The adhesion coefficient between the wheel and rail has a significance influence on the safety and stability of the train operation. In winter a thin film of ice presemed onrail will greatly reduce the wheel-rail adhesion coefficient. In this paper the contact region of wheel/rail will be divided into two regions, that is the solid contact region of ice-steel and the mixed lubrication contact region of water-steel according to the phase diagram of ice and the principle of pressure melt. The adhesion coefficient of high-speed wheel/rail is investigated with the variation of speed from 100 km/h to 500 km/h under the temperature region from -21 ℃ to 0 ℃ based on the unified Reynolds equation. Regular patterns on wheel surface, such as longitudinal, transverse and rhombus, formed by laser texturing, will improve the adhesion coefficient of wheel/rail under ice-water mixed lubrication. The investigation is helpful for adhesion controlling technology of high-speed railway.