Chinese Journal of Lasers, Volume. 48, Issue 16, 1607001(2021)

Reconstruction Algorithm Based on a Virtual Parallel-Projection Model for Photoacoustic Tomography Using an Ultrasonic Transducer with a Large Active Surface

Jiao Li1,2、*, Shichao Miao1, Shaoze Song1, Tong Lu1, Tingting Chen1, and Feng Gao1,2
Author Affiliations
  • 1College of Precision Instruments and Opto-Electronic Engineering, Tianjin University, Tianjin 300072, China
  • 2Tianjin Key Laboratory of Biomedical Detecting Techniques and Instruments, Tianjin 300072, China
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    Figures & Tables(11)
    Schematic of photoacoustic tomography system with multi-view light-sheet illuminations
    Discretization of the forward model in reconstruction procedures and the schematic of calculating the minimum rotation radius of the transducer. (a) Discretization of the forward model; (b) calculating the minimum rotation radius of the transducer
    Models of virtual parallel-projection and linear interpolation. (a) Discretization of the forward model by MB-VP; (b) interpolation schematic of the weight between each point on parallel-projection line and four adjacent points
    Results of numerical simulation. (a) Exact image; (b) reconstructed result by MB method; (c) reconstructed result by MB-SE method; (d) reconstructed result by MB-VP method; (e) profile line
    Profiles along #1, #2, #3,#4, and #5 lines in Fig. 4(e). (a) Profile along #1 line; (b)--(e) profiles along #2,#3,#4, and #5 lines
    MB-SE reconstructed images of microsphere with a distance of 6 mm from the center. (a) Seven surface elements; (b) fifteen surface elements
    Experimental results of phantom. (a) Reconstructed result by MB; (b) reconstructed result by MB-SE; (c) reconstructed result by MB-VP; (d)--(f) profiles of P1, P2, and P3 along x-axis, respectively
    Reconstructed results of in vivo mouse. (a) MB; (b) MB-SE; (c) MB-VP; (d)--(f) zoom-in images of the dotted rectangular areas
    • Table 1. FWHM of four microspheres along x-axis

      View table

      Table 1. FWHM of four microspheres along x-axis

      No.FWHM /μm
      ExactMBMB-SEMB-VP
      #2278267275275
      #3278288285280
      #4278645317297
      #52781104391344
    • Table 2. Difference in modeling costs of MB-SE and MB-VP methods

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      Table 2. Difference in modeling costs of MB-SE and MB-VP methods

      Computing costMB-SEMB-SEMB-SEMB-SEMB-SEMB-VP
      Element79111315--
      Memory /GB8.7110.3511.8313.1914.441.59
      Run-time /s262.13341.14420.09499.38737.2039.29
    • Table 3. FWHM of microspheres in phantom experiments

      View table

      Table 3. FWHM of microspheres in phantom experiments

      Microspheres No.FWHM /μm
      MB-SEMB-VP
      P1345294
      P2352295
      P3373362
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    Jiao Li, Shichao Miao, Shaoze Song, Tong Lu, Tingting Chen, Feng Gao. Reconstruction Algorithm Based on a Virtual Parallel-Projection Model for Photoacoustic Tomography Using an Ultrasonic Transducer with a Large Active Surface[J]. Chinese Journal of Lasers, 2021, 48(16): 1607001

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    Paper Information

    Category: biomedical photonics and laser medicine

    Received: Dec. 28, 2020

    Accepted: Feb. 22, 2021

    Published Online: Jul. 30, 2021

    The Author Email: Jiao Li (jiaoli@tju.edu.cn)

    DOI:10.3788/CJL202148.1607001

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