Biotic Resources, Volume. 47, Issue 3, 242(2025)
Research progress on health claims of Chaenomeles speciosa
[1] Xiu Y F, Cao Y H, Wang P. Optimization of processing technics of Fructus Chaenomelis softened by methods of moistening and steaming by evaluation synthetically with several markers. Lishizhen Medicine and Materia Medica Research, 20, 1247-1249(2009).
[2] Zhao X H, Wang M H, Meng X X et al. Discussion on the non-pollution cultivation technology of Chaenomelis Fructus. Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology, 20, 2075-2081(2018).
[3] Huang J Y, Wang Y L, Li T et al. Research progress on chemical composition, pharmacological action and processing and utilization of papaya. South-Central Agricultural Science and Technology, 241-245, 253(2023).
[4] Liu Y. Study on quality evaluation and fingerprint of papaya(2009).
[5] Yan H G, Chen J H. Botanical characteristics and economical status of Chaenomeles speciosa. Journal of Kaili University, 30, 43-44(2012).
[6] Zhang Q, Wang G, He Z X et al. Varieties classification of the Chinese quince fruit and the strategy for management. Journal of Plant Genetic Resources, 6, 339-343(2005).
[7] Guo K Y, Zhang M D, Wu Y Z et al. Comparative study on the characters and composition indexes of Chaenomeles speciosa fruits in different producing areas. Journal of Chinese Medicinal Materials, 43, 2396-2400(2020).
[8] Deng C F, Luo C, Ren X Y et al. Comparison of the contents of ursolic acid and oleanolic acid in Chaenomeles with different harvest periods. Asia-Pacific Traditional Medicine, 12, 30-31(2016).
[9] Li Y Z, Jiang H B. Study advance in chemical constituents from plants of Chaenomeles speciosa and their bioactivities. Technology & Development of Chemical Industry, 47, 35-38(2018).
[10] Yu S, Zhang L, Shan M Q et al. Simultaneous determination of eight organic acids in Chaenomelis Fructus by UFLC-MS. Chinese Traditional and Herbal Drugs, 47, 2465-2469(2016).
[11] Yang Y B, Yang Y, Li X et al. Studies on the chemical constituents of Chaenomeles speciosa. Journal of Chinese Medicinal Materials, 32, 1388-1390(2009).
[12] Hu Y, Hu Y L. Clinical effect of Wumei Mugua decoction on functional constipation in children. Inner Mongolia Journal of Traditional Chinese Medicine, 41, 13-14(2022).
[13] Wang B. Clinical observation on the treatment of rheumatoid arthritis (cold-dampness stagnation syndrome) with Jiawei Jiming Powder(2019).
[14] Tao S Y, Zhang L X, Liu G. Brief analysis of dietary therapy characteristics of melons and fruits in Wang Mengying’s Sui Xi Ju Yin Shi Pu. Global Traditional Chinese Medicine, 13, 1217-1220.
[15] Yi F. Papaya for both medicine and food. Food and Health, 19, 30(2007).
[16] Liu Y, Zhao Y L, Cao Q et al. Research progress on health claims of Poria cocos. Biotic Resources, 47, 9-20(2025).
[17] Ge Y B, Peng H S. Chinese Medicinal Chaenomeles(2024).
[18] Zhou W J, Yang T K, Wang Y T et al. Effects of glucosides of Chaenomeles speciosa on anti-inflammatory intervention and cytokine expression in AA rats. Medical Innovation of China, 19, 34-39(2022).
[19] Gu Z W, Feng S, Jiang H Q et al. Effect of Chaenomelis Fructus alcohol extract on arthritis inflammation and apoptosis of synovial cells in rheumatoid arthritis model. Chinese Journal of Experimental Traditional Medical Formulae, 26, 45-50(2020).
[20] Duan Z H, Jin C, Deng Y et al. Exploring the chondroprotective effect of Chaenomeles speciosa on glucose-6-phosphate isomerase model mice using an integrated approach of network pharmacology and experimental validation. Journal of Ethnopharmacology, 314, 116553(2023).
[21] Li X, Yang Y B, Yang Q et al. Anti-inflammatory and analgesic activities of Chaenomeles speciosa fractions in laboratory animals. Journal of Medicinal Food, 12, 1016-1022(2009).
[22] Shi M Q, Qin H L, Zhang Y F et al. Effect of total triterpene from Chaenomeles speciosa(Sweet) Nakaion on cytokines in LPS-stimulated RAW264.7 cells. Pharmacology and Clinics of Chinese Materia Medica, 32, 76-80(2016).
[23] Luo Y. Experimental study on Chaenomeles extract regulating hepatocyte miR-294a-3p/Mfn2 signaling pathway to improve non-alcoholic steatohepatitis(2022).
[24] Li X X, Wei C L, Liu C Q et al. Chaenomeles speciosa fermentation improves nonalcoholic steatohepatitis in mice via miR-350-3p/TLR4 pathway. Traditional Chinese Drug Research and Clinical Pharmacology, 33, 419-425(2022).
[25] Liu S. Isolation of oleanolic acid and preparation of nanoparticles with protective effects against CCl4-induced liver injury in mice(2020).
[26] Qin H L, Zhang Y F, Wang X Y et al. Effect of ethyl acetate extract from Chaenomeles speciosa(Sweet) Nakaion on the expression of miR-423-5p, TFF1 and p53 in acute gastric ulcer mice. Pharmacology and Clinics of Chinese Materia Medica, 32, 80-82(2016).
