[1] ARNOLD M, ABNET C C, NEALE R E et al. Global burden of 5 major types of gastrointestinal cancer[J]. Gastroenterology, 159, 335-349(2020).

[2] QUMSEYA B, SULTAN S, BAIN P et al. ASGE guideline on screening and surveillance of Barrett's esophagus[J]. Gastrointest Endosc, 90, 335-359.(2019).

[3] ZHANG Q, WANG F, CHEN Z Y et al. Comparison of the diagnostic efficacy of white light endoscopy and magnifying endoscopy with narrow band imaging for early gastric cancer: a meta-analysis[J]. Gastric Cancer, 19, 543-552(2016).

[4] SUBRAMANIAN V, RAGUNATH K. Advanced endoscopic imaging: a review of commercially available technologies[J]. Clin Gastroenterol Hepatol, 12, 368-376.(2014).

[5] HORIUCHI Y, FUJISAKI J, YAMAMOTO N et al. Diagnostic accuracy of demarcation using magnifying endoscopy with narrow-band imaging for Helicobacter pylori-uninfected undifferentiated-type early gastric cancer[J]. Gastric Cancer, 21, 988-997(2018).

[6] CHAO G, YE F, LI T et al. Estimation of invasion depth of early colorectal cancer using EUS and NBI-ME: a meta-analysis[J]. Tech Coloproctol, 23, 821-830(2019).

[7] FISCHER E G. Nuclear morphology and the biology of cancer cells[J]. Acta Cytol, 64, 511-519(2020).

[8] SINGH I, LELE T P. Nuclear morphological abnormalities in cancer: a search for unifying mechanisms[J]. Results Probl Cell Differ, 70, 443-467(2022).

[9] BACKMAN V, WALLACE M B, PERELMAN L T et al. Detection of preinvasive cancer cells[J]. Nature, 406, 35-36(2000).

[10] WALLACE M B, PERELMAN L T, BACKMAN V et al. Endoscopic detection of dysplasia in patients with Barrett's esophagus using light-scattering spectroscopy[J]. Gastroenterology, 119, 677-682(2000).

[11] ROBLES F E, WAX A. Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry[J]. Opt Lett, 35, 360-362(2010).

[12] KNIGHTON N J, COTTLE B K, KELSON B E B et al. Towards intraoperative quantification of atrial fibrosis using light-scattering spectroscopy and convolutional neural networks[J]. Sensors (Basel), 21, 6033(2021).

[13] COSSENTINO M J, WONG R K. Barrett's esophagus and risk of esophageal adenocarcinoma[J]. Semin Gastrointest Dis, 14, 128-135(2003).

[14] BENARON D A, CHEONG W-F, STEVENSON D K. Tissue optics[J]. Science, 276, 2002-2003(1997).

[15] WALLACE V P, CRAWFORD D C, MORTIMER P S et al. Spectrophotometric assessment of pigmented skin lesions: methods and feature selection for evaluation of diagnostic performance[J]. Phys Med Biol, 45, 735-751(2000).

[16] ZONIOS G, PERELMAN L T, BACKMAN V et al. Diffuse reflectance spectroscopy of human adenomatous colon polyps in vivo[J]. Applied Optics, 38, 6628-6637(1999).

[17] DAWSON J, BARKER D, ELLIS D et al. A theoretical and experimental study of light absorption and scattering by in vivo skin[J]. Physics in Medicine & Biology, 25, 695-709(1980).

[18] MARCHESINI R, CASCINELLI N, BRAMBILLA M et al. In vivo spectrophotometric evaluation of neoplastic and non‐neoplastic skin pigmented lesions. II: Discriminant analysis between nevus and melanoma[J]. Photochemistry and Photobiology, 55, 515-522(1992).

[19] MOURANT J R, BIGIO I J, BOYER J et al. Spectroscopic diagnosis of bladder cancer with elastic light scattering[J]. Lasers in Surgery and Medicine, 17, 350-357(1995).

