Laser & Optoelectronics Progress, Volume. 58, Issue 10, 1011012(2021)

Research Progress of Super-Resolution Fluorescence Microscopy Based on Quantum Correlation

Wenwen Li1,2 and Zhongyang Wang1、*
Author Affiliations
  • 1Center for Fundamental Interdisciplinary Research, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China
  • 2School of Microelectronics, University of Chinese Academy of Sciences, Beijing 100049, China
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    Figures & Tables(10)
    Principle diagram of STED technology[5]
    Principle diagram of STORM technology[5]. (a) Principle diagram of STORM imaging; (b) process image of STORM imaging
    Principle diagram of SIM technology[5]
    Experimental principle diagram of single photon source judgement [24]. (a) HBT interference experiment; (b) HOM interference experiment
    Principle diagram of super-resolution fluorescence microscopy based on antibunching
    Application of super-resolution fluorescence microscopy based on antibunching in confocal microscopy and wide field microscopy, respectively. (a) Confocal microscopy[52];(b) wide-field microscopy[61]
    Experimental setup and results of GISC camera [75]. (a) Experimental setup of GISC camera; (b) reconstruction results of spectral images
    Principle diagram of GISC-Nanoscopy technology
    Experimental setup and results of GISC-Nanoscopy[83]. (a) Experimental setup of GISC-Nanoscopy; (b) super-resolution imaging of ring with 80 nm spacing; (c) super-resolution imaging of DNA nanometer ruler with 160 nm spacing
    Results of GISC-STORM[83]. (a) Comparison between original position and reconstructed position of simulated fluorescent molecules at density of 50.7 μm-2; (b) ability to identify molecular densities at different SNRs; (c) localization precision of molecules at different SNRs and densities; (d) diffraction-limited wide field image of ring with 60 nm spacing; (e)--(h) sampling frames of ThunderSTORM, CS-STORM and GISC-STORM for resolving ring with 60 nm spacing
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    Wenwen Li, Zhongyang Wang. Research Progress of Super-Resolution Fluorescence Microscopy Based on Quantum Correlation[J]. Laser & Optoelectronics Progress, 2021, 58(10): 1011012

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    Paper Information

    Category: Imaging Systems

    Received: Apr. 3, 2021

    Accepted: Apr. 23, 2021

    Published Online: May. 28, 2021

    The Author Email: Zhongyang Wang (wangzy@sari.ac.cn)

    DOI:10.3788/LOP202158.1011012

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