Chinese Journal of Lasers, Volume. 52, Issue 3, 0307207(2025)

Finite Element Analysis of Corneal Elasticity After Small Incision Lenticule Extraction Surgery Evaluated by Optical Coherence Elastography

Jixi Guo, Lihua Fang*, Gang Shi, Ruixuan Yu, Yi Zhang, Xinchao Wang, and Xuyang Zhang
Author Affiliations
  • Key Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang 330063, Jiangxi , China
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    Figures & Tables(11)
    Postoperative geometric model and mesh generation. (a) Postoperative geometric model; (b) mesh generation of the postoperative geometric model
    Finite element simulation of shear wave propagation in rabbit eyes cornea after SMILE
    Phase velocity calculation of the shear wave in rabbit eyes cornea after SMILE (using -6 D as an example). (a) Wave number-frequency map; (b) phase velocity dispersion curve
    Variation in shear wave velocity and elastic modulus with corrected refraction. (a) Variation in shear wave velocity; (b) variation in elastic modulus
    Relationship between cutting variables and variation in shear wave velocity with corneal cap thicknesses. (a) Relationship between cutting variables; (b) variation in shear wave velocity
    Variation in elastic modulus with corneal cap thicknesses for different corrected refractions. (a) -3 D; (b) -6 D
    ARF-OCE experiment results of cornea for in vivo rabbit eyes after SMILE. (a) Two-dimensional OCT structure diagram; (b)‒(e) elastic wave propagation maps; (f) spatio-temporal Doppler displacement diagram of elastic wave
    Phase velocity calculation of the elastic wave in cornea for in vivo rabbit eyes after SMILE. (a) Wave number-frequency map; (b) phase velocity dispersion curve
    • Table 1. Geometric parameters of the eyeball model

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      Table 1. Geometric parameters of the eyeball model

      ParameterValue
      CCT /μm338
      Axial length /mm16.8495
      Rf(x)  /mm6.78 (anterior)
      6.33 (posterior)
      Rf(y) /mm6.73 (anterior)
      6.14 (posterior)
      Rf(z) /mm6.75 (anterior)
      6.23 (posterior)
    • Table 2. Surgical simulation parameters of rabbit eyes

      View table

      Table 2. Surgical simulation parameters of rabbit eyes

      Case

      Preoperative

      CCT /μm

      Corneal cap

      thickness /μm

      Refraction /D

      Postoperative

      CCT /μm

      Lenticule

      thickness /μm

      RST /μm
      Case 133812003380338
      Case 2132414204
      Case 3230929189
      Case 4329543175
      Case 5427858160
      Case 6526672146
      Case 7625187131
      Case 833880329543215
      Case 9160135
      Case 1033880625187171
      Case 1116091
    • Table 3. Material parameters in the model

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      Table 3. Material parameters in the model

      RegionMaterial model typeConstitutive parameter
      CorneaHyperelasticity

      G1=466.18 Pa

      α1=42.85

      G2=466.19 Pa

      α2=42.36

      ρ1=1062 kg/m3

      ScleraLinear elasticity

      E2=195.27 kPa

      ρ2=1243 kg/m3

      ʋ2=0.495

      LensLinear elasticity

      E3=20 kPa

      ρ3=1183 kg/m3

      ʋ3=0.499

      Ciliary bodyLinear elasticity

      E4=357.78 MPa

      ρ4=1600 kg/m3

      ʋ4=0.47

      Aqueous humorNewtonian fluid

      ρ5=998 kg/m3

      η=0.00103 Pa·s

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    Jixi Guo, Lihua Fang, Gang Shi, Ruixuan Yu, Yi Zhang, Xinchao Wang, Xuyang Zhang. Finite Element Analysis of Corneal Elasticity After Small Incision Lenticule Extraction Surgery Evaluated by Optical Coherence Elastography[J]. Chinese Journal of Lasers, 2025, 52(3): 0307207

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    Paper Information

    Category: Optical Diagnostics and Therapy

    Received: Sep. 30, 2024

    Accepted: Nov. 22, 2024

    Published Online: Jan. 20, 2025

    The Author Email: Fang Lihua (fanglh71@126.com)

    DOI:10.3788/CJL241231

    CSTR:32183.14.CJL241231

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