High Power Laser and Particle Beams, Volume. 35, Issue 3, 031001(2023)
Skin damage in mice induced by different power densities of 1064 nm laser
Figures & Tables(10)
Fig. 1. Experimental diagram of laser irradiation on the skin of mouse
Fig. 2. Dermoscope images of injury in mice skin at different duration of 1064 nm laser irradiation (400 ms after irradiation; scale bar of dermoscope images: 1 mm)
Fig. 3. Effect of different power density laser irradiation on the skin lesion area of mice
Fig. 4. OCT images of injury in mice skin at different duration of 1064 nm laser irradiation（400 ms after irradiation; scale bar of OCT images：1 mm）
Fig. 5. Effect of laser irradiation with different power density on the depth of the skin damage in mice
Fig. 6. Pathomorphological changes of skin wounds in mice irradiated by 1064nm laser (hematoxylin-eosin staining ×100)
Table 1. Grading of skin lesions in biological skin tissue by 1064 nm laser
View tableView in ArticleTable 1. Grading of skin lesions in biological skin tissue by 1064 nm laser
laser irradiation power density/(W·cm−2) damage appearance ＜958 firstdegree injury Redness at laser irradiation, recovered after some time. 958～1160 seconddegree injury White blisters, deformed and bulging (crumpled) skin around the injury. 1160～1370 thirddegree injury Vaporization of small amounts (or few lesions) on the superficial layer of the skin, blanching skin blisters with a bulging circle around the injury spot, and a shallow pit like focal macule. 1370～2190 fourthdegree injury Through the skin up to the fat layer, superficial vaporization was severe, splashing oil droplets, and around the injury with dark yellow eschar as red pit like spots.
Table 2. The corresponding relationship between the degree of skin thermal injury and laser irradiation power
View tableView in ArticleTable 2. The corresponding relationship between the degree of skin thermal injury and laser irradiation power
laser irradiation power density/(W·cm−2) Ω 374 1.80×10−5 561 3.00×10−4 762 1.9 958 14 1163 27 1369 111 1554 1200 1738 1.90×108 1934 5.50×1014
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Zhibo Liu, Qiong Ma, Xun Zhou, Yu Wei, Hongxiang Kang. Skin damage in mice induced by different power densities of 1064 nm laser[J]. High Power Laser and Particle Beams, 2023, 35(3): 031001
Paper Information
Category: High Power Laser Physics and Technology
Received: Sep. 17, 2022
Accepted: Jan. 11, 2023
Published Online: Mar. 9, 2023
The Author Email: Kang Hongxiang (khx007@163.com)
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