Fig. 1. Structure of large-view field endocytoscopic imaging system with nuclear segmentation function

Fig. 2. Design and assembly of zoom endoscopic objective lens with large-view field. (a) Optical structure; (b) endocytoscopic imaging module; (c) endocytoscopic tip

Fig. 3. Modulation transfer function (MIF) of two imaging modes of zoom endoscopic objective lens with large-view field. (a) Conventional imaging mode; (b) magnifying imaging mode

Fig. 4. Spot diagrams of two imaging modes of zoom endoscopic objective lens with large-view field. (a) Conventional imaging mode; (b) magnifying imaging mode

Fig. 5. Imaging performance experimental system

Fig. 6. Images of resolution target captured by endocytoscopic imaging system with large-view field. (a) Conventional imaging; (b) micro-imaging

Fig. 7. Comparison of photos captured by endocytoscopic imaging system with large-view field and digital pathology section scanner. (a) Photo captured by endocytoscopic imaging system with large-view field; (b) photo captured by digital pathology section scanner

Fig. 8. Training and inference procedures of U-Net nuclear segmentation model

Fig. 9. Structure of U-Net nuclear segmentation model

Fig. 10. Nuclear segmentation results of U-Net model. (a)(c)(e) Original images; (b)(d)(f) segmentation results