[20] [20] MOURANT J R, BOYER J D, JOHNSON T M, et al. Detection of gastrointestinal cancer by elastic scattering absption spectroscopies with the Los Alamos Optical Biopsy System[C]Advances in Laser Light Spectroscopy to Diagnose Cancer Other Diseases II, 1995: 210217.

[21] PERELMAN L, BACKMAN V, WALLACE M et al. Observation of periodic fine structure in reflectance from biological tissue: a new technique for measuring nuclear size distribution[J]. Physical Review Letters, 80, 627-630(1998).

[22] BEUTHAN J, MINET O, HELFMANN J et al. The spatial variation of the refractive index in biological cells[J]. Physics in Medicine and Biology, 41, 369-382(1996).

[23] PATON J. The scattering of light by small particles[J]. Nature, 182, 1470-1471(1958).

[24] [24] MINCU N, BARTLETT M, JIANG H. Particle sizing in twolayer turbid media using polarized light[C]SPIE, 2001, 4261: 424527.

[25] BRO R, DE Jong S. A fast non‐negativity‐constrained least squares algorithm[J]. Journal of Chemometrics: A Journal of the Chemometrics Society, 11, 393-401(1997).

[26] HUI F, OLLERO M, VITKIN E et al. Noninvasive sizing of subcellular organelles with light scattering spectroscopy[J]. IEEE Journal of Selected Topics in Quantum Electronics, 9, 267-276(2003).

[27] ZHU X, SHEN J, LIU W et al. Nonnegative least-squares truncated singular value decomposition to particle size distribution inversion from dynamic light scattering data[J]. Applied Optics, 49, 6591-6596(2010).

[28] NEUBAUER A. Tikhonov regularisation for non-linear ill-posed problems: optimal convergence rates and finite-dimensional approximation[J]. Inverse Problems, 5, 541(1989).

[29] SIVANANDAM S, DEEPA S, SIVANANDAM S et al. Genetic algorithm optimization problems[J]. Introduction to Genetic Algorithms, 165-209(2008).

[30] WANG D, TAN D, LIU L. Particle swarm optimization algorithm: an overview[J]. Soft Computing, 22, 387-408(2018).

[31] ZHANG W, SHEN J, THOMAS J C et al. Particle size distribution recovery in dynamic light scattering by optimized multi-parameter regularization based on the singular value distribution[J]. Powder Technology, 353, 320-329(2019).

[32] SHAN L, XU L, CAO L et al. Inversion of particle size distribution based on iterative non-negative Philips-Twomey algorithm[J]. Transactions of the Institute of Measurement and Control, 42, 805-812(2020).

[33] ZHANG G, WANG Z, WANG Y et al. Particle size inversion constrained by L∞ Norm for dynamic light scattering[J]. Materials, 15, 7111(2022).

[34] GUO X, CHEN M, PENG L et al. Particle size distribution inversion in dynamic light scattering by adaptive step-size non-negative least squares[J]. Optics Communications, 503, 127444(2022).

[35] MOHAMMAD-DJAFARI A. Regularization, bayesian inference, and machine learning methods for inverse problems[J]. Entropy, 23, 1673(2021).

[36] TUNIYAZI A, MU T, LI Q et al. Bayesian neural networks enabled snapshot polarized light scattering spectroscopy with uncertainty quantification[J]. Optics and Lasers in Engineering, 160, 107298(2023).

[37] ROBLES F E, WILSON C, GRANT G et al. Molecular imaging true-colour spectroscopic optical coherence tomography[J]. Nature Photonics, 5, 744-747(2011).

[38] CANG H, SUN T, LI Z Y et al. Gold nanocages as contrast agents for spectroscopic optical coherence tomography[J]. Opt Lett, 30, 3048-3050(2005).

[39] YI J, GONG J, LI X. Analyzing absorption and scattering spectra of micro-scale structures with spectroscopic optical coherence tomography[J]. Opt Express, 17, 13157-13167(2009).

