Visible Chinese Human for Pulmonary Embolism Detection of Monte Carlo Simulation Analysis

Min Wang; Shuo Meng; Jianghui Guo; Ting Li

doi:10.3788/CJL202249.2407103

Chinese Journal of Lasers, Volume. 49, Issue 24, 2407103(2022)

Visible Chinese Human for Pulmonary Embolism Detection of Monte Carlo Simulation Analysis

Min Wang¹, Shuo Meng^1,2, Jianghui Guo^2,3, and Ting Li^2,4、*

Author Affiliations

¹School of Life Sciences, Tiangong University, Tianjin 300387, China

²Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China

³School of Optoelectronic Science and Engineering, University of Electronic Science & Technology of China, Chengdu 611731, Sichuan, China

⁴Chinese Institute for Brain Research, Beijing, Beijing 102206, China

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Figures & Tables(8)

Fig. 1. Description of VCH thoracic model. (a) Thoracic model built with 3D matrix of 436×420×80 voxels; (b) thoracic model is divided into 8 tissue parts

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Fig. 2. Light fluence distributions in thoracic tissue under X-Y-Z field of view. (a) Light fluence in X-Y plane; (b) light fluence in Y-Z plane; (c) light fluence in X-Z plane; (d) three-dimensional space coordinate system used in this study

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Fig. 3. Variation of light fluence in tissue depth. (a) Variation of light fluence from skin to venous blood (the 40th slice); (b) light fluence distribution on the 40th slice

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Fig. 4. Variation of DPF, PPFpa, ratio of PPFpa to DPF with L_SD. (a) DPF exponential growth with the increase of L_SD; (b) variation of PPFpa with L_SD; (c) variation of ratio of PPFpa to DPF with L_SD; (d) proportion of photon absorption in pulmonary artery

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Fig. 5. Linear fitting of normalized light intensity and pulmonary embolism level

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Table 1. Optical properties of thoracic tissue at 800 nm

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Table 1. Optical properties of thoracic tissue at 800 nm

Tissue type	n	μ_a/cm^－1	μ_s/cm^－1	g
Fat	1.33	0.083	134	0.910
Skin	1.37	0.20	73.7	0.715
Lung	1.40	1.00	95.0	0.910
Bone	1.43	0.11	291	0.936
Muscle	1.40	0.54	66.7	0.930
Pulmonary artery vessel wall	1.40	0.92	103	0.930
Arterial blood	1.40	2.33	522	0.990
Venous blood	1.40	2.38	440	0.990

Table 2. Parameters of SaO₂ and SvO₂ for each experimental group
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Table 2. Parameters of SaO₂ and SvO₂ for each experimental group
Group SaO₂/% SvO₂/%
Level Ⅰ 93 71
Level Ⅱ 91 67
Level Ⅲ 89 63
Normal 95 75

Table 3. Proportion of SSD of each tissue at different levels of pulmonary embolism

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Table 3. Proportion of SSD of each tissue at different levels of pulmonary embolism

Level of pulmonary embolism	Proportion of SSD /%
Level of pulmonary embolism	Fat	Skin	Lung	Bone	Muscle	Pulmonary trunk	Arterial blood	Venous blood
Normal	67.398	11.34	0.002	15.92	5.34	0.0131	0	0.004
Level Ⅰ	67.638	11.21	0.002	15.84	5.31	0.0129	0	0.004
Level Ⅱ	67.588	11.27	0.002	15.89	5.25	0.0127	0	0.003
Level Ⅲ	67.867	11.19	0.001	15.65	5.28	0.0126	0	0.002

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Min Wang, Shuo Meng, Jianghui Guo, Ting Li. Visible Chinese Human for Pulmonary Embolism Detection of Monte Carlo Simulation Analysis[J]. Chinese Journal of Lasers, 2022, 49(24): 2407103

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