Chinese Journal of Lasers, Volume. 38, Issue 2, 204003(2011)
Artesunate Induces Reactive Oxygen Species-Mediated Apoptosis
[1] [1] R. K. Haynes. Artemisinin and derivatives: the future for malaria treatment [J]. Curr. Opin. Infect. Dis., 2001, 14(6): 719~726
[2] [2] N. J. White. Antimalarial drug resistance[J]. J. Clin. Invest., 2004, 113(8): 1084~1092
[3] [3] N. J. White, P. L. Olliaro. Strategies for the prevention of antimalarial drug resistance: rationale for combination chemotherapy for malaria[J]. Parasitol. Today, 1996, 12(10): 399~401
[4] [4] T. Efferth, H. Dunstan, A. Sauerbrey et al.. The anti-malarial artesunate is also active against cancer[J]. Int. J. Oncol., 2001, 18(4): 767~773
[5] [5] N. P. Singh, H. Lai. Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells [J]. Life Sci., 2001, 70(1): 49~56
[6] [6] R. Dell′Eva, U. Pfeffer, R. Vene et al.. Inhibition of angiogenesis in vivo and growth of Kaposi′s sarcoma xenograft tumors by the anti-malarial artesunate [J]. Biochem. Pharmacol., 2004, 68(12): 2359~2366
[7] [7] H. J. Zhou, W. Q. Wang, G. D. Wu et al.. Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells[J]. Vasc. Pharmacol., 2007, 47(2-3): 131~138
[8] [8] H. H. Chen, L. L. You, S. B. Li. Artesunate reduces chicken chorioallantoic membrane neovascularisation and exhibits antiangiogenic and apoptotic activity on human microvascular dermal endothelial cell[J]. Cancer Lett., 2004, 211(2): 163~173
[9] [9] J. H. Du, H. D. Zhang, Z. J. Ma et al.. Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo[J]. Cancer Chemother. Pharmacol., 2009, 65(5): 895~902
[10] [10] T. Efferth, A. Benakis, M. R. Romero et al.. Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron[J]. Free Radic. Biol. Med., 2004, 37(7): 998~1009
[11] [11] K. M. Anderson, T. Seed, D. Ou et al.. Free radicals and reactive oxygen species in programmed cell death[J]. Med. Hypotheses, 1999, 52(5): 451~463
[12] [12] D. R. Green, G. Kroemer. The pathophysiology of mitochondrial cell death[J]. Science, 2004, 305(5684): 626~629
[13] [13] J. C. Martinou, D. R. Green. Breaking the mitochondrial barrier[J]. Nat. Rev. Mol. Cell Biol., 2001, 2(1): 63~67
[15] [15] A. A. Marghoob, C. A. Charles, K. J. Busam et al.. In vivo confocal scanning laser microscopy of a series of congenital melanocytic nevi suggestive of having developed malignant melanoma[J]. Arch Dermatol., 2005, 141(11): 1401~1412
[21] [21] Dmitry B. Zorov, Evgeny Kobrinsky, Magdalena Juhaszova et al.. Examining intracellular organelle function using fluorescent probes from animalcules to quantum dots[J]. Circulation Research, 2004, 95(3): 239~252
[22] [22] Rachel Jones, Meredith B. Baker, Martina Weber et al.. Molecular beacons can assess changes in expression and 3′-polyadenylation of human eNOS mRNA[J]. Am. J. Physiol. Cell Physiol., 2009, 296(3): C498~C504
[23] [23] James M. Antonini, Tina G. Charron, Jenny R. Roberts et al.. Application of laser scanning confocal microscopy in the analysis of particle-induced pulmonary fibrosis[J]. Toxicological Sciences, 1999, 51(1): 126~134
[24] [24] Stacey A. Maskarinec, Christian Franck, David A. Tirrell et al.. Quantifying cellular traction forces in three dimensions[J]. PNAS, 2009, 106(52): 22108~22113
[25] [25] P. Jezek, L. Hlavata. Mitochondria in homeostasis of reactive oxygen species in cell, tissues and organism[J]. Int. J. Biochem. Cell Biol., 2005, 37(12): 2478~2503
[26] [26] J. Nitobe, S. Yamaguchi, M. Okuyama et al.. Reactive oxygen species regulate FLICE inhibitory protein (FLIP) and susceptibility to fas-mediated apoptosis in cardiac myocytes[J]. Cardiovasc. Res., 2003, 57(1): 119~128
[27] [27] K. Izeradjene, L. Douglas, D. M. Tillman et al.. Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines[J]. Cancer Res., 2005, 65(16): 7436~7445
Get Citation
Copy Citation Text
Zhou Chenjuan, Pan Wenliang, Chen Tongsheng. Artesunate Induces Reactive Oxygen Species-Mediated Apoptosis[J]. Chinese Journal of Lasers, 2011, 38(2): 204003
Category: biomedical photonics and laser medicine
Received: Jul. 5, 2010
Accepted: --
Published Online: Jan. 30, 2011
The Author Email: Chenjuan Zhou (zhouchenyu1987@126.com)