Laser & Optoelectronics Progress, Volume. 55, Issue 12, 121102(2018)

Ultrafast Flow Cytometric Quantitative Phase Imaging System Based on Optical Coherent Detection Technology

Lu Song1 and Yuanhua Feng2、*
Author Affiliations
  • 1 Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, Institute of Photonics Technology, Jinan University, Guangzhou, Guangdong 510632, China
  • 2 College of Information Science and Technology, Jinan University, Guangzhou, Guangdong 510632, China
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    Figures & Tables(7)
    Schematic of the time stretch imaging system
    Structure schematic of optical coherent receiver
    Relationship between resolution limit and dispersion
    Schematic of the time-stretch-based ultrafast polarization cytometric imaging system.(a) Time domain dispersion; (b) spatial dispersion and imaging; (c) optical coherent detection
    (a) Image of resolution target; (b) time domain waveform captured by the detector; (c) differential and Gauss fitting curves
    Phase contrast microscope images and phase images. (a) Phase contrast microscope image of normal nasopharyngeal carcinoma cell slice; (b) phase image of normal nasopharyngeal carcinoma cell slice; (c) phase contrast microscope image of nasopharyngeal carcinoma cell slice treated with growth inhibition drugs; (d) phase image of normal nasopharyngeal carcinoma cell slice treated with growth inhibition drugs
    Phase images (scale bar: 10 μm). (a) Three-dimensional phase image of single nasopharyngeal carcinoma cell; (b) phase images of nasopharyngeal carcinoma cells; (c) phase images of normal nasopharyngeal epithelial cells
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    Lu Song, Yuanhua Feng. Ultrafast Flow Cytometric Quantitative Phase Imaging System Based on Optical Coherent Detection Technology[J]. Laser & Optoelectronics Progress, 2018, 55(12): 121102

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    Paper Information

    Category: Imaging Systems

    Received: May. 11, 2018

    Accepted: Jun. 12, 2018

    Published Online: Aug. 1, 2019

    The Author Email: Yuanhua Feng (favinfeng@163.com)

    DOI:10.3788/LOP55.121102

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