Acta Laser Biology Sinica, Volume. 32, Issue 4, 368(2023)

Bioinformatics Analysis of Human SIRT1 Gene Promoter and Encoding Protein

WANG Dao1, CHEN Jianlin1, LIU Wenbin2, LIU Dan1, and SONG Tian1
Author Affiliations
  • 1[in Chinese]
  • 2[in Chinese]
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    References(35)

    [1] [1] YANG Y, LIU Y, WANG Y, et al. Regulation of SIRT1 and its roles in inflammation[J] . Frontiers in Immunology, 2022, 13: 831168.

    [2] [2] KANE A E, SINCLAIR D A. Sirtuins and NAD+ in the develop-ment and treatment of metabolic and cardiovascular diseases[J] . Circulation Research, 2018, 123(7): 868-885.

    [3] [3] CHEN Y, ZHOU D, FENG Y, et al. Association of sirtuins (SIRT1-7) with lung and intestinal diseases[J] . Molecular and Cellular Biochemistry, 2022, 477(11): 2539-2552.

    [4] [4] D’ANGELO S, MELE E, DI FILIPPO F, et al. Sirt1 activity in the brain: simultaneous effects on energy homeostasis and repro-duction[J] . International Journal of Environmental Research and Public Health, 2021, 18(3): 1243.

    [5] [5] ALVES-FERNANDES D K, JASIULIONIS M G. The role of SIRT1 on DNA damage response and epigenetic alterations in can-cer[J] . International Journal of Molecular Science, 2019, 20(13): 3153.

    [6] [6] SINGH V, UBAID S. Role of silent information regulator 1 (SIRT1) in regulating oxidative stress and inflammation[J] . In-flammation, 2020, 43(5): 1589-1598.

    [8] [8] CHEN H, LIN X, YI X, et al. SIRT1-mediated p53 deacetylation inhibits ferroptosis and alleviates heat stress-induced lung epithe-lial cells injury[J] . International Journal of Hyperthermia, 2022, 39(1): 977-986.

    [9] [9] DE GREGORIO E, COLELL A, MORALES A, et al. Relevance of SIRT1-NF-κB axis as therapeutic target to ameliorate inflam-mation in liver disease[J] . International Journal of Molecular Sci-ence, 2020, 21(11): 3858.

    [10] [10] MAHMOUD A M, ABD ELGHAFAR O A M, ALZOGHAIBI M A, et al. Agomelatine prevents gentamicin nephrotoxicity by attenuat-ing oxidative stress and TLR-4 signaling, and upregulating PPARγ and SIRT1[J] . Life of Science, 2021, 278: 119600.

    [13] [13] BORNEMAN A R, GIANOULIS T A, ZHANG Z D, et al. Diver-gence of transcription factor binding sites across related yeast spe-cies[J] . Science, 2007, 317(5839): 815-819.

    [14] [14] AKTAR S, SASAKI H, UNOKI M. Identification of ZBTB24 pro-tein domains and motifs for heterochromatin localization and tran-scriptional activation[J] . Genes to Cells, 2019, 24(11): 746-755.

    [15] [15] AREFINIA N, YAGHOUBI R, RAMEZANI A, et al. Association of IFITM1 promoter methylation with severity of SARS-CoV-2 infection[J] . Clinic Laboratory, 2023, 69(4): 6-22.

    [16] [16] MENG L, FENG B, LUAN L, et al. MeCP2 inhibits ischemic neu-ronal injury by enhancing methylation of the FOXO3a promoter to repress the SPRY2-ZEB1 axis[J] . Experimental& Molecular Medicine, 2022, 54(8): 1076-1085.

    [17] [17] PANG S, ZHANG Z, ZHOU Y, et al. Genetic variants of SIRT1 gene promoter in type 2 diabetes[J] . International Jour-nal of Endocrinology, 2023, 2023: 6919275.

    [18] [18] RAI E, SHARMA S, KAUL S, et al. The interactive effect of SIRT1 promoter region polymorphism on type 2 diabetes suscepti-bility in the North Indian population[J] . PLoS One, 2012, 7(11): e48621.

    [19] [19] PENG Y, ZHANG G, TANG H, et al. Influence of SIRT1 poly-morphisms for diabetic foot susceptibility and severity[J] . Medi-cine (Baltimore), 2018, 97(28): e11455.

    [21] [21] CONSIGLIO C R, JULIANA DA SILVEIRA S, MONTICIELO O A, et al. SIRT1 promoter polymorphisms as clinical modifiers on systemic lupus erythematosus[J] . Molecular Biology Reports, 2014, 41(7): 4233-4239.

