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Laser & Optoelectronics Progress, Volume. 60, Issue 4, 0417002(2023)

Optical Coherence Tomography-Based Identification for Papillary Carcinoma of Thyroid

Zengming Li1,1、">, Chao Zhao1,1、">, Xu Zhang1,1、">, Weizheng Mao2、**, Hang Zhao1,1、">, Xiaofeng Shi1,1、">, and Jun Ma1、*
Author Affiliations
  • 1Optics and Optoelectronics Laboratory, Faculty of Information Science and Engineering, Ocean University of China, Qingdao 266100, Shandong, China
  • 2Department of General Surgery, Qingdao Municipal Hospital, Qingdao 266071, Shandong, China
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    Figures&Tables (6)
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    References (18)
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    Figures & Tables(6)
    Flowchart of OCT images identification

    Fig. 1. Flowchart of OCT images identification

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    Typical OCT images and histological images of normal tissues and cancerous thyroid tissues. (a) (c) Enface OCT image of normal tissues; (b) histopathological image of normal tissues; (d) (f) enface OCT image of papillary carcinoma tissues of thyroid; (e) histopathological image of papillary carcinoma tissues of thyroid

    Fig. 2. Typical OCT images and histological images of normal tissues and cancerous thyroid tissues. (a) (c) Enface OCT image of normal tissues; (b) histopathological image of normal tissues; (d) (f) enface OCT image of papillary carcinoma tissues of thyroid; (e) histopathological image of papillary carcinoma tissues of thyroid

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    Scatter diagrams of principal components of the GLCM-GH-CSAC combination. (a) 2D scatter diagram of PC1 versus PC2; (b) 2D scatter diagram of PC1 versus PC3; (c) 2D scatter diagram of PC2 versus PC3; (d) 3D scatter diagram of PC1, PC2, and PC3

    Fig. 3. Scatter diagrams of principal components of the GLCM-GH-CSAC combination. (a) 2D scatter diagram of PC1 versus PC2; (b) 2D scatter diagram of PC1 versus PC3; (c) 2D scatter diagram of PC2 versus PC3; (d) 3D scatter diagram of PC1, PC2, and PC3

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    Scatter diagrams of principal components of the GLCM-GH-LM combination. (a) 2D scatter diagram of PC1 versus PC2; (b) 2D scatter diagram of PC1 versus PC3; (c) 2D scatter diagram of PC2 versus PC3; (d) 3D scatter diagram of PC1, PC2, and PC3

    Fig. 4. Scatter diagrams of principal components of the GLCM-GH-LM combination. (a) 2D scatter diagram of PC1 versus PC2; (b) 2D scatter diagram of PC1 versus PC3; (c) 2D scatter diagram of PC2 versus PC3; (d) 3D scatter diagram of PC1, PC2, and PC3

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    Optimization results of the grid search of SVM. (a) GLCM-GH-CSAC-LM; (b) GLCM-CSAC-LM; (c) GH-CSAC-LM; (d) GLCM-GH-LM

    Fig. 5. Optimization results of the grid search of SVM. (a) GLCM-GH-CSAC-LM; (b) GLCM-CSAC-LM; (c) GH-CSAC-LM; (d) GLCM-GH-LM

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    • Table 1. Identification results of different texture feature combinations based on SVM for papillary carcinoma of thyroid

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      Table 1. Identification results of different texture feature combinations based on SVM for papillary carcinoma of thyroid

      AlgorithmSensitivity /%Specificity /%Accuracy /%
      GLCM85.790.387.1
      GH82.280.681.5
      CSAC85.990.288.1
      LM89.884.187.1
      GLCM-GH-CSAC87.389.888.6
      GLCM-GH-LM96.392.294.3
      GLCM-CSAC-LM89.691.691.0
      GH-CSAC-LM91.493.692.4
      GLCM-GH-CSAC-LM88.690.689.5
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    Zengming Li, Chao Zhao, Xu Zhang, Weizheng Mao, Hang Zhao, Xiaofeng Shi, Jun Ma. Optical Coherence Tomography-Based Identification for Papillary Carcinoma of Thyroid[J]. Laser & Optoelectronics Progress, 2023, 60(4): 0417002

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    Paper Information

    Category: Medical Optics and Biotechnology

    Received: Feb. 23, 2022

    Accepted: Mar. 14, 2022

    Published Online: Feb. 14, 2023

    The Author Email: Weizheng Mao (Greenwood8838@163.com), Jun Ma (majun@ouc.edu.cn)

    DOI:10.3788/LOP220802

    Topics

    laser devices and laser physics
    Lasers and Laser Optics
    Laser physics
    laser manufacturing
    Instrumentation, Measurement and Metrology