Experiment Science and Technology, Volume. 21, Issue 5, 27(2023)

Organic Chemistry Comprehensive Experiment: Synthesis of 1-Benzyl-2-Phenylbenzimidazole

Yanqin XU*, Min LIU, Youcai MA, Yuhao CHEN, Xin LI, Xiaohui ZHANG, and Yan XIONG
Author Affiliations
  • School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, China
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    References(6)

    [12] S TAHLAN, S KUMAR, S KAKKAR. Benzimidazole scaffolds as promising antiproliferative agents: A review. BioMed Central Chemistry, 13, 1-16(2019).

    [13] B YOGITA, S OM. The therapeutic journey of benzimidazoles: A review. Bioorganic & Medicinal Chemistry, 20, 6208-6236(2012).

    [14] B KENAN, Ö İSMAIL. 5-Nitrobenzimidazole containing Pd(II) catalyzed CC cross-coupling reactions: The effect of the N-substituent of the benzimidazole structure on catalyst activity. Journal of Molecular Structure, 1192, 172-177(2019).

    [15] H ZHU, D LIU, Y LI et al. Syntheses, crystal structures, and photocatalytic properties of two zinc(II) coordination polymers based on dicarboxylates and flexible bis(benzimidazole) ligands. Polyhedron, 167, 44-50(2019).

    [16] Q LIU, S YUAN, L HU et al. Cross-dehydrogenative coupling strategy for phosphonation and cyanation of secondary N-alkyl anilines by employing 2, 3-dichloro-5, 6-dicyanobenzoquinone. Tetrahedron, 50, 7209-7217(2018).

    [17] H BUI, T BUU, H NGUYEN et al. Facile sodium metabisulfite mediated synthesis of 1, 2-disubstituted benzimidazoles and cytotoxicity evaluation. Heterocycles, 650-665(2019).

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    Yanqin XU, Min LIU, Youcai MA, Yuhao CHEN, Xin LI, Xiaohui ZHANG, Yan XIONG. Organic Chemistry Comprehensive Experiment: Synthesis of 1-Benzyl-2-Phenylbenzimidazole[J]. Experiment Science and Technology, 2023, 21(5): 27

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    Paper Information

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    Received: Mar. 18, 2022

    Accepted: --

    Published Online: Nov. 28, 2023

    The Author Email: XU Yanqin (xuyanqin666@163.com)

    DOI:10.12179/1672-4550.20220161

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