    [22] [22] YANG G, COLLINS J M, RAFIEE R, et al. SIRT1 gene SNP rs932658 is associated with medication-related osteonecrosis of the jaw[J] . Journal of Bone and Mineral Research, 2021, 36(2): 347-356.

    [23] [23] WANG G, XIE X, YUAN L, et al. Resveratrol ameliorates rheu-matoid arthritis via activation of SIRT1-Nrf2 signaling pathway[J] . Biofactors, 2020, 46(3): 441-453.

    [24] [24] ZHANG K, PAN X, ZHENG J, et al. SIRT1 protects against aortic dissection by regulating AP-1/decorin signaling-mediated PDCD4 activation[J] . Molecular Biology Reports, 2020, 47(3): 2149-2159.

    [25] [25] WAHAB F, RODRIGUEZ POLO I, BEHR R. SIRT1 expression and regulation in the primate testis[J] . International Journal of Molecular Science, 2021, 22(6): 3207.

    [26] [26] LEE Y H, KIM S J, SURH Y J. Role of post-translational modi-fication of silent mating type information regulator 2 homolog 1 in cancer and other disorders[J] . Journal of Cancer Prevention, 2022, 27(3): 157-169.

    [27] [27] LEEY H, KIM S J, FANG X, et al. JNK-mediated Ser27 phos-phorylation and stabilization of SIRT1 promote growth and pro-gression of colon cancer through deacetylation-dependent activa-tion of Snail[J] . Molecular Oncology, 2022, 16(7): 1555-1571.

    [28] [28] MAHMUD Z, GOMES A R, LEE H J, et al. EP300 and SIRT1/6 co-regulate lapatinib sensitivity via modulating FOXO3-acety-lation and activity in breast cancer[J] . Cancers (Basel), 2019, 11(8): 1067.

    [29] [29] WEN Y, HUANG H, HUANG B, et al. Hsa-miR-34a-5p regulates the SIRT1/TP53 axis in prostate cancer[J] . American Journal of Translational Research, 2022, 14(7): 4493-4504.

    [30] [30] MAIESE K. Moving to the rhythm with clock (circadian) genes, autophagy, mTOR, and SIRT1 in degenerative disease and cancer[J] . Current Neurovascular Research, 2017, 14(3): 299-304.

    [31] [31] WANG R H, ZHAO T, CUI K, et al. Negative reciprocal regula-tion between Sirt1 and Per2 modulates the circadian clock and aging[J] . Science Reports, 2016, 6: 28633.

    [32] [32] CHUNG J Y, CHEN H, ZIRKIN B. Sirt1 and Nrf2: regulation of leydig cell oxidant/antioxidant intracellular environment and steroid formation[J] . Biology of Reproduction, 2021, 105(5): 1307-1316.

    [33] [33] ZHANG Y, LI T, PAN M, et al. SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism[J] . Journal of Translational Medicine, 2022, 20(1): 222.

    [34] [34] ONG A L C, RAMASAMY T S. Role of sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming[J] . Ageing Re-search Reviews, 2018, 43: 64-80.

    [35] [35] IMPERATORE F, MAURIZIO J, VARGAS AGUILAR S, et al. SIRT1 regulates macrophage self-renewal[J] . EMBO Journal, 2017, 36(16): 2353-2372.

    [36] [36] REN H, SHAO Y, WU C, et al. Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathway[J] . Molecular and Cellular Endo-crinology, 2020, 500: 110628.

    [37] [37] YANG M, CUI Y, SONG J, et al. Mesenchymal stem cell-condi-tioned medium improved mitochondrial function and alleviated inflammation and apoptosis in non-alcoholic fatty liver disease by regulating SIRT1[J] . Biochemical and Biophysical Research Communications, 2021, 546: 74-82.

    [38] [38] DILMAC S, KUSCU N, CANER A, et al. SIRT1/FOXO signaling pathway in breast cancer progression and metastasis[J] . Interna-tional Journal of Molecular Sciences, 2022, 23(18): 10227.

    [39] [39] CHEN C C, KUO C H, LEUYL, et al. Corylin reduces obesity and insulin resistance and promotes adipose tissue browning through SIRT-1 and β3-AR activation[J] . Pharmacological Re-search, 2021, 164: 105291.

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    WANG Dao, CHEN Jianlin, LIU Wenbin, LIU Dan, SONG Tian. Bioinformatics Analysis of Human SIRT1 Gene Promoter and Encoding Protein[J]. Acta Laser Biology Sinica, 2023, 32(4): 368

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    Paper Information

    Received: Apr. 18, 2023

    Accepted: --

    Published Online: Jan. 26, 2024

    The Author Email:

    DOI:10.3969/j.issn.1007-7146.2023.04.010

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