Advanced Photonics, Volume. 7, Issue 5, 050501(2025)

Amplifying molecular voices: metasurface-enhanced infrared photothermal microscopy and tomography for ultrasensitive chemical analysis

Chao Zuo1,2,3、* and Qian Chen2,3
Author Affiliations
  • 1Nanjing University of Science and Technology, School of Electronic and Optical Engineering, Smart Computational Imaging Laboratory (SCILab), Nanjing, China
  • 2Jiangsu Key Laboratory of Visual Sensing & Intelligent Perception, Nanjing, China
  • 3State Key Laboratory of Extreme Environment Optoelectronic Dynamic Measurement Technology and Instrument, Taiyuan, China
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    Figures & Tables(1)
    Metasurface-enhanced infrared photothermal microscopy integrated with intensity diffraction tomography. (a) Conceptual 3D schematic of the MEIP system incorporating multi-angle visible laser probe illumination and IDT for volumetric reconstruction of photothermal signals. (b) Zoomed view of the sample region, highlighting the interaction of the IR pump and visible probe beams with the nanoantenna metasurface, along with the corresponding layered tomographic reconstruction of photothermal absorption-induced refractive index changes.
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    Chao Zuo, Qian Chen, "Amplifying molecular voices: metasurface-enhanced infrared photothermal microscopy and tomography for ultrasensitive chemical analysis," Adv. Photon. 7, 050501 (2025)

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    Paper Information

    Category: News and Commentaries

    Received: Jul. 26, 2025

    Accepted: Aug. 4, 2025

    Posted: Aug. 4, 2025

    Published Online: Sep. 2, 2025

    The Author Email: Chao Zuo (zuochao@njust.edu.cn)

    DOI:10.1117/1.AP.7.5.050501

    CSTR:32187.14.1.AP.7.5.050501

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