[27] Guo C, Huang K K, Zeng J H et al. Extract of Chaenomeles speciosa (Sweet) nakai prevents intestinal mucosal injury induced by non-steroidal anti-inflammatory drugs (NSAIDs) in mice. Modern Food Science and Technology, 35, 45-51(2019).
[28] Zhang Y Y, Xu H Y, He H B et al. Total triterpenes from the fruits of Chaenomeles speciosa (Sweet) Nakai protects against indomethacin-induced gastric mucosal injury: involvement of TFF1-mediated EGF/EGFR and apoptotic pathways. Journal of Pharmacy and Pharmacology, 72, 409-423(2020).
[29] Ye W Y, Wang J Z, Ye H et al. Study of fruit pulp fabrication process of Chaenomeles speciosa and its effect of hypolipidemic. Journal of China Three Gorges University (Natural Sciences), 37, 110-112(2015).
[30] Wang Z, Li P, Wang C et al. Protective effects of Arctium lappa L. root extracts (AREs) on high fat diet induced quail atherosclerosis. BMC Complement Altern Med, 1-11(2015).
[31] Tian B M, Xie X M, Shen P P et al. Comparison of the antioxidant activities and the chemical compositions of the antioxidants of different polarity crude extracts from the fruits of Chaenomeles speciosa (Sweet) Nakai. Journal of Planar Chromatography-Modern TLC, 28, 443-447(2015).
[32] Chen K, You J, Tang Y et al. Supplementation of superfine powder prepared from Chaenomeles speciosa fruit increases endurance capacity in rats via antioxidant and Nrf2/ARE signaling pathway. Evidence-Based Complementary and Alternative Medicine, 2014, 976438(2014).
[33] Du H, Wu J, Li H et al. Polyphenols and triterpenes from Chaenomeles fruits: chemical analysis and antioxidant activities assessment. Food Chemistry, 141, 4260-4268(2013).
[34] Zhang L, Cheng Y X, Liu A L et al. Antioxidant, anti-inflammatory and anti-influenza properties of components from Chaenomeles speciosa. Molecules, 15, 8507-8517(2010).
[35] Wang X D, Dong M, Li N et al. Study on the antimicrobial activity of Chaenomeles speciosa S.Nakai. Science and Technology of Food Industry, 32, 175-179(2011).
[36] Wang Z J, Jiang Q, Li P P et al. The water extract of Ampelopsis grossedentata alleviates oxidative stress and intestinal inflammation. Antioxidants, 12, 547(2023).
[37] Qu X Q. Extraction and separation of triterpenoid acids from Chaenomeles speciosa and their antibacterial properties in vitro(2011).
[38] Zhang J W, Ma H, Wei Y et al. The anti-DHBV activity of lamivudine combined with protocatechuic acid in vivo. Journal of Hubei University (Natural Science), 37, 310-315(2015).
[39] Munafò F, Donati E, Brindani N et al. Quercetin and luteolin are single-digit micromolar inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase. Scientific Reports, 12, 10571(2022).
[40] Gao H Y. Studies on chemical constituents and anti-cancer and hair-promoting activities of Radix Astragali and Fructus Chaenomelis(2002).
[41] Feng M L, Xu H Y, He H B et al. Total triterpenes from Chaenomeles induce apoptosis in gastric cancer cells by regulating miR-10a and PI3K/Akt/mTOR/p70S6K signaling pathway. Journal of Chinese Medicinal Materials, 42, 2929-2935(2019).
[42] Wang M Q, Cai S B, Ji B P. Antioxidant activity and growth inhibition for HepG2 cells of Chinese quince seed. Food Science and Technology, 38, 207-210, 217(2013).
[43] Deng Y J, Huang L X, Zhang C H et al. Novel polysaccharide from Chaenomeles speciosa seeds: structural characterization, α-amylase and α-glucosidase inhibitory activity evaluation. International Journal of Biological Macromolecules, 153, 755-766(2020).
[44] Zhao G, Jiang Z H, Zheng X W et al. Dopamine transporter inhibitory and antiparkinsonian effect of common flowering quince extract. Pharmacology Biochemistry and Behavior, 90, 363-371(2008).
[45] Zhang G B, Su Y Q, Deng C Z. Experimental study on long-term toxicity of Mugua pills to rats. Hubei Journal of Traditional Chinese Medicine, 28, 51-53(2006).
[46] Lu J T, Xu D X, Sun M F et al. Study on teratogenicity of glycosides of Chaenomelesspeciosa. Carcinogenesis, 20, 27-29(2008).
[47] Lu J T, Wei W. Study on genetic toxicity of glycosides of Chaenomelesspeciosa. Acta Universitatis Medicinalis Anhui, 48, 922-925(2013).
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Yuebin Ge, Zhangyaoyu Yuan, Mingzhen Zhang, Songtong Wan, Hang Sun, Li Xiang, Shenghu Chen. Research progress on health claims of Chaenomeles speciosa[J]. Biotic Resources, 2025, 47(3): 242
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Received: Dec. 16, 2024
Accepted: Jun. 9, 2025
Published Online: Jul. 28, 2025
The Author Email: Shenghu Chen (283547652@qq.com)