Background-free detection of molecular chirality using a single-color beam [Invited]

[1] J. Gal. The discovery of stereoselectivity at biological receptors: Arnaldo Piutti and the taste of the asparagine enantiomers-history and analysis on the 125th anniversary. Chirality, 24, 959(2012).

[2] P. Fischer, F. Hache. Nonlinear optical spectroscopy of chiral molecules. Chirality, 17, 421(2005).

[3] A. J. Hutt, S. C. Tan. Drug chirality and its clinical significance. Drugs, 52, 1(1996).

[4] D. J. Abraham, J. Singh, T. J. Hagen. Chirality and biological activity. Burger’s Medicinal Chemistry and Drug Discovery, 127(2010).

[5] S. Giri, A. M. Dudzinski, J. C. Tremblay, G. Dixit. Time-dependent electronic current densities in chiral molecules. Phys. Rev. A, 102, 063103(2020).

[6] N. Berova, P. L. Polavarapu, K. Nakanishi, R. W. Woody. Comprehensive Chiroptical Spectroscopy: Applications in Stereochemical Analysis of Synthetic Compounds, Natural Products, and Biomolecules(2012).

[7] E. Castiglioni, S. Abbate, F. Lebon, G. Longhi. Chiroptical spectroscopic techniques based on fluorescence. Methods Appl. Fluoresc., 2, 024006(2014).

[8] V. Parchaňskýř, J. Kapitán, P. Bouř. Inspecting chiral molecules by Raman optical activity spectroscopy. RSC Adv., 4, 57125(2014).

[9] M. Pitzer, M. Kunitski, A. S. Johnson, T. Jahnke, H. Sann, F. Sturm, L. PH. H. Schmidt, H. Schmidt-Böcking, R. Dörner, J. Stohner, J. Kiedrowski, M. Reggelin, S. Marquardt, A. Schießer, R. Berger, M. S. Schöffler. Direct determination of absolute molecular stereochemistry in gas phase by Coulomb explosion imaging. Science, 341, 1096(2013).

[10] P. Herwig, K. Zawatzky, M. Grieser, O. Heber, B. Jordon-Thaden, C. Krantz, O. Novotný, R. Repnow, V. Schurig, D. Schwalm, Z. Vager, A. Wolf, O. Trapp, H. Kreckel. Imaging the absolute configuration of a chiral epoxide in the gas phase. Science, 342, 1084(2013).

[11] D. Patterson, M. Schnell, J. Doyle. Enantiomer-specific detection of chiral molecules via microwave spectroscopy. Nature, 497, 475(2013).

[12] S. Eibenberger, J. Doyle, D. Patterson. Enantiomer-specific state transfer of chiral molecules. Phys. Rev. Lett., 118, 123002(2017).

[13] N. Böwering, T. Lischke, B. Schmidtke, N. Müller, T. Khalil, U. Heinzmann. Asymmetry in photoelectron emission from chiral molecules induced by circularly polarized light. Phys. Rev. Lett., 86, 1187(2001).

[14] A. Comby, S. Beaulieu, M. Boggio-Pasqua, D. Descamps, F. Légaré, L. Nahon, S. Petit, B. Pons, B. Fabre, Y. Mairesse, V. Blanchet. Relaxation dynamics in photoexcited chiral molecules studied by time-resolved photoelectron circular dichroism: toward chiral femtochemistry. J. Phys. Chem. Lett., 7, 4514(2016).

[15] S. Beaulieu, A. Comby, A. Clergerie, J. Caillat, D. Descamps, N. Dudovich, B. Fabre, R. Géneaux, F. Légaré, S. Petit, B. Pons, G. Porat, T. Ruchon, R. Taïeb, V. Blanchet, Y. Mairesse. Attosecond-resolved photoionization of chiral molecules. Science, 358, 1288(2017).

[16] P. B. Corkum. Plasma perspective on strong field multiphoton ionization. Phys. Rev. Lett., 71, 1994(1993).

[17] A. D. Shiner, B. E. Schmidt, C. Trallero-Herrero, H. J. Wörner, S. Patchkovskii, P. B. Corkum, J.-C. Kieffer, F. Légaré, D. M. Villeneuve. Probing collective multi-electron dynamics in xenon with high-harmonic spectroscopy. Nat. Phys., 7, 464(2011).

[18] S. Ghimire, A. DiChiara, E. Sistrunk, P. Agostini, L. F. DiMauro, D. A. Reis. Observation of high-order harmonic generation in a bulk crystal. Nat. Phys., 7, 138(2011).

