Acta Optica Sinica, Volume. 44, Issue 5, 0517002(2024)

Online Detection System of Human Exhaled Nitric Oxide Based on TDLAS Technology

Weijie He1,2, Juncheng Lu2, Lu Gao2, Qiong Wu2, Xiaoyu Wu3, Huagui Nie4, Xiaojing Chen5、**, and Jie Shao2、*
Author Affiliations
  • 1College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, Zhejiang , China
  • 2Key Laboratory of Researching Optical Information Detecting and Display Technology in Zhejiang Province, Zhejiang Normal University, Jinhua 321004, Zhejiang , China
  • 3Zhejiang Jinhua Guangfu Tumor Hospital, Jinhua 321000, Zhejiang , China
  • 4College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, Zhejiang , China
  • 5College of Electrical and Electronic Engineering, Wenzhou University, Wenzhou 325035, Zhejiang , China
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    Figures & Tables(12)
    Absorption spectral lines of NO, CO2, and H2O are distributed
    Schematic diagram of FeNO detection system
    Relationship between modulation amplitude and peak value of second harmonic signal
    Peak value and volume fraction curves of CO2 second harmonic signal based on WMS and DAS technologies
    Relationship between CO2 volume fraction and peak value of second harmonic signal
    Simulation of second harmonic signals for CO2 with a volume fraction of 4% and NO with a volume fraction of 2.0×10-8
    Relationship between NO volume fraction and peak value of second harmonic signal
    Continuous measurement of gas volume fraction variations for 15 min. (a) CO2; (b) NO
    System response curve
    Continuous measurement results of gas volume fraction and Allan variance. (a) CO2; (b) NO
    Curves CO2 and NO volume fractions during single exhalation cycle
    Measurement results of volume fraction of exhaled gas by volunteers. (a) CO2; (b) NO
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    Weijie He, Juncheng Lu, Lu Gao, Qiong Wu, Xiaoyu Wu, Huagui Nie, Xiaojing Chen, Jie Shao. Online Detection System of Human Exhaled Nitric Oxide Based on TDLAS Technology[J]. Acta Optica Sinica, 2024, 44(5): 0517002

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    Paper Information

    Category: Medical optics and biotechnology

    Received: Dec. 1, 2023

    Accepted: Jan. 5, 2024

    Published Online: Mar. 15, 2024

    The Author Email: Chen Xiaojing (chenxj@wzu.edu.cn), Shao Jie (shaojie@zjnu.cn)

    DOI:10.3788/AOS231867

    CSTR:32393.14.AOS231867

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