Role and mechanism of trimethylamine oxide in regulating cell ferroptosis through ROS/JNK/GPX4 signaling pathway in slow transmission constipation

CHEN Liping; HUANG Yebao; LI Lingbing; LIU Chunqiang

doi:10.3969/j.issn.1673-534x.2025.03.011

International Journal of Digestive Diseases, Volume. 45, Issue 3, 190(2025)

Role and mechanism of trimethylamine oxide in regulating cell ferroptosis through ROS/JNK/GPX4 signaling pathway in slow transmission constipation

CHEN Liping¹, HUANG Yebao², LI Lingbing¹, and LIU Chunqiang^3、*

Author Affiliations

¹Department of Traditional Chinese Medicine Proctology, Liuzhou People's Hospital Affiliated to Guangxi Medical University, Liuzhou 545006, China

¹General Department of Traditional Chinese Medicine, the Third Clinical Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Liuzhou Traditional Chinese Medicine Hospital, Liuzhou 545001, China

²Department of Traditional Chinese Medicine Proctology, Liuzhou People's Hospital Affiliated to Guangxi Medical University, Liuzhou 545006, China

³Department of Traditional Chinese Medicine Proctology, People's Hospital of Laibin City, Liuzhou 546100, China

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CHEN Liping, HUANG Yebao, LI Lingbing, LIU Chunqiang. Role and mechanism of trimethylamine oxide in regulating cell ferroptosis through ROS/JNK/GPX4 signaling pathway in slow transmission constipation[J]. International Journal of Digestive Diseases, 2025, 45(3): 190

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Paper Information

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Received: May. 28, 2024

Accepted: Aug. 25, 2025

Published Online: Aug. 25, 2025

The Author Email: LIU Chunqiang (825756169@qq.com)

DOI:10.3969/j.issn.1673-534x.2025.03.011

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