[1] [1] DOMINGUEZ A, IRUELA-ARISPE ML. Integration of chemo-mechanical signaling in response to fluid shear stress by the endothelium [J]. Curr Opin Cell Biol, 2023, 85:102232.

[2] [2] MOONEN JR, CHAPPELL J, SHI M,et al. KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress [J]. Nat Commun, 2022, 13(1): 4941.

[3] [3] BANERJEE K, LIN YZ, GAHN J,et al. SMAD4 maintains the fluid shear stress set point to protect against arterial-venous malformations [J]. J Clin Invest, 2023, 133(18): e168352.

[4] [4] MEHTA V, PANG KL, ROZBESKY D,et al. The guidance receptor plexin D1 is a mechanosensor in endothelial cells [J]. Nature, 2020, 578 (7794): 290-295.

[5] [5] TAMARGO IA, BAEK KI, KIM Y,et al. Flow-induced reprogramming of endothelial cells in atherosclerosis [J]. Nat Rev Cardiol, 2023, 20 (11): 738-753.

[6] [6] HAMRANGSEKACHAEE M, WEN K, BENCHERIF SA,et al. Atherosclerosis and endothelial mechanotransduction: current knowledge and models for future research [J]. Am J Physiol Cell Physiol, 2023, 324 (2): C488-C504.

[7] [7] KALUCKA J, DE ROOIJ LPMH, GOVEIA J,et al. Singlecell transcriptome atlas of murine endothelial cells [J]. Cell,2020, 180(4): 764-779.

[8] [8] DUMAS SJ, META E, BORRI M,et al. Phenotypic diversity and metabolic specialization renal endothelial cells [J]. Nat Rev Nephrol, 2021, 17 (7): 441-464.

[9] [9] FALKENBERG KD, ROHLENOVA K, LUO YL,et al. The metabolic engine of endothelial cells [J]. Nat Metab, 2019,1 (10): 937-946.

[10] [10] FACCHINELLO N, ASTONE M, AUDANO M,et al. Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix composition [J]. Nat Metab, 2022, 4(1): 123-140.

[11] [11] HASAN SS, FISCHER A. The endothelium: an active regulator of lipid and glucose homeostasis [J]. Trends Cell Biol, 2021, 31 (1): 37-49.

[12] [12] VEYS K, FAN Z, GHOBRIAL M,et al. Role of the GLUT1 glucose transporter in postnatal CNS angiogenesis and blood-brain barrier integrity [J]. Circ Res, 2020, 127 (4): 466-482.

[13] [13] KOCH PS, LEE KH, GOERDT S,et al. Angiodiversity and organotypic functions of sinusoidal endothelial cells [J]. Angiogenesis, 2021, 24 (2): 289-310.

[14] [14] INVERSO D, SH JJ, LEE KH,et al. A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver [J]. Dev Cell, 2021, 56(11): 1677-1693.

[15] [15] KAFFE E, ROULIS M, ZHAO J,et al. Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions [J]. Cell, 2023, 186(18): 3793-3809.

[16] [16] ZHOU BS, MAGANA L, HONG ZG,et al. The angiocrine Rspondin3 instructs interstitial macrophage transition via metabolic-epigenetic reprogramming and resolves inflammatory injury [J]. Nat Immunol, 2020, 21(11): 1430-1443.

[17] [17] DI MARCO B, CROUCH EE, SHAH B,et al. Reciprocal interaction between vascular filopodia and neural stem cells shapes neurogenesis in the ventral telencephalon [J]. Cell Rep, 2020, 33(2): 108256.

[18] [18] LEE HW, XU YY, ZHU XL,et al. Endothelium-derived lactate is required for pericyte function and blood-brain barrier maintenance [J]. EMBO J, 2022, 41(9): e109890.

[19] [19] WENZEL J, HANSEN CE, BETTON C,et al. Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice [J]. Proc Natl Acad Sci U S A, 2020, 117(3): 1753-1761.

[20] [20] LIU XL, DE LA CRUZ E, GU XW,et al. Lymphoangiocrine signals promote cardiac growth and repair [J]. Nature, 2020,588(7839): 705-711.

[21] [21] KIM H, WANG MQ, PAIK DT. Endothelial-myocardial angiocrine signaling in heart development [J]. Front Cell Dev Biol, 2021, 9: 697130.

[22] [22] LI LQ, LIU Q, SHANG TY,et al. Aberrant activation of Notch1 signaling in glomerular endothelium induces albuminuria [J]. Circ Res, 2021, 128 (5): 602-618.

[23] [23] LOVISA S, FLETCHER-SANANIKONE E, SUGIMOTO H,et al. Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis [J]. Sci Signal, 2020,13(635): eaaz2597.

[24] [24] CAPORARELLO N, LIGRESTI G. Vascular contribution to lung repair and fibrosis [J]. Am J Respir Cell Mol Biol, 2023,69(2): 135-146.

[25] [25] ALSINA-SANCHIS E, MULFARTH R, FISCHER A. Control of tumor progression by angiocrine factors [J]. Cancers (Basel), 2021, 13 (11): 2610.

[26] [26] TAVORA B, MEDERER T, WESSEL KJ,et al. Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis [J]. Nature, 2021, 586 (7828): 299-304.

[27] [27] ESPOSITO M, MONDAL N, GRECO TM,et al. Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis [J]. Nat Cell Biol, 2019, 21 (5): 627-639.

[28] [28] CARLSON P, DASGUPTA A, GRZELAK CA,et al. Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy [J]. Nat Cell Biol, 2019, 21 (2):238-250.

[29] [29] LEE HJ, LEE J, YANG MJ,et al. Endothelial cell-derived stem cell factor promotes lipid accumulation through c-Kit-mediated increase of lipogenic enzymes in brown adipocytes [J]. Nat Commun, 2023, 14 (1): 2754.

[30] [30] MONELLI E, VILLACAMPA P, ZABALA-LETONA A,et al. Angiocrine polyamine production regulates adiposity [J]. Nat Metab, 2022, 4(3): 327-343.

[31] [31] FISCHER AW, JAECKSTEIN MY, GOTTSCHLING K,et al. Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation[J]. Cell Metab, 2021, 33 (3): 547-564.

[32] [32] BONDAREVA O, RODRIGUEZ-AGUILERA JR, OLIVEIRA F,et al. Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity [J]. Nat Metab, 2022, 4(11):1591-1610.