with ultrasonic phased array transducer. Biomed. Opt. Express, 3, 2694(2012).
[64] S. Li, Q. Deng, Y. Zhang, X. Li, G. Wen, X. Cui, Y. Wan, Y. Huang, J. Chen, Z. Liu, L. Wang, C. S. Lee. Rational design of conjugated small molecules for superior photothermal theranostics in the NIR-II biowindow. Adv. Mater., 32, 2001146(2020).
[65] G. Wen, X. Li, Y. Zhang, X. Han, X. Xu, C. Liu, K. W. Y. Chan, C. S. Lee, C. Yin, L. Bian, L. Wang. Effective phototheranostics of brain tumor assisted by near-infrared-II light-responsive semiconducting polymer nanoparticles. ACS Appl. Mater. Interfaces., 12, 33492(2020).
[66] M. Zha, X. Lin, J. S. Ni, Y. Li, Y. Zhang, X. Zhang, L. Wang, K. Li. An ester-substituted semiconducting polymer with efficient nonradiative decay enhances NIR-II photoacoustic performance for monitoring of tumor growth. Angew. Chemie–Int. Ed., 59, 23268(2020).
[67] J. Zhang, G. Wen, W. Wang, K. Cheng, Q. Guo, S. Tian, C. Liu, H. Hu, Y. Zhang, H. Zhang, L. Wang, H. Sun. Controllable cleavage of C–N bond-based fluorescent and photoacoustic dual-modal probes for the detection of H2S in living mice. ACS Appl. Bio Mater., 4, 2020(2021).
[68] J. Xia, C. Kim, J. F. Lovell. Opportunities for photoacoustic-guided drug delivery. Curr. Drug Targets., 16, 571(2015).
[69] N. Gandhi, M. Allard, S. Kim, P. Kazanzides, M. A. L. Bell. Photoacoustic-based approach to surgical guidance performed with and without a da Vinci robot. J. Biomed. Opt., 22, 121606(2017).
[70] Z. Wu, L. Li, Y. Yang, P. Hu, Y. Li, S. Y. Yang, L. V. Wang, W. Gao. A microrobotic system guided by photoacoustic computed tomography for targeted navigation in intestines in vivo. Sci. Robot, 4, eaax0613(2019).
[71] L. Labanieh, R. G. Majzner, C. L. Mackall. Programming CAR-T cells to kill cancer. Nat. Biomed. Eng., 2, 377(2018).
[72] A. Aziz, M. Medina-Sánchez, J. Claussen, O. G. Schmidt. Real-time optoacoustic tracking of single moving micro-objects in deep phantom and ex vivo tissues. Nano Lett., 19, 6612(2019).
[73] Y. Yan, W. Jing, M. Mehrmohammadi. Photoacoustic imaging to track magnetic-manipulated micro-robots in deep tissue. Sensors, 20, 2816(2020).
[74] G. S. Jeng, M. L. Li, M. W. Kim, S. J. Yoon, J. J. Pitre, D. S. Li, I. Pelivanov, M. O’Donnell. Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction. Nat. Commun., 12, 716(2021).
[75] H. Su. Optical-resolution photoacoutic microscopy(2010).
[76] K. Maslov, H. F. Zhang, S. Hu, L. V. Wang. Optical-resolution photoacoustic microscopy for in vivo imaging of single capillaries. Opt. Lett., 33, 929(2008).
[77] S. Hu, K. Maslov, L. V. Wang. Second-generation optical-resolution photoacoustic microscopy with improved sensitivity and speed. Opt. Lett., 36, 1134(2011).
[78] Y. Liang, J.-W. Liu, L. Jin, B.-O. Guan, L. Wang. Fast-scanning photoacoustic microscopy with a side-looking fiber optic ultrasound sensor. Biomed. Opt. Express, 9, 5809(2018).
[79] B. Rao, K. Maslov, A. Danielli, R. Chen, K. K. Shung, Q. Zhou, L. V. Wang. Real-time four-dimensional optical-resolution photoacoustic microscopy with Au nanoparticle-assisted subdiffraction-limit resolution. Opt. Lett., 36, 1137(2011).
[80] W. Qin, T. Jin, H. Guo, L. Xi. Large-field-of-view optical resolution photoacoustic microscopy. Opt. Express, 26, 4271(2018).
[81] C. Zhang, H. Zhao, S. Xu, N. Chen, K. Li, X. Jiang, L. Liu, Z. Liu, L. Wang, K. K. Y. Wong, J. Zou, C. Liu, L. Song. Multiscale high-speed photoacoustic microscopy based on free-space light transmission and a MEMS scanning mirror. Opt. Lett., 45, 4312(2020).
[82] J. Lee, S. Han, D. Seong, J. Lee, S. Park, R. Eranga Wijesinghe, M. Jeon, J. Kim. Fully waterproof two-axis galvanometer scanner for enhanced wide-field optical-resolution photoacoustic microscopy. Opt. Lett., 45, 865(2020).
[83] L. Wang, K. Maslov, L. V. Wang. Single-cell label-free photoacoustic flowoxigraphy in vivo. Proc. Natl. Acad. Sci. U. S. A., 110, 5759(2013).
[84] L. Wang, K. Maslov, J. Yao, B. Rao, L. V. Wang. Fast voice-coil scanning optical-resolution photoacoustic microscopy. Opt. Lett., 36, 139(2011).
[85] J. Chen, Y. Zhang, L. He, Y. Liang, L. Wang. Wide-field polygon-scanning photoacoustic microscopy of oxygen saturation at 1-MHz A-line rate. Photoacoustics., 20, 100195(2020).
[86] J. Y. Kim, C. Lee, K. Park, S. Han, C. Kim. High-speed and high-SNR photoacoustic microscopy based on a galvanometer mirror in non-conducting liquid. Nat. Publ. Gr., 6, 34803(2016).
[87] J. Y. Kim, C. Lee, K. Park, G. Lim, C. Kim. Fast optical-resolution photoacoustic microscopy using a 2-axis water-proofing MEMS scanner. Sci. Rep., 5, 7932(2015).
[88] B. Lan, W. Liu, Y. Wang, J. Shi, Y. Li, S. Xu, H. Sheng, Q. Zhou, J. Zou, U. Hoffmann, W. Yang, J. Yao. High-speed widefield photoacoustic microscopy of small-animal hemodynamics. Biomed. Opt. Express, 9, 4689(2018).
Get Citation
Copy Citation Text
Dengfeng Li, Yachao Zhang, Chao Liu, Jiangbo Chen, Dong Sun, Lidai Wang, "Review of photoacoustic imaging for microrobots tracking in vivo [Invited]," Chin. Opt. Lett. 19, 111701 (2021)
Category: Biophotonics
Received: Mar. 30, 2021
Accepted: May. 14, 2021
Published Online: Sep. 6, 2021
The Author Email: Dong Sun (medsun@cityu.edu.hk), Lidai Wang (lidawang@cityu.edu.hk)