Fig. 1. Near-field optical fiber probe temperature measuring system. (a) Entire system, the inset is a micrograph of a probe with a 100× objective lens; (b) local sketch

Fig. 2. Temperature characteristics of near-field optical fiber temperature probe. (a) Fluorescence spectra collected by the probe at different temperatures; (b) fitted result of fluorescence peak position and temperature

Fig. 3. Temperature measurement results after the cells containing gold nanoparticles were immobilized. (a) Single cell topographic map, illustrated with corresponding three-dimensional results; (b) temperature difference distribution within the cell sample

Fig. 4. Temperature measurement results of living cells. (a) Optical image of cells; (b) temperature distribution in 20 μm×20 μm area