[1] [1] Global Initiative for Chronic Obstructive Lung Disease．Global strategy for prevention，diagnosis and management of COPD：2024 report [EB/OL]．[2024-01-11] (2025-03-01)．https：//goldcopd.org/2024-gold-report/．

[2] [2] GBD 2019 Diseases and Injuries Collaborators．Global burden of 369 diseases and injuries in 204 countries and territories，1990-2019：a systematic analysis for the Global Burden of Disease Study 2019[J]．Lancet，2020，396 (10258)：1204-1222．

[3] [3] WANG C，XU J Y，YANG L，et al．Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study)：a national cross-sectional study[J]．Lancet，2018，391 (10131)：1706-1717．

[4] [4] ZHONG N S，WANG C，YAO W Z，et al．Prevalence of chronic obstructive pulmonary disease in China：a large，population-based survey [J]．Am J Respir Crit Care Med，2007，176 (8)：753-760．

[5] [5] FANG L W，GAO P，BAO H L，et al．Chronic obstructive pulmonary disease in China：a nationwide prevalence study [J]．Lancet Respir Med，2018，6 (6)：421-430．

[6] [6] YIN P，WU J，WANG L，et al．The burden of COPD in China and its provinces：findings from the global burden of disease study 2019 [J]．Front Public Health．DOI：10.3389/fpubh.2022.859499．

[7] [7] ZHU B F，WANG Y F，MING J，et al．Disease burden of COPD in China：a systematic review [J]．Int J Chron Obstruct Pulmon Dis，2018，13：1353-1364．

[9] [9] FRAGOSO C AVAZ，GILL T M．Respiratory impairment and the aging lung：a novel paradigm for assessing pulmonary function[J]．J Gerontol A Biol Sci Med Sci，2012，67A (3)：264-275．

[10] [10] CELLI B R，HALBERT R J，ISONAKA S，et al．Population impact of different definitions of airway obstruction [J]．Eur Respir J，2003，22 (2)：268-273．

[11] [11] MANNINO D M，BUIST A S．Global burden of COPD：risk factors，prevalence，and future trends [J]．Lancet，2007，370(9589)：765-773．

[12] [12] NTRITSOS G，FRANEK J，BELBASIS L，et al．Gender-specific estimates of COPD prevalence：a systematic review and metaanalysis [J]．Int J Chron Obstruct Pulmon Dis，2018，13：1507-1514．

[13] [13] WHITTAKER H R，PIMENTA J M，JARVIS D，et al．Characteristics associated with accelerated lung function decline in a primary care population with chronic obstructive pulmonary disease[J]．Int J Chron Obstruct Pulmon Dis，2020，15：3079-3091．

[14] [14] FOREMAN M G，ZHANG L N，MURPHY J N，et al．Early-onset chronic obstructive pulmonary disease is associated with female sex，maternal factors，and African American race in the COPD Gene Study [J]．Am J Respir Crit Care Med，2011，184 (4)：414-420．

[16] [16] DEVEREUX G．ABC of chronic obstructive pulmonary disease：definition，epidemiology，and risk factors [J]．BMJ，2006,332 (7550)：1142-1144．

[17] [17] GREENE C M，MARCINIAK S J，TECKMAN J，et al．1-antitrypsin deficiency [J]．Nat Rev Dis Primers，2016，2：16051．

[18] [18] LI J C，ZHU L，WEI Y X，et al．Association between adiposity measures and COPD risk in Chinese adults [J]．Eur Respir J,2020，55 (4)：1901899．

[19] [19] LIN C K，LIN C C．Work of breathing and respiratory drive in obesity [J]．Respirology，2012，17 (3)：402-411．

[20] [20] ZAMMIT C，LIDDICOAT H，MOONSIE I，et al．Obesity and respiratory diseases [J]．Int J Gen Med，2010，3：335-343．

[21] [21] VARELA J E，HINOJOSA M，NGUYEN N．Correlations between intra-abdominal pressure and obesity-related co-morbidities [J]．Surg Obes Relat Dis，2009，5 (5)：524-528．

[22] [22] BARNES P J，SHAPIRO S D，PAUWELS R A．Chronic obstructive pulmonary disease：molecular and cellular mechanisms[J]．Eur Respir J，2003，22 (4)：672-688．

[23] [23] PARK H J，CHO J H，KIM H J，et al．The effect of low body mass index on the development of chronic obstructive pulmonary disease and mortality [J]．J Intern Med，2019，286 (5)：573-582．

[25] [25] BARTAL M．COPD and tobacco smoke [J]．Monaldi Arch Chest Dis，2005，63 (4)：213-225．

[26] [26] SAFITRI W，MARTINI S，ARTANTI K D，et al．Smoking from a younger age is the dominant factor in the incidence of chronic obstructive pulmonary disease：case-control study [J]．Int J Environ Res Public Health，2021，18 (11)：6047．

[27] [27] WALSH M C，SZEFLER S，DAVIS J，et al．Summary proceedings from the bronchopulmonary dysplasia group [J]．Pediatrics，2006，117 (3 Pt 2)：S52-S56．

[28] [28] DIVER W R，JACOBS E J，GAPSTUR S M．Secondhand smoke exposure in childhood and adulthood in relation to adult mortality among never smokers [J]．Am J Prev Med，2018，55 (3)：345-352．

[29] [29] GOODMAN P，AGNEW M，MCCAFFREY M，et al．Effects of the Irish smoking ban on respiratory health of bar workers and air quality in Dublin pubs [J]．Am J Respir Crit Care Med，2007,175 (8)：840-845．

