Laser & Optoelectronics Progress, Volume. 59, Issue 6, 0617006(2022)
Diffusion Correlation Spectroscopy for Tissue Blood Flow Monitoring and Its Clinical Applications
Fig. 2. Comparison between tissue blood flow monitoring using fast DCS and traditional DCS[27]. (a) Normalized intensity autocorrelation function; (b) blood flow index
Fig. 4. Calibration method of BFI in skeletal muscle[23]. (a) Experimental protocol; (b) total hemoglobin concentration change; (c) BFI change
Fig. 7. Changes of cerebral blood flow (CBF) and cerebrovascular resistance (CVR) in 11 healthy subjects during cerebral autoregulation evaluation[47]
Fig. 8. Changes of cerebral blood flow, mean arterial pressure, intracranial pressure, and cerebral oxygen tension during impaired cerebral autoregulation and intact cerebral autoregulation[48]
Fig. 9. Cerebral blood flow images before and after mechanical thrombectomy and cerebral blood flow monitoring before, during, and after internal carotid artery recanalization[49]
Fig. 10. Time series diagrams of cerebral blood flow under the change of intrathoracic pressure[50]
Fig. 11. Blood flow changes of gastrocnemius muscle tissue obtained by DCS optical probe[17]. (a)-(c) MRI images of gastrocnemius muscle; (d) diagram of DCS optical probe distance; (e) changes of blood flow in gastrocnemius muscle during cuff compression
Fig. 12. Typical muscle hemodynamic responses during bi-femoral artery bypass graft in a patient with peripheral arterial disease(PAD)[51]. (a) rBF in left calf muscle; (b) rBF in right calf muscle
Fig. 13. Comparison results in a PAD patient before and after 3-month exercise training[52]. (a) Changes of tissue blood flow three months ago; (b) changes of tissue blood flow under treadmill exercise load test after three months; (c) box diagram of tissue blood flow changes in exercise group and control group before and after three months
Fig. 14. Changes of gastrocnemius parameters in exercise group and control group of a PAD patient before and after three months[53]. (a) Metabolic rate of oxygen (rMRO2); (b) relative blood flow (rF); (c) tissue oxygen saturation (rStO2)
Fig. 15. Changes of muscle BFI and StO2 during the cycling exercise[54]. (a) Schematic of riding; (b) muscle BFI and StO2 for a representative subject during the cycling exercise
Fig. 17. Box diagrams of breast tissue blood flow index changes during the neoadjuvant chemotherapy (NAC) treatment[57]. (a) Healthy breast; (b) tumor breast
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Zhe Li, Jinchao Feng, Kebin Jia. Diffusion Correlation Spectroscopy for Tissue Blood Flow Monitoring and Its Clinical Applications[J]. Laser & Optoelectronics Progress, 2022, 59(6): 0617006
Category: Medical Optics and Biotechnology
Received: Dec. 17, 2021
Accepted: Jan. 17, 2022
Published Online: Mar. 8, 2022
The Author Email: Zhe Li (lizhe1023@bjut.edu.cn), Jinchao Feng (fengjc@bjut.edu.cn), Kebin Jia (kebinj@bjut.edu.cn)