Based on the requirements of the cultivation of innovative talents in new engineering, the previous scientific research results of teachers are applied to the experimental teaching of graduate students, and the headspace solid phase microextraction (HS-SPME) combined with selective ion detection mode GC-MS method is established to accurately analyze 9 odorous substances in water samples from the drinking water source of Taihu Lake, which integrates the sample extraction and purification. This HS-SPME technology has some advantages with low/solvent-free consumption, less sample consumption, high enrichment efficiency and high automation. The experimental teaching gives full play to the advantages of the joint automation of pretreatment technology and instrument analysis, breaks through the tedious steps of traditional sample pretreatment, shows the automatic analysis method of trace organic pollutants in environmental samples, and realizes the in-depth integration of teaching and scientific research.