[40] OLDENBURG A L, HANSEN M N, RALSTON T S et al. Imaging gold nanorods in excised human breast carcinoma by spectroscopic optical coherence tomography[J]. J Mater Chem, 19, 6407-6411(2009).

[41] FABER D J, MIK E G, AALDERS M C et al. Toward assessment of blood oxygen saturation by spectroscopic optical coherence tomography[J]. Opt Lett, 30, 1015-1017(2005).

[42] FABER D J, VAN Leeuwen T G. Are quantitative attenuation measurements of blood by optical coherence tomography feasible?[J]. Opt Lett, 34, 1435-1437(2009).

[43] YI J, LI X. Estimation of oxygen saturation from erythrocytes by high-resolution spectroscopic optical coherence tomography[J]. Opt Lett, 35, 2094-2096(2010).

[44] YI J, BACKMAN V. Imaging a full set of optical scattering properties of biological tissue by inverse spectroscopic optical coherence tomography[J]. Opt Lett, 37, 4443-4445(2012).

[45] YI J, RADOSEVICH A J, STYPULA-CYRUS Y et al. Spatially resolved optical and ultrastructural properties of colorectal and pancreatic field carcinogenesis observed by inverse spectroscopic optical coherence tomography[J]. J Biomed Opt, 19, 36013(2014).

[46] ZHAO Y, MAHER J R, KIM J et al. Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography[J]. Biomed Opt Express, 6, 3339-3345(2015).

[47] KASSINOPOULOS M, BOUSI E, ZOUVANI I et al. Correlation of the derivative as a robust estimator of scatterer size in optical coherence tomography (OCT)[J]. Biomed Opt Express, 8, 1598-1606(2017).

[48] KENDALL W Y, BORDAS J, MIRMINACHI S et al. Spectroscopic optical coherence tomography for classification of colorectal cancer in a mouse model[J]. J Biophotonics, 15, e202100387(2022).

[49] KENDALL W Y, TIAN Q, ZHAO S et al. Deep learning classification of ex vivo human colon tissues using spectroscopic optical coherence tomography[J]. J Biophotonics, e202400082(2024).

[50] WAX A, YANG C, MÜLLER M G et al. In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry[J]. Cancer Res, 63, 3556-3559(2003).

[51] HO D, DRAKE T K, BENTLEY R C et al. Evaluation of hybrid algorithm for analysis of scattered light using ex vivo nuclear morphology measurements of cervical epithelium[J]. Biomed Opt Express, 6, 2755-2765(2015).

[52] WAX A, YANG C, BACKMAN V et al. Cellular organization and substructure measured using angle-resolved low-coherence interferometry[J]. Biophys J, 82, 2256-2264(2002).

[53] CHALUT K J, OSTRANDER J H, GIACOMELLI M G et al. Light scattering measurements of subcellular structure provide noninvasive early detection of chemotherapy-induced apoptosis[J]. Cancer Res, 69, 1199-1204(2009).

[54] TERRY N G, ZHU Y, RINEHART M T et al. Detection of dysplasia in Barrett's esophagus with in vivo depth-resolved nuclear morphology measurements[J]. Gastroenterology, 140, 42-50(2011).

[55] TERRY N, ZHU Y, THACKER J K et al. Detection of intestinal dysplasia using angle-resolved low coherence interferometry[J]. J Biomed Opt, 16, 106002(2011).

[56] HO D, DRAKE T K, SMITH-MCCUNE K K et al. Feasibility of clinical detection of cervical dysplasia using angle-resolved low coherence interferometry measurements of depth-resolved nuclear morphology[J]. Int J Cancer, 140, 1447-1456(2017).

[57] KENDALL W Y, HO D, CHU K et al. Prospective detection of cervical dysplasia with scanning angle-resolved low coherence interferometry[J]. Biomed Opt Express, 11, 5197-5211(2020).

