To correct the wavefront combining error caused by piston, tilt, and defocus errors, an electrowetting-based liquid lens array is designed. The Comsol and Zemax software packages are employed to simulate the evolution of liquid-liquid interface in the liquid lens, driven by the working voltage. The wavefront correction ability of the liquid lens array for piston, tilt, and curvature errors under different arrangements and element spacings is analyzed. The simulation results indicate that the liquid lens array successfully corrects and compensates for wavefront aberration. The peak-to-valley value of the output wavefront, corrected by the regular hexagonal-shaped arranging liquid lens array, decreased from 45.6864 λ to 0.0340 λ; the root mean square value was reduced from 14.9127 λ to 0.0073 λ, while the Strehl ratio improved from 0.003 to 0.998. The results show that the electrowetting-based liquid lens array has considerable prospects in wavefront correction of adaptive optics field.