The development of perovskite materials in the fields of solar cells and photoelectric detection in recent decades has promoted the relevant materials research in nuclear radiation detection. It is of great scientific challenging to perform compositional design rationally and explore the characteristics of this family of materials by the virtue of their greatly diversified structural tolerance. To optimize their radiation detection performance, the device configuration should be specifically designed in various application scenarios according to the feature of each perovskite semiconductor. This review summarizes the materials characteristics and radiation detection properties of melt growth perovskite semiconductors from the viewpoint of different dimensionality and device design. This review shall provide a reference for the future development of perovskite semiconductors in nuclear radiation detection.