[58] JELLY E T, STEELMAN Z A, ZHANG H et al. Next-generation endoscopic probe for detection of esophageal dysplasia using combined OCT and angle-resolved low-coherence interferometry[J]. Biomed Opt Express, 15, 1943-1958(2024).

[59] YU C C, LAU C, TUNNELL J W et al. Assessing epithelial cell nuclear morphology by using azimuthal light scattering spectroscopy[J]. Opt Lett, 31, 3119-3121(2006).

[60] BACKMAN V, GURJAR R, BADIZADEGAN K et al. Polarized light scattering spectroscopy for quantitative measurement of epithelial cellular structures in situ[J]. IEEE Journal of Selected Topics in Quantum Electronics, 5, 1019-1026(1999).

[61] SHEIL C J, KHAN U, ZAKHAROV Y N et al. Two-photon polymerization nanofabrication of ultracompact light scattering spectroscopic probe for detection of pre-cancer in pancreatic cyst[J]. Optics and Lasers in Engineering, 142, 106616(2021).

[62] QIU L, ZHANG L, TURZHITSKY V et al. Multispectral endoscopy with light gating for early cancer detection[J]. IEEE J Sel Top Quantum Electron, 25, 7201309(2019).

[63] PLESKOW D K, SAWHNEY M S, UPPUTURI P K et al. In vivo detection of bile duct pre-cancer with endoscopic light scattering spectroscopy[J]. Nature Communications, 14, 109(2023).

[64] ZHANG L, PLESKOW D K, TURZHITSKY V et al. Light scattering spectroscopy identifies the malignant potential of pancreatic cysts during endoscopy[J]. Nature Biomedical Engineering, 1, 0040(2017).

[65] SUGIMOTO N, LEE C H. Characteristics of dust aerosols inferred from lidar depolarization measurements at two wavelengths[J]. Appl Opt, 45, 7468-7474(2006).

[66] WEI Y, LIU F, YANG K et al. Passive underwater polarization imaging detection method in neritic area[J]. Acta Physica Sinica-Chinese Edition, 67, 1(2018).

[67] HAIBO L, ZHANG J, GAI X et al. Development status and prospects of polarization imaging technology (Invited)[J]. Infrared and Laser Engineering, 51, 20210987(2022).

[68] TUNIYAZI A, MU T, JIANG X et al. Snapshot polarized light scattering spectroscopy using spectrally-modulated polarimetry for early gastric cancer detection[J]. J Biophotonics, 14, e202100140(2021).

[69] GURJAR R S, BACKMAN V, PERELMAN L T et al. Imaging human epithelial properties with polarized light-scattering spectroscopy[J]. Nature Medicine, 7, 1245-1248(2001).

[70] KIM Y L, YANG L, WALI R K et al. Simultaneous measurement of angular and spectral properties of light scattering for characterization of tissue microarchitecture and its alteration in early precancer[J]. IEEE Journal of Selected Topics in Quantum Electronics, 9, 243-256(2003).

[71] TURZHITSKY V M, GOMES A J, KIM Y L et al. Measuring mucosal blood supply in vivo with a polarization-gating probe[J]. Appl Opt, 47, 6046-6057(2008).

[72] QIU L, PLESKOW D K, CHUTTANI R et al. Multispectral scanning during endoscopy guides biopsy of dysplasia in Barrett's esophagus[J]. Nature Medicine, 16, 603-606(2010).

[73] POHL H, RöSCH T, VIETH M et al. Miniprobe confocal laser microscopy for the detection of invisible neoplasia in patients with Barrett's oesophagus[J]. Gut, 57, 1648-1653(2008).

[74] QIU L, CHUTTANI R, PLESKOW D K et al. Multispectral light scattering endoscopic imaging of esophageal precancer[J]. Light: Science & Applications, 7, 17174(2018).

[75] TUNIYAZI A, MU T, JIANG X et al. Snapshot polarized light scattering spectrometric fiberscopy for early cancer detection[J]. Laser & Photonics Reviews, 2400486(2024).