Research and Design of Laser Drive System Based on Flow Cytometry

Zihan ZHANG; Zhencheng CHEN; Wang CHEN; Xuehui TANG; Tianji LEI; Chu TAN; Fuyin ZHU; Aiwen LIAO; Changlin XIAO; Shimin YIN; Cheng FANG

doi:10.3788/gzxb20245306.0614003

Acta Photonica Sinica, Volume. 53, Issue 6, 0614003(2024)

Research and Design of Laser Drive System Based on Flow Cytometry

Zihan ZHANG¹, Zhencheng CHEN², Wang CHEN³, Xuehui TANG³, Tianji LEI², Chu TAN³, Fuyin ZHU³, Aiwen LIAO³, Changlin XIAO³, Shimin YIN^2,4、**, and Cheng FANG^2、*

Author Affiliations

¹School of Electronic Engineering and Automation， Guilin University of Electronic Technology， Guilin 541004， China

²School of Life & Environmental Sciences， Guilin University of Electronic Technology， Guilin 541004， China

³URIT Medical Electronic Co.，Ltd.， Guilin 541004， China

⁴Guangxi Key Laboratory of Automatic Detection Technology and Instrument， Guilin University of Electronic Technology， Guilin 541004， China

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Figures & Tables(13)

Fig. 1. Principle of flow cytometry

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Fig. 2. Structure of LD drive system

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Fig. 3. Constant optical power drive circuit structure

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Fig. 4. Constant optical power drive circuit

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Fig. 5. Light intensity detection amplifier circuit

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Fig. 6. Constant temperature control circuit

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Fig. 7. Variation of laser operating temperature

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Fig. 8. Variation of laser outputs optical power

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Fig. 9. Variation of laser AC RMS

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Fig. 10. Variation of laser outputs the central wavelength

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Fig. 11. Test results of quality control by flow cytometry

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Table 1. The results of laser noise for short-term and long-term
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Table 1. The results of laser noise for short-term and long-term
Sample DC RMS/mV AC RMS/μV Laser noise/%
Short-term 848.2 972.1 0.114
Long-term 831.8 906.4 0.109

Table 2. The results of CV values for quality control tests at different ambient temperatures
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Table 2. The results of CV values for quality control tests at different ambient temperatures
Sample FSC CV/% FITC CV/% PE CV/%
Temperature control 1.03 1.70 1.02
Room temperature 1.45 2.14 1.18

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Zihan ZHANG, Zhencheng CHEN, Wang CHEN, Xuehui TANG, Tianji LEI, Chu TAN, Fuyin ZHU, Aiwen LIAO, Changlin XIAO, Shimin YIN, Cheng FANG. Research and Design of Laser Drive System Based on Flow Cytometry[J]. Acta Photonica Sinica, 2024, 53(6): 0614003

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