[19] W. Xiong, J. Geng, J. Tang, L. Peng, Q. Gong. Mechanisms of below-threshold harmonic generation in atoms. Phys. Rev. Lett., 112, 233001(2014).

[20] L. Li, P. Lan, X. Zhu, T. Huang, Q. Zhang, M. Lein, P. Lu. Reciprocal-space-trajectory perspective on high-harmonic generation in solids. Phys. Rev. Lett., 122, 193901(2019).

[21] L. Li, P. Lan, X. Zhu, P. Lu. Huygens-Fresnel picture for high harmonic generation in solids. Phys. Rev. Lett., 127, 223201(2021).

[22] S. Baker, J. S. Robinson, C. A. Haworth, H. Teng, R. A. Smith, C. C. Chirila, M. Lein, J. W. G. Tisch, J. P. Marangos. Probing proton dynamics in molecules on an attosecond time scale. Science, 312, 424(2006).

[23] O. Smirnova, Y. Mairesse, S. Patchkovskii, N. Dudovich, D. Villeneuve, P. Corkum, MY. Ivanov. High harmonic interferometry of multi-electron dynamics in molecules. Nature, 460, 972(2009).

[24] L. He, P. Lan, A. Le, B. Wang, B. Wang, X. Zhu, P. Lu, C. D. Lin. Real-time observation of molecular spinning with angular high-harmonic spectroscopy. Phys. Rev. Lett., 121, 163201(2018).

[25] L. He, Q. Zhang, P. Lan, W. Cao, X. Zhu, C. Zhai, F. Wang, W. Shi, M. Li, X. Bian, P. Lu, A. D. Bandrauk. Monitoring ultrafast vibrational dynamics of isotopic molecules with frequency modulation of high-order harmonics. Nat. Commun., 9, 1108(2018).

[26] L. Li, T. Huang, P. Lan, J. Li, Y. Zhang, X. Zhu, L. He, W. Cao, P. Lu. Fingerprint of the interbond electron hopping in second-order harmonic generation. Phys. Rev. Lett., 128, 027401(2022).

[27] R. Cireasa, A. E. Boguslavskiy, B. Pons, M. C. H. Wong, D. Descamps, S. Petit, H. Ruf, N. Thiré, A. Ferré, J. Suarez, J. Higuet, B. E. Schmidt, A. F. Alharbi, F. Légaré, V. Blanchet, B. Fabre, S. Patchkovskii, O. Smirnova, Y. Mairesse, V. R. Bhardwaj. Probing molecular chirality on a sub-femtosecond timescale. Nat. Phys., 11, 654(2015).

[28] O. Smirnova, Y. Mairesse, S. Patchkovskii. Opportunities for chiral discrimination using high harmonic generation in tailored laser fields. J. Phys. B, 48, 234005(2015).

[29] Y. Harada, E. Haraguchi, K. Kaneshima, T. Sekikawa. Circular dichroism in high-order harmonic generation from chiral molecules. Phys. Rev. A, 98, 021401(2018).

[30] D. Baykusheva, H. J. Wörner. Chiral discrimination through bielliptical high-harmonic spectroscopy. Phys. Rev. X, 8, 031060(2018).

[31] O. Neufeld, D. Ayuso, P. Decleva, M. Y. Ivanov, O. Smirnova, O. Cohen. Ultrasensitive chiral spectroscopy by dynamical symmetry breaking in high harmonic generation. Phys. Rev. X, 9, 031002(2019).

[32] D. Ayuso, O. Neufeld, A. F. Ordonez, P. Decleva, G. Lerner, O. Cohen, M. Ivanov, O. Smirnova. Synthetic chiral light for efficient control of chiral light–matter interaction. Nat. Photonics, 13, 866(2019).

[33] D. Ayuso, A. F. Ordonez, P. Decleva, M. Ivanov, O. Smirnova. Enantio-sensitive unidirectional light bending. Nat. Commun., 12, 3951(2021).

[34] D. Ayuso, A. F. Ordonez, P. Decleva, M. Ivanov, O. Smirnova. Strong chiral response in non-collinear high harmonic generation driven by purely electric-dipole interactions. Opt. Express, 30, 4659(2022).

[35] O. Neufeld, O. Wengrowicz, O. Peleg, A. Rubio, O. Cohen. Detecting multiple chiral centers in chiral molecules with high harmonic generation. Opt. Express, 30, 3729(2022).

