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Acta Optica Sinica, Volume. 38, Issue 7, 0717002(2018)

Quantitative Optical Detection Method of Hemoglobin Based on BP Neural Network

Shanshan Wang, Kai Huang, Ming Li, Ping Chen*, Weiwei Liu, and Lie Lin
Author Affiliations
  • Institute of Modern Optics, Nankai University, Tianjin 300350, China
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    AbstractGet PDF(in Chinese)
    Figures&Tables (8)
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    References (23)
    Cited By (5)
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    Figures & Tables(8)
    Artificial neuron diagram

    Fig. 1. Artificial neuron diagram

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    Absorption spectrum of hemoglobin in serum

    Fig. 2. Absorption spectrum of hemoglobin in serum

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    Scatter diagram of experimental data

    Fig. 3. Scatter diagram of experimental data

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    Network training results of stochastic gradient descent

    Fig. 4. Network training results of stochastic gradient descent

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    Correlation coefficients of network training using stochastic gradient descent method. (a) Training output; (b) validation output; (c) test output; (d) all output

    Fig. 5. Correlation coefficients of network training using stochastic gradient descent method. (a) Training output; (b) validation output; (c) test output; (d) all output

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    Absorption spectra of serum in healthy person, patients with breast cancer and leukemia

    Fig. 6. Absorption spectra of serum in healthy person, patients with breast cancer and leukemia

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    • Table 1. Partial network training results of stochastic gradient descent method

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      Table 1. Partial network training results of stochastic gradient descent method

      Target data /(g·L-1)Predicted data /(g·L-1)Residual error /(g·L-1)Relative deviation /%
      0.32560.32770.00210.6450
      0.94570.96830.02262.3900
      1.49001.4760-0.01400.9200
      2.35102.3450-0.00600.2760
      0.68270.70630.02363.4570
      1.29801.28900.00900.6934
      0.74200.74920.00720.9704
      0.63370.65920.02554.0240
      0.52080.4947-0.02615.0120
      2.19302.23800.04502.0560
      1.18001.1410-0.03902.5690
      0.99671.02000.02332.3380
      2.27102.2170-0.05402.3600
      1.04101.10200.06105.8880
      1.27301.32900.05604.3740
      Relative deviation /%2.532

    • Table 2. Hemoglobin content in serum of healthy person, patients with breast cancer and leukemia

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      Table 2. Hemoglobin content in serum of healthy person, patients with breast cancer and leukemia

      Serial numberMass concentration of hemoglobin /(g·L-1)
      Healthy personLeukemia patientBreast cancer patient
      10.160.420.78
      20.370.661.08
      30.280.762.00
      40.620.410.94
      50.260.551.27
      60.510.330.43
      70.530.231.39
      80.170.621.97
      90.070.401.50
      100.360.800.58
      110.290.511.46
      120.360.430.56
      130.480.500.46
      140.460.731.82
      150.290.481.70
      160.200.320.62
      170.540.951.58
      180.270.641.64
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    Shanshan Wang, Kai Huang, Ming Li, Ping Chen, Weiwei Liu, Lie Lin. Quantitative Optical Detection Method of Hemoglobin Based on BP Neural Network[J]. Acta Optica Sinica, 2018, 38(7): 0717002

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    Paper Information

    Category: Medical Optics and Biotechnology

    Received: Nov. 24, 2017

    Accepted: --

    Published Online: Sep. 5, 2018

    The Author Email: Chen Ping (chping@nankai.edu.cn)

    DOI:10.3788/AOS201838.0717002

    Topics

    laser devices and laser physics
    Lasers and Laser Optics
    Laser physics
    laser manufacturing
    Instrumentation, Measurement and Metrology