Chinese Journal of Lasers, Volume. 52, Issue 3, 0307101(2025)

Measurement Method of Tissue Scattering Coefficient Based on Acousto‐Optic Signals

Chang Zhang1,2, Shiyi Qin1,2, Yao Liu1,2, Fanyu Kong1,2, and Lili Zhu1,2、*
Author Affiliations
  • 1Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350117, Fujian , China
  • 2Fujian Provincial Key Laboratory of Photonics Technology, College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350117, Fujian , China
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    Figures & Tables(14)
    Schematics of photon transport process in biological tissues with and without ultrasound modulation. (a) Photon transport process without ultrasound modulation ; (b) photon transport process with ultrasound modulation
    Schematic diagram of acousto-optic tomography principle
    Diagrams of tissue. (a) Two-dimensional model; (b) grid division
    Ultrasonic source waveform and acousto-optic signal received by detector. (a) Ultrasonic source waveform; (b) acousto-optic signal
    Acousto-optic signal peak-to-peak value versus incident intensity value for different samples in simulation
    Relative intensity and peak-to-peak value of acousto-optic signal versus scattering coefficient in simulation. (a) Relative intensity of acousto-optic signal; (b) peak-to-peak value of acousto-optic signal
    Comparison between measured scattering coefficient and real scattering coefficient under two measurement methods in simulation. (a) Based on relative intensity of acousto-optic signal; (b) based on peak-to-peak value of acousto-optic signal
    Schematic diagram of acousto-optic tomography experimental system
    Acousto-optic signal detected in experiment
    Acousto-optic signal peak-to-peak value versus incident intensity under different sample scattering coefficients in experiment
    Relative intensity and peak-to-peak value of acousto-optic signal versus scattering coefficient in experiment. (a) Relative intensity of acousto-optic signal; (b) peak-to-peak value of acousto-optic signal
    Comparison between measured value and real value of scattering coefficient under two measurement methods in experiment. (a) Based on relative intensity of acousto-optic signal; (b) based on peak-to-peak value of acousto-optic signal
    Measured results by relative intensity of acousto-optic signal after expanding range of sample scattering coefficient. (a) Relative intensity of acousto-optic signal versus scattering coefficient; (b) comparison between measured and actual scattering coefficients
    • Table 1. Initial tissue parameters in simulation

      View table

      Table 1. Initial tissue parameters in simulation

      Initial parameter

      Density ρ /

      (kg·m-3

      Refractive

      index n

      Absorption

      coefficient μa /cm-1

      Scattering

      coefficient μs /cm-1

      Anisotropy

      factor g

      Value10701.335800.95
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    Chang Zhang, Shiyi Qin, Yao Liu, Fanyu Kong, Lili Zhu. Measurement Method of Tissue Scattering Coefficient Based on Acousto‐Optic Signals[J]. Chinese Journal of Lasers, 2025, 52(3): 0307101

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    Paper Information

    Category: Biomedical Optical Imaging

    Received: Aug. 27, 2024

    Accepted: Oct. 9, 2024

    Published Online: Jan. 20, 2025

    The Author Email: Zhu Lili (llzhu@fjnu.edu.cn)

    DOI:10.3788/CJL241170

    CSTR:32183.14.CJL241170

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