[36] O. Neufeld, D. Podolsky, O. Cohen. Floquet group theory and its application to selection rules in harmonic generation. Nat. Commun., 10, 405(2019).

[37] X. Zhu, X. Liu, P. Lan, D. Wang, Q. Zhang, W. Li, P. Lu. Anomalous circular dichroism in high harmonic generation of stereoisomers with two chiral centers. Opt. Express, 24, 24824(2016).

[38] D. Wang, X. Zhu, X. Liu, L. Li, X. Zhang, P. Lan, P. Lu. High harmonic generation from axial chiral molecules. Opt. Express, 25, 23502(2017).

[39] M. A. L. Marques, A. Castro, G. F. Bertsch, A. Rubio. Octopus: a first-principles tool for excited electron-ion dynamics. Comput. Phys. Commun., 151, 60(2003).

[40] A. Castro, H. Appel, M. Oliveira, C. A. Rozzi, X. Andrade, F. Lorenzen, M. A. L. Marques, E. K. U. Gross, A. Rubio. Octopus: a tool for the application of time-dependent density functional theory. Phys. Stat. Sol., 243, 2465(2006).

[41] X. Andrade, D. Strubbe, U. De Giovannini, A. H. Larsen, M. J. T. Oliveira, J. Alberdi-Rodriguez, A. Varas, I. Theophilou, N. Helbig, M. J. Verstraete, L. Stella, F. Nogueira, A. Aspuru-Guzik, A. Castro, M. A. L. Marques, A. Rubio. Real-space grids and the Octopus code as tools for the development of new simulation approaches for electronic systems. Phys. Chem. Chem. Phys., 17, 31371(2015).

[42] J. P. Perdew, A. Zunger. Self-interaction correction to density-functional approximations for many-electron systems. Phys. Rev. B, 23, 5048(1981).

[43] C. Hartwigsen, S. Goedecker, J. Hutter. Relativistic separable dual-space Gaussian pseudopotentials from H to Rn. Phys. Rev. B, 58, 3641(1998).

[44] O. E. Alon, V. Averbukh, N. Moiseyev. Selection rules for the high harmonic generation spectra. Phys. Rev. Lett., 80, 3743(1998).

[45] X. Liu, X. Zhu, L. Li, Y. Li, Q. Zhang, P. Lan, P. Lu. Selection rules of high-order-harmonic generation: symmetries of molecules and laser fields. Phys. Rev. A, 94, 033410(2016).

[46] X. Zhu, P. Lu, M. Lein. Control of the geometric phase and nonequivalence between geometric-phase definitions in the adiabatic limit. Phys. Rev. Lett., 128, 030401(2022).

[47] R. D. Johnson. NIST computational chemistry comparison and benchmark database.

[48] [48] Left-handed CHFClBr:C(0,0,0); H(0.0592,1.0771,0.1417); Cl(1.2383,−0.4784,−1.1326); F(0.2048,−0.6098,1.1937); Br(−1.7683,−0.4376,−0.6315). Here, angstroms are used.

[49] R. Géneaux, A. Camper, T. Auguste, O. Gobert, J. Caillat, R. Taïeb, T. Ruchon. Synthesis and characterization of attosecond light vortices in the extreme ultraviolet. Nat. Commun., 7, 12583(2016).

Cited By

[1] Wanchen Tao, Siqi Sun, Lixin He, Yanqing He, Jianchang Hu, Yu Deng, Chengqing Xu, Pengfei Lan, Peixiang Lu.

Tools

Get Citation

Copy Citation Text

Yuhang Chen, Xiaosong Zhu, Pengfei Lan, Peixiang Lu, "Background-free detection of molecular chirality using a single-color beam [Invited]," Chin. Opt. Lett. 20, 100004 (2022)

Download Citation

EndNote(RIS)BibTex Plain Text

Set citation alerts for article

Save article for my favorites

Paper Information

Special Issue: ULTRAFAST OPTICS: FUNDAMENTALS AND APPLICATIONS

Received: Apr. 29, 2022

Accepted: Jul. 14, 2022

Published Online: Sep. 13, 2022

The Author Email: Xiaosong Zhu (zhuxiaosong@hust.edu.cn), Pengfei Lan (pengfeilan@hust.edu.cn)

DOI:10.3788/COL202220.100004

Topics

laser devices and laser physics

Lasers and Laser Optics

Laser physics

laser manufacturing

Instrumentation, Measurement and Metrology