Review on Dynamic Scattered Light Measurement in Full-Field Optical Coherence Tomography

Haoying Tian; Fengrui Tang; Wanrong Gao; Yue Zhu

doi:10.3788/CJL202249.0507202

Chinese Journal of Lasers, Volume. 49, Issue 5, 0507202(2022)

Review on Dynamic Scattered Light Measurement in Full-Field Optical Coherence Tomography

Haoying Tian, Fengrui Tang, Wanrong Gao, and Yue Zhu^*

School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China

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Figures & Tables(3)

Fig. 1. Picture of dynamic multi-model imaging device PZT

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Table 1. Ways to eliminate artifacts

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Table 1. Ways to eliminate artifacts

Direction of research	Specific method
Acceleration of imaging speed	Use of high-speed cameras
Acceleration of imaging speed	Instantaneous phase shifting
Algorithm improvement	Riesz transform-based algorithms
	Hilbert transform-based image restoration technology
	Single-step phase-shifting demodulation algorithm based on Hilbert transform
	Singular value decomposition-based image filtering algorithms

Table 2. Research of D-FFOCT inprecision medicine

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Table 2. Research of D-FFOCT inprecision medicine

Time	Authors	Sample	Process	Application	Parameter
2016	Apelian C，Harms F, Thouvenin O, et al.	Cancerous cells in mouse intestine		Diagnose cancer	Axial resolution: 1 μm, imaging depth: 50100 μm
2016	Apelian C，Harms F, Thouvenin O, et al.	Rat liver cells	Introduced an inhibitor of the metabolic chain	Study pathological	Axial resolution: 1 μm, imaging depth: 50100 μm
2016	Leroux C E，Bertillot F，Thouvenin O, et al.	Multicellular aggregates spheroids	Introduced a selective inhibitor of class-II myosins (blebbistatin)	Observe drug effect，diagnose cancer	Depth resolution: 1 μm，isotropic resolution: 1 μm³ (at the central 625 nm wavelength), imaging depth: 60 μm
2017	Apelian C, Gastaud C, Boccara A C.	Mouse intestinal cancer		Diagnose cancer	Depth resolution: 1 μm
2017	Thouvenin O，Apelian C，Nahas A, et al.	A thick coronal section of fresh ex vivo rat brain		Reveal individual neuron shapes and sizes	Imaging depth: 100-200 μm
		Ex vivo subcutaneous pancreatic tumor		Diagnose cancer
		Fresh rat liver		Established more accurate angiogram and lymphogram,
2019	Scholler J，Mazlin V,Thouvenin O, et al.	Macaque cornea	Creating a wound in the epithelial layer	Following in vitro sample evolution over long periods of time	Transverse resolution：0.4 μm, axial resolution: 1 μm, field of view: 390 μm×390 μm
2020	Scholler J，Groux K，Goureau O, et al.	Retinal organoids		Pathological study	Camera frame rate: 100 Hz，transverse resolution: 0.5 μm, axial resolution: 1.7 μm, field of view: 320 μm×320 μm
2020	Yang H P，Zhang S W, Liu P, et al.	Breast and lymph node specimens		Differentiate benign and malignant cells	Axial resolution: 1 μm, imaging depth: 10 μm
2020	El-Sadek I A, Miyazawa A，Shen T W, et al.	Breast adenocarcinoma (MCF7 cell line) spheroids	Use anti-cancer agent (paclitaxel)	Diagnose cancer, drug response evaluation	Axial resolution: 14 μm, lateral resolution: 19 μm

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Haoying Tian, Fengrui Tang, Wanrong Gao, Yue Zhu. Review on Dynamic Scattered Light Measurement in Full-Field Optical Coherence Tomography[J]. Chinese Journal of Lasers, 2022, 49(5): 0507202

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Paper Information

Received: Sep. 23, 2021

Accepted: Nov. 29, 2021

Published Online: Mar. 9, 2022

The Author Email: Zhu Yue (zhuyue@njust.edu.cn)

DOI:10.3788/CJL202249.0507202

Topics

laser devices and laser physics

Lasers and Laser Optics

Laser physics

laser manufacturing

Instrumentation, Measurement and Metrology