Researching | Research on three-dimensional culture and drug screening of tumor cell spheres based on microfluidic chips

Optical Instruments, Volume. 47, Issue 3, 37(2025)

Research on three-dimensional culture and drug screening of tumor cell spheres based on microfluidic chips

Zhiwei XUE and Lulu ZHENG^*

Author Affiliations

School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China

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References (14)

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Figures & Tables(6)

Fig. 1. Chip design and masks

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Fig. 2. Fabrication and structure of microfluidic chips

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Fig. 3. The growth of clumps of tumor cells

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Fig. 4. Staining in single microcavity

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Fig. 5. Three-dimensional image of tumor cell spheres

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Fig. 6. Drug screening results in microfluidic chip and 96-well plate

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Zhiwei XUE, Lulu ZHENG. Research on three-dimensional culture and drug screening of tumor cell spheres based on microfluidic chips[J]. Optical Instruments, 2025, 47(3): 37

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Paper Information

Received: Dec. 19, 2023

Accepted: --

Published Online: Jul. 28, 2025

The Author Email: Lulu ZHENG (llzheng@usst.edu.cn)

DOI:10.3969/j.issn.1005-5630.202312190137

Topics

laser devices and laser physics

Lasers and Laser Optics

laser manufacturing

Instrumentation, Measurement and Metrology