[1] Geiger B, Bershadsky A, Pankov R et al. Transmembrane crosstalk between the extracellular matrix and the cytoskeleton[J]. Nature Reviews Molecular Cell Biology, 2, 793-805(2001).

[2] Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression[J]. Nature Reviews Cancer, 2, 161-174(2002).

[3] Abbott N J, Rönnbäck L, Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier[J]. Nature Reviews Neuroscience, 7, 41-53(2006).

[4] Discher D E, Mooney D J, Zandstra P W. Growth factors, matrices, and forces combine and control stem cells[J]. Science, 324, 1673-1677(2009).

[5] Zamir E, Katz M, Posen Y et al. Dynamics and segregation of cell-matrix adhesions in cultured fibroblasts[J]. Nature Cell Biology, 2, 191-196(2000).

[6] Butcher D T, Alliston T, Weaver V M. A tense situation: forcing tumour progression[J]. Nature Reviews Cancer, 9, 108-122(2009).

[7] Lin H X, Zuo N, Zhuo S M et al. Application of multiphoton microscopy in disease diagnosis[J]. Chinese Journal of Lasers, 45, 0207014(2018).

[8] Li H, Xia X Y, Chen T et al. Applications of two-photon excitation fluorescence lifetime imaging in tumor diagnosis[J]. Chinese Journal of Lasers, 45, 0207010(2018).

[9] Zipfel W R, Williams R M, Webb W W. Nonlinear magic: multiphoton microscopy in the biosciences[J]. Nature Biotechnology, 21, 1369-1377(2003).

[10] Zemel A, Rehfeldt F. Brown A E X, et al. Optimal matrix rigidity for stress-fibre polarization in stem cells[J]. Nature Physics, 6, 468-473(2010).

[11] Barnes C, Speroni L, Quinn K P et al. From single cells to tissues: interactions between the matrix and human breast cells in real time[J]. PLoS One, 9, e93325(2014).

[12] Schriefl A J, Zeindlinger G, Pierce D M et al. Determination of the layer-specific distributed collagen fibre orientations in human thoracic and abdominal aortas and common iliac arteries[J]. Journal of the Royal Society Interface, 9, 1275-1286(2012).

[13] Altendorf H, Decencière E, Jeulin D et al. Imaging and 3D morphological analysis of collagen fibrils[J]. Journal of Microscopy, 247, 161-175(2012).

[14] Napadow V J, Chen Q, Mai V et al. Quantitative analysis of three-dimensional-resolved fiber architecture in heterogeneous skeletal muscle tissue using NMR and optical imaging methods[J]. Biophysical Journal, 80, 2968-2975(2001).

[15] Bancelin S, Nazac A, Ibrahim B H et al. Determination of collagen fiber orientation in histological slides using Mueller microscopy and validation by second harmonic generation imaging[J]. Optics Express, 22, 22561(2014).

[16] Sivaguru M, Durgam S, Ambekar R et al. Quantitative analysis of collagen fiber organization in injured tendons using Fourier transform-second harmonic generation imaging[J]. Optics Express, 18, 24983(2010).

[17] Quinn K P, Georgakoudi I. Rapid quantification of pixel-wise fiber orientation data in micrographs[J]. Journal of Biomedical Optics, 18, 046003(2013).

[18] Lau T Y, Ambekar R, Toussaint K C. Quantification of collagen fiber organization using three-dimensional Fourier transform-second-harmonic generation imaging[J]. Optics Express, 20, 21821-21832(2012).

[19] Liu Z Y, Pouli D, Sood D et al. Automated quantification of three-dimensional organization of fiber-like structures in biological tissues[J]. Biomaterials, 116, 34-47(2017).

[20] Liu Z Y, Quinn K P, Speroni L et al. Rapid three-dimensional quantification of voxel-wise collagen fiber orientation[J]. Biomedical Optics Express, 6, 2294-2310(2015).

[21] Quinn K P, Golberg A, Broelsch G F et al. An automated image processing method to quantify collagen fibre organization within cutaneous scar tissue[J]. Experimental Dermatology, 24, 78-80(2015).

[22] Quinn K P, Sullivan K E, Liu Z Y et al. Optical metrics of the extracellular matrix predict compositional and mechanical changes after myocardial infarction[J]. Scientific Reports, 6, 35823(2016).

[23] Loeser R F, Goldring S R, Scanzello C R et al. Osteoarthritis: a disease of the joint as an organ[J]. Arthritis & Rheumatism, 64, 1697-1707(2012).

[24] Mingalone C K, Liu Z Y, Hollander J M et al. Bioluminescence and second harmonic generation imaging reveal dynamic changes in the inflammatory and collagen landscape in early osteoarthritis[J]. Laboratory Investigation, 98, 656-669(2018).

[25] Nieminen M T, Rieppo J, Töyräs J et al. T2 relaxation reveals spatial collagen architecture in articular cartilage: a comparative quantitative MRI and polarized light microscopic study[J]. Magnetic Resonance in Medicine, 46, 487-493(2001).

[26] Ambekar R, Lau T Y, Walsh M et al. Quantifying collagen structure in breast biopsies using second-harmonic generation imaging[J]. Biomedical Optics Express, 3, 2021-2035(2012).

[27] Schnelldorfer T, Ware A L, Sarr M G et al. Long-term survival after pancreatoduodenectomy for pancreatic adenocarcinoma[J]. Annals of Surgery, 247, 456-462(2008).

[28] Whatcott C J, Diep C H, Jiang P et al. Desmoplasia in primary tumors and metastatic lesions of pancreatic cancer[J]. Clinical Cancer Research, 21, 3561-3568(2015).

[29] Tang-Schomer M D, White J D, Tien L W et al. Bioengineered functional brain-like cortical tissue[J]. Proceedings of the National Academy of Sciences of the United States of America, 111, 13811-13816(2014).

[30] Hirokawa N, Niwa S, Tanaka Y. Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease[J]. Neuron, 68, 610-638(2010).

[31] Sundarakrishnan A, Zukas H, Coburn J et al. Bioengineered in vitro tissue model of fibroblast activation for modeling pulmonary fibrosis[J]. ACS Biomaterials Science & Engineering, 5, 2417-2429(2019).

[32] Liu Z Y, Speroni L, Quinn K P et al. 3D organizational mapping of collagen fibers elucidates matrix remodeling in a hormone-sensitive 3D breast tissue model[J]. Biomaterials, 179, 96-108(2018).

[33] Dhimolea E, Maffini M V, Soto A M et al. The role of collagen reorganization on mammary epithelial morphogenesis in a 3D culture model[J]. Biomaterials, 31, 3622-3630(2010).

[34] Birk J W, Tadros M, Moezardalan K et al. Second harmonic generation imaging distinguishes both high-grade dysplasia and cancer from normal colonic mucosa[J]. Digestive Diseases and Sciences, 59, 1529-1534(2014).