Label-free fiber nanograting sensor for real-time <i>in situ</i> early monitoring of cellular apoptosis

Danran Li; Nina Wang; Tianyang Zhang; Guangxing Wu; Yifeng Xiong; Qianqian Du; Yunfei Tian; Weiwei Zhao; Jiandong Ye; Shulin Gu; Yanqing Lu; Dechen Jiang; Fei Xu

doi:10.1117/1.AP.4.1.016001

Advanced Photonics, Volume. 4, Issue 1, 016001(2022)

Label-free fiber nanograting sensor for real-time in situ early monitoring of cellular apoptosis

Danran Li^1,2, Nina Wang³, Tianyang Zhang³, Guangxing Wu^1,2, Yifeng Xiong^1,2, Qianqian Du⁴, Yunfei Tian^1,2, Weiwei Zhao³, Jiandong Ye⁴, Shulin Gu⁴, Yanqing Lu^1,2, Dechen Jiang^3、*, and Fei Xu^1,2、*

Author Affiliations

¹Nanjing University, College of Engineering and Applied Sciences, Nanjing, China

²Nanjing University, National Laboratory of Solid State Microstructures, Collaborative Innovation Center of Advanced Microstructures, Nanjing, China

³Nanjing University, School of Chemistry and Chemical Engineering, Nanjing, China

⁴Nanjing University, School of Electronic Science and Engineering, Nanjing, China

show less

References(50)

[1] A. Colom et al. A fluorescent membrane tension probe. Nat. Chem., 10, 1118-1125(2018).

[2] J. S. Donner et al. Mapping intracellular temperature using green fluorescent protein. Nano Lett., 12, 2107-2111(2012).

[3] K. Okabe et al. Intracellular temperature mapping with a fluorescent polymeric thermometer and fluorescence lifetime imaging microscopy. Nat. Commun., 3, 705(2012).

[4] J. M. Yang, H. Yang, L. Lin. Quantum dot nanothermometers reveal heterogeneous local thermogenesis in living cells. ACS Nano, 5, 5067-5071(2011).

[5] X. Chen et al. Imaging the transient heat generation of individual nanostructures with a mechanoresponsive polymer. Nat. Commun., 8, 1498(2017).

[6] G. Kucsko et al. Nanometre-scale thermometry in a living cell. Nature, 500, 54-58(2013).

[7] Z. Chen et al. Single gold@silver nanoprobes for real-time tracing the entire autophagy process at single-cell level. J. Am. Chem. Soc., 137, 1903-1908(2015).

[8] O. A. Savchuk et al. Thermochromic upconversion nanoparticles for visual temperature sensors with high thermal, spatial and temporal resolution. J. Mater. Chem. C, 4, 6602-6613(2016).

[9] X. Zhu et al. Temperature-feedback upconversion nanocomposite for accurate photothermal therapy at facile temperature. Nat. Commun., 7, 10437(2016).

[10] P. C. Wuytens et al. Gold nanodome-patterned microchips for intracellular surface-enhanced Raman spectroscopy. Analyst, 140, 8080-8087(2015).

[11] K. Yum et al. Mechanochemical delivery and dynamic tracking of fluorescent quantum dots in the cytoplasm and nucleus of living cells. Nano Lett., 9, 2193-2198(2009).

[12] T. Vo-Dinh et al. Antibody-based nanoprobe for measurement of a fluorescent analyte in a single cell. Nat. Biotechnol., 18, 764-767(2000).

[13] Q. Yang et al. Fiber-optic-based micro-probe using hexagonal 1-in-6 fiber configuration for intracellular single-cell pH measurement. Anal. Chem., 87, 7171-7179(2015).

[14] R. Yan et al. Nanowire-based single-cell endoscopy. Nat. Nanotechnol., 7, 191-196(2012).

[15] J. Lee et al. Quantitative probing of Cu²⁺ ions naturally present in single living cells. Adv. Mater., 28, 4071-4076(2016).

[16] J. H. Lee et al. Spontaneous internalization of cell penetrating peptide-modified nanowires into primary neurons. Nano Lett., 16, 1509-1513(2016).

[17] X. Cao et al. Single silicon nanowire-based fluorescent sensor for endogenous hypochlorite in an individual cell. Adv. Biosyst., 2, 1800213(2018).

[18] C. Chiappini et al. Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization. Nat. Mater., 14, 532-539(2015).

[19] W. Hong et al. Nanoscale label-free bioprobes to detect intracellular proteins in single living cells. Sci. Rep., 4, 6179(2014).

[20] G. Shambat et al. Single-cell photonic nanocavity probes. Nano Lett., 13, 4999-5005(2013).

[21] A. Meister et al. FluidFM: combining atomic force microscopy and nanofluidics in a universal liquid delivery system for single cell applications and beyond. Nano Lett., 9, 2501-2507(2009).

[22] P. Knittel et al. Focused ion beam-assisted fabrication of soft high-aspect ratio silicon nanowire atomic force microscopy probes. Ultramicroscopy, 179, 24-32(2017).

[23] O. Guillaume-Gentil et al. Tunable single-cell extraction for molecular analyses. Cell, 166, 506-516(2016).

[24] F. Santoro et al. Revealing the cell-material interface with nanometer resolution by focused ion beam/scanning electron microscopy. ACS Nano, 11, 8320-8328(2017).

