Fig. 1. Experimental setup and schematic diagram

Fig. 2. MMPD images for several samples. (a) Diattenuation image of linear polarizer oriented at 0°; (b) diattenuation image of linear polarizer oriented at 90°; (c) phase retardance image of quarter-wave plate oriented at 30°

Fig. 3. Microscopic intensity images of HE sections (1000 pixel×1000 pixel). (a1) (a2) Stained and unstained normal skin sections; (b1) (b2) stained and unstained pigmented nevus sections; (c1) (c2) stained and unstained melanoma sections

Fig. 4. MMPD images of unstained skin sections (1000 pixel×1000 pixel). (a1)-(a3) Depolarization image, retardance image, phase and diattenuation image of normal skin; (b1)-(b3) depolarization image, phase retardance image, and diattenuation image of pigmented nevus; (c1)-(c3) depolarization image, phase retardance image, and diattenuation image of melanoma

Fig. 5. Box plots of mean of polarization parameters. (a) Depolarization; (b) retardance; (c) diattenuation

Fig. 6. ROC curves of depolarization. (a) Normal skin and melanoma; (b) normal skin and pigmented nevus; (c) pigmented nevus and melanoma

Fig. 7. ROC curves of phase retardance. (a) Normal skin and melanoma; (b) normal skin and pigmented nevus; (c) pigmented nevus and melanoma

Fig. 8. ROC curves of diattenuation. (a) Normal skin and melanoma; (b) normal skin and pigmented nevus; (c) pigmented nevus and melanoma