[1] Pron G. Prostate-specific antigen (PSA)-based population screening for prost -ate cancer: an evidence-based analysis[J]. Ontario Health Technology Assessment Series, 15, 1-64(2015).

[2] Scholler N, Urban N. CA125 in ovarian cancer[J]. Biomarkers in Medicine, 1, 513-523(2007).

[3] Ballehaninna U K, Chamberlain R S. The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: an evidence based appraisal[J]. Journal of Gastrointestinal Oncology, 3, 105-119(2012).

[4] Zhao Q Q, Zhan T C, Deng Z A et al. Glycan analysis of colorectal cancer samples reveals stage-dependent changes in CEA glycosylation patterns[J]. Clinical Proteomics, 15, 9(2018).

[5] Tzartzeva K, Obi J, Rich N E et al. Surveillance imaging and alpha fetoprotein for early detection of hepatocellular carcinoma in patients with cirrhosis: a meta-analysis[J]. Gastroenterology, 154, 1706-1718(2018).

[6] Asadzadeh Z, Mansoori B, Mohammadi A et al. microRNAs in cancer stem cells: biology, pathways, and therapeutic opportunities[J]. Journal of Cellular Physiology, 234, 10002-10017(2019).

[7] Ivey K N, Srivastava D. microRNAs as regulators of differentiation and cell fate decisions[J]. Cell Stem Cell, 7, 36-41(2010).

[8] Rodriguez R E, Schommer C, Palatnik J F. Control of cell proliferation by microRNAs in plants[J]. Current Opinion in Plant Biology, 34, 68-76(2016).

[9] Slattery M L, Mullany L E, Sakoda L C et al. Dysregulated genes and miRNAs in the apoptosis pathway in colorectal cancer patients[J]. Apoptosis, 23, 237-250(2018).

[10] Vienberg S, Geiger J, Madsen S et al. microRNAs in metabolism[J]. Acta Physiologica, 219, 346-361(2017).

[11] Andreassen R, Høyheim B. miRNAs associated with immune response in teleost fish[J]. Developmental & Comparative Immunology, 75, 77-85(2017).

[12] Eacker S M, Dawson T M, Dawson V L. Understanding microRNAs in neurodegeneration[J]. Nature Reviews Neuroscience, 10, 837-841(2009).

[13] Small E M, Olson E N. Pervasive roles of microRNAs in cardiovascular biology[J]. Nature, 469, 336-342(2011).

[14] Taganov K D, Boldin M P, Baltimore D. microRNAs and immunity: tiny players in a big field[J]. Immunity, 26, 133-137(2007).

[15] Sharma A R, Sharma G, Lee S S et al. miRNA-regulated key components of cytokine signaling pathways and inflammation in rheumatoid arthritis[J]. Medicinal Research Reviews, 36, 425-439(2016).

[16] Chakraborty C, Chin K Y, Das S. miRNA-regulated cancer stem cells: understanding the property and the role of miRNA in carcinogenesis[J]. Tumor Biology, 37, 13039-13048(2016).

[17] Yang F M, Ning Z Q, Ma L et al. Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts[J]. Molecular Cancer, 16, 138-148(2017).

[18] Yanaihara N, Caplen N, Bowman E et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis[J]. Cancer Cell, 9, 189-198(2006).

[19] Bica-Pop C, Cojocneanu-Petric R, Magdo L et al. Overview upon miR-21 in lung cancer: focus on NSCLC[J]. Cellular and Molecular Life Sciences, 75, 3539-3551(2018).

[20] Wang Z Y, Han J X, Cui Y Z et al. miRNA-21 inhibition enhances RANTES and IP-10 release in MCF-7 via PIAS3 and STAT3 signalling and causes increased lymphocyte migration[J]. Biochemical and Biophysical Research Communications, 439, 384-389(2013).

[21] Guo H L, Ingolia N T, Weissman J S et al. Mammalian microRNAs predominantly act to decrease target mRNA levels[J]. Nature, 466, 835-840(2010).

[22] Niu Y Q, Zhang L M, Qiu H L et al. An improved method for detecting circulating microRNAs with S-Poly(T) Plus real-time PCR[J]. Scientific Reports, 5, 1-10(2015).

[23] Lim L P, Lau N C, Garrett-Engele P et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs[J]. Nature, 433, 769-773(2005).

[24] Lagos-Quintana M, Rauhut R, Lendeckel W et al. Identification of novel genes coding for small expressed RNAs[J]. Science, 294, 853-858(2001).

[25] Bagga S, Bracht J, Hunter S et al. Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation[J]. Cell, 122, 553-563(2005).

[26] Redshaw N, Wilkes T, Whale A et al. A comparison of miRNA isolation and RT-qPCR technologies and their effects on quantification accuracy and repeatability[J]. BioTechniques, 54, 155-164(2013).

[27] Wang Y H, He L L, Huang K J et al. Recent advances in nanomaterial-based electrochemical and optical sensing platforms for microRNA assays[J]. Analyst, 144, 2849-2866(2019).

[28] Tam S, de Borja R, Tsao M S et al. Robust global microRNA expression profiling using next-generation sequencing technologies[J]. Laboratory Investigation, 94, 350-358(2014).

[29] Cohen L, Hartman M R, Amardey-Wellington A et al. Digital direct detection of microRNAs using single molecule arrays[J]. Nucleic Acids Research, 45, e137(2017).