[30] [30] GBD 2013 Mortality and Cause of Death Collaborators．Global，regional，and national age-sex specific all-cause and cause-specific mortality for 240 causes of death，1990 - 2013：a systematic analysis for the Global Burden of Disease Study 2013 [J]．Lancet,2015，385 (9963)：117-171．

[31] [31] GBD 2015 Disease and Injury Incidence and Prevalence Collaborators．Global，regional，and incidencenational，prevalence，and years lived with disability for 310 diseases and injuries，1990-2015：a systematic analysis for the Global Burden of Disease Study 2015 [J]．Lancet，2016，388 (10053)：1545-1602．

[32] [32] LIM S S，VOS T，FLAXMAN A D，et al．A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions，1990 - 2010：a systematic analysis for the Global Burden of Disease Study 2010[J]．Lancet，2012，380 (9859)：2224-2260．

[33] [33] SCHRAUFNAGEL D E，BALMES J R，COWL C T，et al．Air pollution and noncommunicable diseases：a review by the forum of International Respiratory Societies' Environmental Committee，part 1：the damaging effects of air pollution [J]．Chest，2019,155 (2)：409-416．

[35] [35] HAGSTAD S，BACKMAN H，BJERG A，et al．Prevalence and risk factors of COPD among never-smokers in two areas of Sweden—occupational exposure to gas，dust or fumes is an important risk factor [J]．Respir Med，2015，109 (11)：1439-1445．

[36] [36] WRTZ E T，SCHLNSSEN V，MALLING T H，et al．Occupational COPD among Danish never-smokers：a population-based study [J]．Occup Environ Med，2015，72 (6)：456-459．

[37] [37] LAMPRECHT B，MCBURNIE M A，VOLLMER W M，et al．COPD in never smokers：results from the population-based burden of obstructive lung disease study [J]．Chest，2011，139 (4)：752-763．

[38] [38] SYAMLAL G，DONEY B，MAZUREK J M．Chronic obstructive pulmonary disease prevalence among adults who have never smoked，by industry and occupation—United States，2013 - 2017[J]．MMWR Morb Mortal Wkly Rep，2019，68 (13)：303-307.

[39] [39] TORN K，JRVHOLM B．Effect of occupational exposure to vapors，gases，dusts，and fumes on COPD mortality risk among Swedish construction workers：a longitudinal cohort study [J]．Chest，2014，145 (5)：992-997．

[40] [40] DONEY B，HNIZDO E，GRAZIANI M，et al．Occupational risk factors for COPD phenotypes in the Multi-ethnic Study of Atherosclerosis (MESA) Lung Study [J]．COPD，2014，11(4)：368-380．

[41] [41] LU H H，ZENG H H，CHEN Y．Early chronic obstructive pulmonary disease：a new perspective [J]．Chronic Dis Transl Med，2021，7 (2)：79-87．

[42] [42] GUIRGUIS-BLAKE J M，SENGER C A，WEBBER E M，et al．Screening for chronic obstructive pulmonary disease：evidence report and systematic review for the US preventive services task force[J]．JAMA，2016，315 (13)：1378-1393．

[43] [43] OLAK Y，AFZAL S，NORDESTGAARD B G，et al．Prognosis of asymptomatic and symptomatic，undiagnosed COPD in the general population in Denmark：a prospective cohort study [J]．Lancet Respir Med，2017，5 (5)：426-434．

[45] [45] HAN M K，STEENROD A W，BACCI E D，et al．Identifying patients with undiagnosed COPD in primary care settings：insight from screening tools and epidemiologic studies [J]．Chronic Obstr Pulm Dis，2015，2 (2)：103-121．

[46] [46] QU S L，YOU X D，LIU T Y，et al．Cost-effectiveness analysis of COPD screening programs in primary care for high-risk patients in China [J]．NPJ Prim Care Respir Med，2021，31 (1)：28．

[47] [47] FERGUSON G T，ENRIGHT P L，BUIST A S，et al．Office spirometry for lung health assessment in adults：a consensus statement from the National Lung Health Education Program [J]．Respir Care，2000，45 (5)：513-530．

[48] [48] MANGIONE C M，BARRY M J，NICHOLSON W K，et al．Screening for chronic obstructive pulmonary disease：US preventive services task force reaffirmation recommendation statement [J]．JAMA，2022，327 (18)：1806-1811．

[49] [49] MARTINEZ F J，RACZEK A E，SEIFER F D，et al．Development and initial validation of a self-scored COPD population screener questionnaire (COPD-PS) [J]．COPD，2008，5(2)：85-95．

[50] [50] ZHOU Y M，CHEN S Y，TIAN J，et al．Development and validation of a chronic obstructive pulmonary disease screening questionnaire in China [J]．Int J Tuberc Lung Dis，2013，17(12)：1645-1651．

[51] [51] PRICE D B，TINKELMAN D G，NORDYKE R J，et al．Scoring system and clinical application of COPD diagnostic questionnaires[J]．Chest，2006，129 (6)：1531-1539．

[52] [52] ZHANG Q，WANG M，LI X N，et al．Do symptom-based questions help screen COPD among Chinese populations? [J]．Sci Rep，2016，6：30419．

[53] [53] YAWN B P，MAPEL D W，MANNINO D M，et al．Development of the lung function questionnaire (LFQ) to identify airflow obstruction [J]．Int J Chron Obstruct Pulmon Dis，2010，5：1-10．