Acta Optica Sinica, Volume. 40, Issue 6, 0630001(2020)

Study on Detection of Penicillin Drugs Based on Terahertz Time-Domain Spectroscopy

Xiaoqing Liu, Jiali Yao, Fan Huang, Yongji Liu, Lie Lin, Lu Sun*, and Weiwei Liu
Author Affiliations
  • Tianjin Key Laboratory of Micro-scale Optical Information Science and Technology, Institute of Modern Optics, Nankai University, Tianjin, 300350, China
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    Figures & Tables(9)
    Terahertz time-domain spectroscopy system
    Measurement results of penicillin sodium tablets. (a) Time domain spectra; (b) frequency spectra; (c) absorption spectra
    Measurement results of five penicillin sodium samples. (a) Absorption peak intensity and standard deviation; (b) relationship between absorption peak intensity and mass
    Measurement results of Jin Shining brand amoxicillin drugs. (a) Absorption spectra; (b) absorption peak intensity and standard deviation; (c) relationship between absorption peak intensity and mass
    Measurement results of Ren He brand amoxicillin drugs. (a) Absorption spectra; (b) absorption peak intensity and standard deviation; (c) relationship between absorption peak intensity and mass
    Measurement results of Xiu Zheng brand amoxicillin drugs. (a) Absorption spectra; (b) absorption peak intensity and standard deviation; (c) relationship between absorption peak intensity and mass
    Absorption spectra of three amoxicillin samples
    Two-dimensional structures and molecular calculation results of penicillin sodium and amoxicillin. (a) Two-dimensional chemical structure of penicillin sodium; (b) two-dimensional chemical structure of amoxicillin; (c) theoretical calculation result of penicillin sodium; (d) theoretical calculation result of amoxicillin
    • Table 1. Content of pure amoxicillin from different manufacturers

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      Table 1. Content of pure amoxicillin from different manufacturers

      ManufacturerTotal mass of each capsule /mgMass of pure amoxicillin in each capsule /mgMass fraction of pure amoxicillin /%
      Jin Shining580.5500.086.13
      Ren He288.7250.086.59
      Xiu Zheng293.8125.042.54
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    Xiaoqing Liu, Jiali Yao, Fan Huang, Yongji Liu, Lie Lin, Lu Sun, Weiwei Liu. Study on Detection of Penicillin Drugs Based on Terahertz Time-Domain Spectroscopy[J]. Acta Optica Sinica, 2020, 40(6): 0630001

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    Paper Information

    Category: Spectroscopy

    Received: Nov. 14, 2019

    Accepted: Nov. 29, 2019

    Published Online: Mar. 6, 2020

    The Author Email: Sun Lu (lusun@nankai.edu.cn)

    DOI:10.3788/AOS202040.0630001

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