Chinese Journal of Lasers, Volume. 50, Issue 3, 0307105(2023)

Application of Optical Imaging for Studying Chinese Acupuncture: a Review

Yue Xu1 and Liming Nie2、*
Author Affiliations
  • 1Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China
  • 2Optical Molecular Imaging Laboratory, Research Center of Medical Sciences, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong, China
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    Figures & Tables(6)
    Different imaging technologies for studying acupuncture therapy and their application scope
    Continuous display of gastric laser Doppler blood perfusion images of rats during electroacupuncture (EA)[30]. (a) Before EA stimulation; (b) instant of EA stimulation; (c) EA stimulation for 5 min; (d) EA stimulation for 10 min; (e) 5 min after ceasing EA stimulation; (f) 10 min after ceasing EA stimulation
    Comparison of peak values of group average hemodynamic response between CG and IG for each phase[59]. (a) The first phase (0 week); (b) the second phase (4 weeks); (c) the third phase (8 weeks)
    Maximum amplitude projection (MAP) and corresponding computed vascular centerlines overlaid with segmented volumetric opticalresolution photoacoustic microscopy (OR-PAM) images of GB34, ST36 and non-acupoint sites in the osteoarthritis group (scale bar is 200 μm)[73]
    PAT images of brain under acupuncture on the left or right GB34 point for a representative normal mouse, where the images are given at different time points and the color scale indicates relative strength of photoacoustic signal[77]
    • Table 1. Technical parameters and characteristics of different optical imaging methods and their application scope

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      Table 1. Technical parameters and characteristics of different optical imaging methods and their application scope

      TechnologySpace resolutionTime resolutionPenetration depthApplication scope
      PAM~5 μm~2 s2-3 mmStructural imaging of microvessels;quantitative analysis of hemodynamic parameters
      PACT3-4 mm~100 ms≥40 mmFunctional and structural imaging of vascular in human muscles,visceras and other deep tissues
      fNIRS2 μm≥40 ms~20 mmDetection of cerebral blood and brain dynamics response;verification of acupoint specificity
      LSI2-3 μm≤10 ms≤1 mmMonitoring local tissue blood perfusion and measuring blood supply of lesion site in real-time
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    Yue Xu, Liming Nie. Application of Optical Imaging for Studying Chinese Acupuncture: a Review[J]. Chinese Journal of Lasers, 2023, 50(3): 0307105

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    Paper Information

    Category: Biomedical Optical Imaging

    Received: Aug. 12, 2022

    Accepted: Oct. 21, 2022

    Published Online: Feb. 6, 2023

    The Author Email: Nie Liming (limingnie@gmail.com)

    DOI:10.3788/CJL221142

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