Chinese Journal of Lasers, Volume. 45, Issue 6, 0607003(2018)

Bioluminescence Tomography Based on Multilevel Adaptive Finite Element Method

Junlong Huang and Jingjing Yu*
Author Affiliations
  • School of Physics and Information Technology, Shaanxi Normal University, Xi'an, Shannxi 710119, China
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    Figures & Tables(7)
    (a) An undivided tetrahedral element; (b) two tetrahedral elements obtained by subdividing the midpoint of the longest edge
    (a) Digital mouse model; (b) surface light intensity distribution of the forward grid
    3D view and energy distribution of reconstruction results in single-source case. (a)(b) L1-LS method; (c)(d) L1-LS/MAFEM (α=70%) method; (e)(f) L1-LS/MAFEM (α=40%) method;(g)(h) L1-LS/PRS-MAFEM method
    3D view and energy distribution of reconstruction results in double-source case. (a)(b) L1-LS method; (c)(d) L1-LS/MAFEM (α=70%) method; (e)(f) L1-LS/MAFEM (α=40%) method; (g)(h) L1-LS/PRS-MAFEM method
    • Table 1. Optical parameters of the digital mouse model

      View table

      Table 1. Optical parameters of the digital mouse model

      ItemMuscleHeartStomachLiverKidneyLung
      μa /mm-10.100.210.010.1260.0660.22
      μs /mm-11.202.001.740.5632.252.30
    • Table 2. Reconstruction results of single-source simulation

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      Table 2. Reconstruction results of single-source simulation

      MethodReconstruction position center /mmdLE /mmReconstruction density /(nW·mm-3)
      L1-LS(11.68,11.50,20.29)2.0723.728×10-6
      L1-LS/MAFEM(α=70%)(10.57,10.81,19.53)1.6295.728×10-4
      L1-LS/MAFEM(α=40%)(9.94,12.18,19.27)0.3539.791×10-4
      L1-LS/PRS-MAFEM(9.83,12.13,19.93)0.1989.899×10-4
    • Table 3. Reconstruction results of double light source simulation

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      Table 3. Reconstruction results of double light source simulation

      MethodTargetReconstruction position center /mmdLE /mmReconstruction density /(nW·mm-3 )
      L1-LSS1(10.55,10.31,18.97)2.3781.851×10-5
      S2(11.12,10.89,19.29)2.6779.920×10-6
      L1-LS/MAFEM(α=70%)S1(9.69,9.22,19.49)1.1193.738×10-3
      S2(9.99,11.63,18.71)1.3461.554×10-3
      L1-LS/MAFEM(α=40%)S1(9.51,8.43,18.28)0.8872.103×10-3
      S2(10.21,11.88,19.11)1.3592.260×10-3
      L1-LS/PRS-MAFEMS1(9.51,8.43,18.27)0.8877.698×10-4
      S2(8.83,12.73,19.11)0.3091.078×10-3
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    Junlong Huang, Jingjing Yu. Bioluminescence Tomography Based on Multilevel Adaptive Finite Element Method[J]. Chinese Journal of Lasers, 2018, 45(6): 0607003

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    Paper Information

    Category: biomedical photonics and laser medicine

    Received: Dec. 15, 2017

    Accepted: --

    Published Online: Jul. 5, 2018

    The Author Email: Jingjing Yu (yujj@snnu.edu.cn)

    DOI:10.3788/CJL201845.0607003

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