[25] S. M. Yoo et al. Electrotriggered, spatioselective, quantitative gene delivery into a single cell nucleus by Au nanowire nanoinjector. Nano Lett., 13, 2431-2435(2013).

[26] G. Lu et al. Live-cell SERS endoscopy using plasmonic nanowire waveguides. Adv. Mater., 26, 5124-5128(2014).

[27] P. D. Tovee et al. Nanoscale resolution scanning thermal microscopy using carbon nanotube tipped thermal probes. Phys. Chem. Chem. Phys., 16, 1174-1181(2014).

[28] R. Pan et al. Resistive-pulse sensing inside single living cells. J. Am. Chem. Soc., 142, 5778-5784(2020).

[29] H. Liu et al. A multiparameter pH-sensitive nanodevice based on plasmonic nanopores. Adv. Funct. Mater., 28, 1703847(2018).

[30] Y. Zhang et al. Spearhead nanometric field-effect transistor sensors for single-cell analysis. ACS Nano, 10, 3214-3221(2016).

[31] R. Singhal et al. Multifunctional carbon-nanotube cellular endoscopes. Nat. Nanotechnol., 6, 57-64(2011).

[32] D. Chrétien et al. Mitochondria are physiologically maintained at close to 50°C. PLoS Biol., 16, e2003992(2018).

[33] S. Arai et al. Mitochondria-targeted fluorescent thermometer monitors intracellular temperature gradient. Chem. Commun., 51, 8044-8047(2015).

[34] X. Fan et al. Sensitive optical biosensors for unlabeled targets: a review. Anal. Chim. Acta, 620, 8-26(2008).

[35] J. L. Kou et al. Demonstration of a compact temperature sensor based on first-order Bragg grating in a tapered fiber probe. Opt. Express, 19, 18452-18457(2011).

[36] J. L. Kou et al. Miniaturized fiber taper reflective interferometer for high temperature measurement. Opt. Express, 18, 14245-14250(2010).

[37] Z. Hu, X. Guo, L. Tong. Freestanding nanowire ring laser. Appl. Phys. Lett., 103, 183104(2013).

[38] X. Xing et al. Ultracompact photonic coupling splitters twisted by PTT nanowires. Nano Lett., 8, 2839-2843(2008).

[39] A. Fu et al. Widely tunable distributed Bragg reflectors integrated into nanowire waveguides. Nano Lett., 15, 6909-6913(2015).

[40] R. Röder et al. Ultrafast dynamics of lasing semiconductor nanowires. Nano Lett., 15, 4637-4643(2015).

[41] J. Tatebayashi et al. Room-temperature lasing in a single nanowire with quantum dots. Nat. Photonics, 9, 501-505(2015).

[42] T. K. Kim et al. Physicochemical properties of nucleoli in live cells analyzed by label-free optical diffraction tomography. Cells, 8, 699(2019).

[43] D. R. Li et al. Ethanol gas sensor based on a hybrid polymethyl methacrylate–silica microfiber coupler. J. Lightwave Technol., 36, 2031-2036(2018).

[44] F. Chiavaioli et al. Biosensing with optical fiber gratings. Nanophotonics, 6, 663-679(2017).

[45] S. Cohen-Maslaton et al. Cell and nucleus refractive-index mapping by interferometric phase microscopy and rapid confocal fluorescence microscopy. J. Biophotonics, 13, e202000117(2020).

[46] F. Chiavaioli. Recent development of resonance-based optical sensors and biosensors. Optics, 1, 255-258(2020).

[47] A. Calabuig et al. Investigating fibroblast cells under ‘safe’ and ‘injurious’ blue-light exposure by holographic microscopy. J. Biophotonics, 10, 919-927(2017).

[48] J. J. M. Landry et al. The genomic and transcriptomic landscape of a HeLa cell line. G3-Genes Genom. Genet., 3, 1213-1224(2013).

[49] C. Huang et al. Long-term blue light exposure induces RGC-5 cell death in vitro: involvement of mitochondria-dependent apoptosis, oxidative stress, and MAPK signaling pathways. Apoptosis, 19, 922-932(2014).

[50] T. Erdogan. Fiber grating spectra. J. Lightwave Technol., 15, 1277-1294(1997).

Tools

Get Citation

Copy Citation Text

Danran Li, Nina Wang, Tianyang Zhang, Guangxing Wu, Yifeng Xiong, Qianqian Du, Yunfei Tian, Weiwei Zhao, Jiandong Ye, Shulin Gu, Yanqing Lu, Dechen Jiang, Fei Xu, "Label-free fiber nanograting sensor for real-time in situ early monitoring of cellular apoptosis," Adv. Photon. 4, 016001 (2022)

Download Citation

EndNote(RIS)BibTex Plain Text

Set citation alerts for article

Save article for my favorites

Paper Information

Category: Research Articles

Received: Oct. 26, 2021

Accepted: Dec. 14, 2021

Published Online: Jan. 10, 2022

The Author Email: Jiang Dechen (dechenjiang@nju.edu.cn), Xu Fei (feixu@nju.edu.cn)

DOI:10.1117/1.AP.4.1.016001

Topics

laser devices and laser physics

Lasers and Laser Optics

Laser physics

laser manufacturing

Instrumentation, Measurement and Metrology