Acta Laser Biology Sinica, Volume. 33, Issue 6, 567(2024)

The Inhibition of Wnt/β-catenin Signal Pathway by Luteic Acid Alleviates the Damage and Apoptosis of Periodontal Membrane Cells

WANG Xiaoying*, HAN Zhimei, and LI Chunyan
Author Affiliations
  • Department of Stomatology, Hebei Petro China Central Hospital, Langfang 065000, China
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    References(12)

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    [4] [4] GAO X, DAI J, LI G, et al. Gambogic acid protects LPS-induced apoptosis and inflammation in a cell model of neonatal pneumonia through the regulation of TrkA/Akt signaling pathway[J]. BMC Pharmacology & Toxicology, 2021, 22(1): 28-29.

    [5] [5] DONG Q, JIE Y, MA J, et al. Wnt/-catenin signaling pathway promotes renal ischemia-reperfusion injury through inducing oxidative stress and inflammation response[J]. Journal of Receptors and Signal Transduction Research, 2021, 41(1): 15-18.

    [6] [6] YANG F, HUANG D, XU L, et al. Wnt antagonist secreted frizzled-related protein I (sFRP1) may be involved in the osteogenic differentiation of periodontal ligament cells in chronic apical periodontitis[J]. International Endodontic Journal, 2021, 54(5): 768-779.

    [9] [9] LIU X, NIU Y, XIE W, et al. Tanshinone IIA promotes osteogenic differentiation of human periodontal ligament stem cells via ERK1/2-dependent Runx2 induction[J]. American Journal of Translational Research, 2019, 11(1): 340-350.

    [10] [10] ZHAO X, DING S, LI S, et al. Construction of gambogic acid hpma copolymer coupling rug system and study on anti-tumor activity[J]. Current Drug Delivery, 2022, 19(4): 491-507.

    [13] [13] WU X, LONG L, LIU J, et al. Gambogic acid suppresses inflammation in rheumatoid arthritis rats via PI3K/Akt/mTOR signaling pathway[J]. Molecular Medicine Reports, 2017, 16(5): 7112-7118.

    [16] [16] TANG X, LIU C, LI I, et al. Gambogic acid alleviates inflammation and apoptosis and protects the blood-milk barrier in mastitis induced by LPS[J]. International Immunopharmacology, 2020, 86(4): 106697.

    [18] [18] VALLE A. Arterial stiffness and the canonical Wnt/-catenin pathway[J]. Current Hypertension Reports, 2022, 24(11): 499-507.

    [19] [19] BIAN Y, XIANG J. Salvianolic acid B promotes the osteogenic differentiation of human periodontal ligament cells through Wnt/-catenin signaling pathway[J]. Archives of Oral Biology, 2020, 113: 104693.

    [20] [20] SUKSEN K, JANPIPATKUL K, REABROI S, et al. Gambogic acid inhibits Wnt/-catenin signaling and induces er stress-mediated apoptosis in human cholangiocarcinoma[J]. Asian Pacific Journal of Cancer Prevention, 2021, 22(6): 1913-1920.

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    WANG Xiaoying, HAN Zhimei, LI Chunyan. The Inhibition of Wnt/β-catenin Signal Pathway by Luteic Acid Alleviates the Damage and Apoptosis of Periodontal Membrane Cells[J]. Acta Laser Biology Sinica, 2024, 33(6): 567

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    Paper Information

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    Received: Dec. 13, 2023

    Accepted: Feb. 27, 2025

    Published Online: Feb. 27, 2025

    The Author Email: Xiaoying WANG (wxy2025yes@126.com)

    DOI:10.3969/j.issn.1007-7146.2024.06.011

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