Chinese Journal of Lasers, Volume. 50, Issue 9, 0907105(2023)
High‑Accuracy Quantitative Functional Imaging Technique for Retinal Opto‑Physiology with Optical Coherence Tomography
Fig. 1. Visual fields of patients with retinopathy and structure of retina. (a) Visual manifestations of normal retina and three common blinding retinal diseases; (b) multilayered structure of retina[3]
Fig. 2. Expressions of function signals in human cone and mouse rod photoreceptors. (a) Optical stimulus-induced cone outer segment optical path length change and its projection on retina enface with stimulus pattern shown in lower left inset[50]; (b) square-shape stimulus-induced cone outer segment optical path length change and (c) temporal measurement results[50]; (d) dark-adapted mouse retina OCT image[51]; (e) changes of retinal contour in mice within 2 min after light stimulation[51]; (f) 3-5 times scattering enhancement in rod outer segments[51]; (g) scattering changes of Bruch’s membrane and sclera[51]; (h) ~2 μm position changes of external limiting membrane and inner/outer segment junction[51]
Fig. 3. Nanoscale visual photophysiological measurements of individual cone cells in human eye by AO-OCT[61]. (a) Detecting outer segment optical path length change (∆OPL) of dark-adapted cone cell stimulated with visible flash using phase information by AO-OCT; (b) en face intensity image of cone mosaic; (c) responses of cone cells to 637 nm visible light stimulus; (d) classifying cone cells into three types according to intensity of ∆OPL
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Yanhong Ma, Pengfei Zhang. High‑Accuracy Quantitative Functional Imaging Technique for Retinal Opto‑Physiology with Optical Coherence Tomography[J]. Chinese Journal of Lasers, 2023, 50(9): 0907105
Category: Biomedical Optical Imaging
Received: Oct. 8, 2022
Accepted: Nov. 25, 2022
Published Online: Apr. 25, 2023
The Author Email: Zhang Pengfei (pfzhang@dlut.edu.cn)