Laboratory Animal and Comparative Medicine, Volume. 45, Issue 3, 279(2025)
Optimization of Surgical Procedure and Efficacy Evaluation of Aortic Calcification Model in Rats with Chronic Kidney Disease
[1] [1] HUANG A R, GUO G Y, YU Y Q, et al. The roles of collagen in chronic kidney disease and vascular calcification[J]. J Mol Med, 2021, 99(1): 75-92. DOI: 10.1007/s00109-020-02014-6.
[3] [3] YE Y Z, CHEN A, LI L, et al. Repression of the antiporter SLC7A11/glutathione/glutathione peroxidase 4 axis drives ferroptosis of vascular smooth muscle cells to facilitate vascular calcification[J]. Kidney Int. 2022 102(6): 1259-1275. DOI: 10.1016/j.kint.2022.07.034.
[7] [7] SHOBEIRI N, ADAMS M A, HOLDEN R M. Vascular calcification in animal models of CKD: a review[J]. Am J Nephrol, 2010, 31(6): 471-481. DOI: 10.1159/000299794.
[8] [8] LIU Y J, GUO Y, BAO S M, et al. Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5[J]. Cell Death Dis, 2022, 13(3): 278. DOI: 10.1038/s41419-022-04703-1.
[10] [10] WU X J, SHEN S J, WU J Y, et al. ENPP1 ameliorates vascular calcification via inhibiting the osteogenic transformation of VSMCs and generating PPi[J]. Open Med, 2023, 18(1): 20230861. DOI: 10.1515/med-2023-0861.
[11] [11] CHEN C Z, LI Y D, LU H L, et al. Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis[J]. Exp Biol Med, 2022, 247(16): 1420-1432. DOI: 10.1177/15353702221095456.
[12] [12] LIU X Y, CHEN A, LIANG Q C, et al. Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway[J]. Aging Cell, 2021, 20 (6): e13377. DOI: 10.1111/acel.13377.
[13] [13] ZHANG X L, LI Y N, YANG P Z, et al. Trimethylamine-N-oxide promotes vascular calcification through activation of NLRP3 (nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3) inflammasome and NF-B (nuclear factor B) signals[J]. Arterioscler Thromb Vasc Biol, 2020, 40(3): 751-765. DOI: 10.1161/ATVBAHA.119.313414.
[14] [14] ROWE P S, MCCARTHY E M, YU A L, et al. Correction of vascular calcification and hyperphosphatemia in CKD rats treated with ASARM peptide[J]. Kidney360, 2022, 3(10): 1683-1698. DOI: 10.34067/KID.0002782022.
[15] [15] MA W Q, SUN X J, ZHU Y, et al. PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming[J]. Cell Death Dis, 2020, 11(11): 991. DOI: 10.1038/s41419-020-03162-w.
[16] [16] SATO H, GOTO M, NISHIMURA G, et al. Upacicalcet, a positive allosteric modulator of the calcium-sensing receptor, prevents vascular calcification and bone disorder in a rat adenine-induced secondary hyperparathyroidism model[J]. Bone, 2023, 167: 116613. DOI: 10.1016/j.bone.2022.116613.
[17] [17] LI Z H, WU J, ZHANG X L, et al. CDC42 promotes vascular calcification in chronic kidney disease[J]. J Pathol, 2019, 249 (4): 461-471. DOI: 10.1002/path.5334.
[18] [18] CHANG J R, GUO J, WANG Y, et al. Intermedin1-53 attenuates vascular calcification in rats with chronic kidney disease by upregulation of -Klotho[J]. Kidney Int, 2016, 89(3): 586-600. DOI: 10.1016/j.kint.2015.12.029.
[19] [19] LEE S J, LEE I K, JEON J H. Vascular calcification-new insights into its mechanism[J]. Int J Mol Sci, 2020, 21(8): 2685. DOI: 10.3390/ijms21082685.
[22] [22] HERRMANN J, BABIC M, TLLE M, et al. Research models for studying vascular calcification[J]. Int J Mol Sci, 2020, 21(6): 2204. DOI: 10.3390/ijms21062204.
[23] [23] BAO Y W, YUAN Y, CHEN J H, et al. Kidney disease models: tools to identify mechanisms and potential therapeutic targets[J]. Zool Res, 2018, 39(2): 72-86. DOI: 10.24272/j.issn.2095-8137.2017.055.
[24] [24] FU Y, TANG C Y, CAI J, et al. Rodent models of AKI-CKD transition[J]. Am J Physiol Renal Physiol, 2018, 315(4): F1098-F1106. DOI: 10.1152/ajprenal.00199.2018.
[25] [25] HERRMANN J, GUMMI M R, XIA M D, et al. Vascular calcification in rodent models-keeping track with an extented method assortment[J]. Biology, 2021, 10(6): 459. DOI: 10.3390/biology10060459.
Get Citation
Copy Citation Text
PAN Yicong, JIANG Wenhong, HU Ming, QIN Xiao. Optimization of Surgical Procedure and Efficacy Evaluation of Aortic Calcification Model in Rats with Chronic Kidney Disease[J]. Laboratory Animal and Comparative Medicine, 2025, 45(3): 279
Category:
Received: Aug. 28, 2024
Accepted: Aug. 26, 2025
Published Online: Aug. 26, 2025
The Author Email: JIANG Wenhong (jwhongxszy@163.com)