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Acta Optica Sinica (Online), Volume. 2, Issue 15, 1514003(2025)

Near-Infrared Spectroscopy for Monitoring Ionic Liquids in Pharmaceutical Production

Fangfang Chen1, Ben Li1,2, Fei Wang1,2, Zansheng Zheng3, Yibo Zou4, and Yiting Yu1,2、*
Author Affiliations
  • 1Key Laboratory of Scale Manufacturing Technologies for High-Performance MEMS Chips of Zhejiang Province, Key Laboratory of Optical Microsystems and Application Technologies of Ningbo City, Ningbo Institute of Northwestern Polytechnical University, Ningbo 315103, Zhejiang , China
  • 2Key Laboratory of Micro/Nano Systems for Aerospace (Ministry of Education), Key Laboratory of Micro and Nano Electro-Mechanical Systems of Shaanxi Province, School of Mechanical Engineering, Northwestern Polytechnical University, Xi'an 710072, Shaanxi , China
  • 3Ningbo Chemgoo Pharma Tech Co., Ltd., Ningbo 315103, Zhejiang , China
  • 4Ningbo Smartflow Co., Ltd., Ningbo 315103, Zhejiang , China
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    [1] Huo X S, Chen P, Dai J W et al. Progress and prospect of application of miniatured near infrared spectrometers[J]. Journal of Instrumental Analysis, 41, 1301-1313(2022).

    [2] Beć K B, Grabska J, Huck C W. Principles and applications of miniaturized near-infrared (NIR) spectrometers[J]. Chemistry, 27, 1514-1532(2021).

    [3] Du Z J, Tian W F, Tilley M et al. Quantitative assessment of wheat quality using near-infrared spectroscopy: a comprehensive review[J]. Comprehensive Reviews in Food Science and Food Safety, 21, 2956-3009(2022).

    [4] Beć K B, Grabska J, Huck C W. Near-infrared spectroscopy in bio-applications[J]. Molecules, 25, 2948(2020).

    [5] Liu W Y, Yan Z X, Hao L Z et al. Research progress in the application of spectroscopic technology in the traceability of food origin[J]. Science and Technology of Food Industry, 44, 421-430(2023).

    [6] Chen P, Yang J, Chu X L et al. Research and application progress of near infrared spectroscopy analytical technology in China in the past five years[J]. Chinese Journal of Analytical Chemistry, 52, 1213-1224(2024).

    [7] Kaur G, Kumar H, Singla M. Diverse applications of ionic liquids: a comprehensive review[J]. Journal of Molecular Liquids, 351, 118556(2022).

    [8] Cao J P, Mou Y X, Chen Y Y et al. Applications of ionic liquids in drug research[J]. Acta Pharmaceutica Sinica, 54, 245-257(2019).

    [9] Pei Y C, Zhang Y X, Ma J et al. Ionic liquids for advanced materials[J]. Materials Today Nano, 17, 100159(2022).

    [10] Curreri A M, Mitragotri S, Tanner E E L. Recent advances in ionic liquids in biomedicine[J]. Advanced Science, 8, e2004819(2021).

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    [12] Yun Y H, Li H D, Deng B C et al. An overview of variable selection methods in multivariate analysis of near-infrared spectra[J]. Trends in Analytical Chemistry, 113, 102-115(2019).

    [13] Zhang D Y, Xu Y F, Huang W Q et al. Nondestructive measurement of soluble solids content in apple using near infrared hyperspectral imaging coupled with wavelength selection algorithm[J]. Infrared Physics and Technology, 98, 297-304(2019).

    [14] Zhang J, Hu Y, Zhou L X et al. Progress of chemometric algorithms in near-infrared spectroscopic analysis[J]. Journal of Instrumental Analysis, 39, 1196-1203(2020).

    [15] Araújo M C U, Saldanha T C B, Galvão R K H et al. The successive projections algorithm for variable selection in spectroscopic multicomponent analysis[J]. Chemometrics and Intelligent Laboratory Systems, 57, 65-73(2001).

    [16] Li H D, Liang Y Z, Xu Q S et al. Key wavelengths screening using competitive adaptive reweighted sampling method for multivariate calibration[J]. Analytica Chimica Acta, 648, 77-84(2009).

    [17] Leardi R, González A L. Genetic algorithms applied to feature selection in PLS regression: how and when to use them[J]. Chemometrics and Intelligent Laboratory Systems, 41, 195-207(1998).

    [18] Wold S, Martens H, Wold H. The multivariate calibration problem in chemistry solved by the PLS method[M]. Matrix pencils, 973, 286-293(1983).

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    Fangfang Chen, Ben Li, Fei Wang, Zansheng Zheng, Yibo Zou, Yiting Yu. Near-Infrared Spectroscopy for Monitoring Ionic Liquids in Pharmaceutical Production[J]. Acta Optica Sinica (Online), 2025, 2(15): 1514003

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    Paper Information

    Category: Applied Optics and Optical Instruments

    Received: Jun. 24, 2025

    Accepted: Jul. 9, 2025

    Published Online: Aug. 7, 2025

    The Author Email: Yiting Yu (yyt@nwpu.edu.cn)

    DOI:10.3788/AOSOL250484

    CSTR:32394.14.AOSOL250484

    Topics

    laser devices and laser physics
    Lasers and Laser Optics
    Laser physics
    laser manufacturing
    Instrumentation, Measurement and Metrology